A New Variant of Avian Encephalomyelitis Virus Associated with Neurologic Signs in Turkey Poults
Abstract
:1. Introduction
2. Materials and Methods
2.1. Clinical Cases
2.2. Histopathology
2.3. Sample Processing and RNA Extraction
2.4. Metagenomic Sequencing
2.5. Whole Genome Sequence Analysis
3. Results
3.1. Macroscopic and Microscopic Lesions
3.2. Whole Genome Sequence Analysis
4. Discussion
5. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Genes | Between Novels AEVs Nucleotide (Amino Acid) | With Previous AEVs Nucleotide (Amino Acid) |
---|---|---|
Full-length polyprotein | 99.9% (100%) | 77.7–78.5% (90.3–92.5%) |
P1 region | 99.9–100% (100%) | 78.3–79.7% (93.3–95.2%) |
- VP1 | 99.8–100% (100%) | 77.2–79.7% (92.5–93.3%) |
- VP2 | 100% (100%) | 79.4–81.0% (95.5–97.7%) |
- VP3 | 99.8–100% (100%) | 77.1–79.4% (91.4–95.9%) |
P2-P3 regions | 99.9–100% (100%) | 77.0–78.0% (88.6–91.0%) |
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Temeeyasen, G.; Sharafeldin, T.; Gharaibeh, S.; Sobhy, N.M.; Porter, R.E.; Mor, S.K. A New Variant of Avian Encephalomyelitis Virus Associated with Neurologic Signs in Turkey Poults. Pathogens 2024, 13, 758. https://doi.org/10.3390/pathogens13090758
Temeeyasen G, Sharafeldin T, Gharaibeh S, Sobhy NM, Porter RE, Mor SK. A New Variant of Avian Encephalomyelitis Virus Associated with Neurologic Signs in Turkey Poults. Pathogens. 2024; 13(9):758. https://doi.org/10.3390/pathogens13090758
Chicago/Turabian StyleTemeeyasen, Gun, Tamer Sharafeldin, Saad Gharaibeh, Nader M. Sobhy, Robert E. Porter, and Sunil K. Mor. 2024. "A New Variant of Avian Encephalomyelitis Virus Associated with Neurologic Signs in Turkey Poults" Pathogens 13, no. 9: 758. https://doi.org/10.3390/pathogens13090758
APA StyleTemeeyasen, G., Sharafeldin, T., Gharaibeh, S., Sobhy, N. M., Porter, R. E., & Mor, S. K. (2024). A New Variant of Avian Encephalomyelitis Virus Associated with Neurologic Signs in Turkey Poults. Pathogens, 13(9), 758. https://doi.org/10.3390/pathogens13090758