Specific Changes in the Mammalian Gut Microbiome as a Biomarker for Oxytocin-Induced Behavioral Changes
Abstract
:1. Introduction
2. Materials and Methods
2.1. Animal Housing and Samples Collection
2.1.1. Multidrug Environment: Experimental Setup—Experiment 1
2.1.2. Single Drug Environment: Experimental Setup—Experiment 2
2.2. DNA Extraction and Microbiota Analysis
2.3. Behavioral Data
3. Results
3.1. Oxytocin Has a Strong Impact on the Composition of Rat Fecal Microbiota
3.2. Changes in Relative Abundance of Specific Bacterial Taxa
3.3. Specific Bacteria Are Associated with Changes in Behavior
4. Discussion
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Dangoor, I.; Stanić, D.; Reshef, L.; Pešić, V.; Gophna, U. Specific Changes in the Mammalian Gut Microbiome as a Biomarker for Oxytocin-Induced Behavioral Changes. Microorganisms 2021, 9, 1938. https://doi.org/10.3390/microorganisms9091938
Dangoor I, Stanić D, Reshef L, Pešić V, Gophna U. Specific Changes in the Mammalian Gut Microbiome as a Biomarker for Oxytocin-Induced Behavioral Changes. Microorganisms. 2021; 9(9):1938. https://doi.org/10.3390/microorganisms9091938
Chicago/Turabian StyleDangoor, Itzhak, Dušanka Stanić, Leah Reshef, Vesna Pešić, and Uri Gophna. 2021. "Specific Changes in the Mammalian Gut Microbiome as a Biomarker for Oxytocin-Induced Behavioral Changes" Microorganisms 9, no. 9: 1938. https://doi.org/10.3390/microorganisms9091938