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Epidemiologic and Epizootic Data of Tularemia in the Past and in the Recent History in Croatia

Faculty of Medicine, University of Rijeka, Brace Branchetta 20, 51 000 Rijeka, Croatia
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Microorganisms 2020, 8(5), 721; https://doi.org/10.3390/microorganisms8050721
Received: 17 April 2020 / Revised: 8 May 2020 / Accepted: 9 May 2020 / Published: 12 May 2020
(This article belongs to the Special Issue Epidemiology of Tularemia and Francisella tularensis)
Tularemia is a zoonotic disease caused by Francisella tularensis. A large number of recent studies have provided an update on the disease characteristics and the distribution across Europe. In Croatia, most of the clinical cases, as well as the reports of the disease in animals, date from the 20th century. In that period, epidemic and epizootic research had given detailed information about endemic regions and their characteristics, including suspected animal hosts and vectors. The region along the middle course of the Sava River, called Middle Posavina, is described as an endemic region, i.e., a “natural focus” of tularemia, in Croatia. In the 21st century, cases of human tularemia are being reported sporadically, with ulceloglandular, oropharyngeal and typhoid forms of disease. A majority of the described cases are linked with the consumption of contaminated food or water. The disease outbreaks still occur in areas along the course of the river Sava and in northwest Croatia. In this review article, we have summarized epidemiologic and epizootic data of tularemia in the past and in recent Croatian history. View Full-Text
Keywords: Francisella; tularemia; Croatia; endemic region Francisella; tularemia; Croatia; endemic region
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Mihelčić, M.; Marečić, V.; Ožanič, M.; Kelava, I.; Knežević, M.; Šantić, M. Epidemiologic and Epizootic Data of Tularemia in the Past and in the Recent History in Croatia. Microorganisms 2020, 8, 721.

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