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Four-Year Environmental Surveillance Program of Legionella spp. in One of Palermo’s Largest Hospitals
Article

Innovative Antibiofilm Smart Surface against Legionella for Water Systems

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Istituto per la Microelettronica e Microsistemi-Consiglio Nazionale delle Ricerche (CNR-IMM), Ottava Strada 5, 95121 Catania, Italy
2
Azienda Ospedaliero Universitaria Policlinico “G. Rodolico-San Marco”, Via S. Sofia 78, 95123 Catania, Italy
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Azienda Sanitaria Provinciale di Catania, Via S. Maria La Grande 5, 95124 Catania, Italy
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Regional Reference Laboratory of Clinical and Environmental Surveillance of Legionellosis, Department of Biomedical and Dental Sciences and Morphofunctional Imaging, Torre Biologica 3p, AOU ‘G. Martino’, University of Messina, Via C. Valeria, S.N.C., 98125 Messina, Italy
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Regional Reference Laboratory of Clinical and Environmental Surveillance of Legionellosis, Department of Medical and Surgical Sciences and Advanced Technologies “G.F. Ingrassia”, University of Catania, Via Sofia 87, 95123 Catania, Italy
*
Author to whom correspondence should be addressed.
Current address: Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale Stagno d’Alcontres 31, 98166 Messina, Italy.
Academic Editors: Teresa Fasciana, Anna Giammanco and Mario Palermo
Microorganisms 2022, 10(5), 870; https://doi.org/10.3390/microorganisms10050870
Received: 2 March 2022 / Revised: 11 April 2022 / Accepted: 19 April 2022 / Published: 21 April 2022
(This article belongs to the Special Issue Legionella pneumophila: A Microorganism with a Thousand Faces)
Legionella pneumophila contamination of water systems is a crucial issue for public health. The pathogen is able to persist in water as free-living planktonic bacteria or to grow within biofilms that adhere to and clog filters and pipes in a water system, reducing its lifespan and, in the case of hospital buildings, increasing the risk of nosocomial infections. The implementation of water management is considered to be the main prevention measure and can be achieved from the optimization of water system architecture, notably introducing new materials and strategies to contrast Legionella biofilm proliferation and so prolong the water system functionality. In this research, we propose a new smart surface against L. pneumophila biofilm formation. This is based on an innovative type of coating consisting of a sulfonated pentablock copolymer (s-PBC, commercially named Nexar™) deposited on top of a polypropylene (PP) coupon in a sandwich filter model. The covering of PP with s-PBC results in a more hydrophilic, acid, and negatively charged surface that induces microbial physiological inhibition thereby preventing adhesion and/or proliferation attempts of L. pneumophila prior to the biofilm formation. The antibiofilm property has been investigated by a Zone of Inhibition test and an in vitro biofilm formation analysis. Filtration tests have been performed as representative of possible applications for s-PBC coating. Results are reported and discussed. View Full-Text
Keywords: Legionella pneumophila; water safety plan; biofilm; smart coatings; s-PBC Legionella pneumophila; water safety plan; biofilm; smart coatings; s-PBC
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MDPI and ACS Style

Filice, S.; Sciuto, E.L.; Scalese, S.; Faro, G.; Libertino, S.; Corso, D.; Timpanaro, R.M.; Laganà, P.; Coniglio, M.A. Innovative Antibiofilm Smart Surface against Legionella for Water Systems. Microorganisms 2022, 10, 870. https://doi.org/10.3390/microorganisms10050870

AMA Style

Filice S, Sciuto EL, Scalese S, Faro G, Libertino S, Corso D, Timpanaro RM, Laganà P, Coniglio MA. Innovative Antibiofilm Smart Surface against Legionella for Water Systems. Microorganisms. 2022; 10(5):870. https://doi.org/10.3390/microorganisms10050870

Chicago/Turabian Style

Filice, Simona, Emanuele L. Sciuto, Silvia Scalese, Giuseppina Faro, Sebania Libertino, Domenico Corso, Rosario M. Timpanaro, Pasqualina Laganà, and Maria A. Coniglio. 2022. "Innovative Antibiofilm Smart Surface against Legionella for Water Systems" Microorganisms 10, no. 5: 870. https://doi.org/10.3390/microorganisms10050870

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