In Vitro Reduced Susceptibility to Pentavalent Antimonials of a Leishmania infantum Isolate from a Human Cutaneous Leishmaniasis Case in Central Italy
Abstract
1. Introduction
2. Description of the Case
3. Discussion
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Treatment | L. (L.) infantum Clinical Isolate IC50 (μM) | L. (L.) infantum MHOM/TN/80/IPT1 IC50 (μM) | Unpaired t-Test with Welch’s Correction p-Value |
---|---|---|---|
Potassium antimonyl tartrate trihydrate (SbIII) | 27.06 ± 2.70 | 13.22 ± 2.11 | <0.01 |
Miltefosine | 1.31 ± 0.14 | 4.27 ± 0.40 | <0.01 |
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Diotallevi, A.; Buffi, G.; Corbelli, G.; Ceccarelli, M.; Ortalli, M.; Varani, S.; Magnani, M.; Galluzzi, L. In Vitro Reduced Susceptibility to Pentavalent Antimonials of a Leishmania infantum Isolate from a Human Cutaneous Leishmaniasis Case in Central Italy. Microorganisms 2021, 9, 1147. https://doi.org/10.3390/microorganisms9061147
Diotallevi A, Buffi G, Corbelli G, Ceccarelli M, Ortalli M, Varani S, Magnani M, Galluzzi L. In Vitro Reduced Susceptibility to Pentavalent Antimonials of a Leishmania infantum Isolate from a Human Cutaneous Leishmaniasis Case in Central Italy. Microorganisms. 2021; 9(6):1147. https://doi.org/10.3390/microorganisms9061147
Chicago/Turabian StyleDiotallevi, Aurora, Gloria Buffi, Giovanni Corbelli, Marcello Ceccarelli, Margherita Ortalli, Stefania Varani, Mauro Magnani, and Luca Galluzzi. 2021. "In Vitro Reduced Susceptibility to Pentavalent Antimonials of a Leishmania infantum Isolate from a Human Cutaneous Leishmaniasis Case in Central Italy" Microorganisms 9, no. 6: 1147. https://doi.org/10.3390/microorganisms9061147
APA StyleDiotallevi, A., Buffi, G., Corbelli, G., Ceccarelli, M., Ortalli, M., Varani, S., Magnani, M., & Galluzzi, L. (2021). In Vitro Reduced Susceptibility to Pentavalent Antimonials of a Leishmania infantum Isolate from a Human Cutaneous Leishmaniasis Case in Central Italy. Microorganisms, 9(6), 1147. https://doi.org/10.3390/microorganisms9061147