Next Article in Journal
Psychological Adaptations to High-Intensity Interval Training in Overweight and Obese Adults: A Topical Review
Previous Article in Journal
Olympic Cycle Comparison of the Nutritional and Cardiovascular Health Status of an Elite-Level Female Swimmer: Case Study Report from Slovenia
 
 
Article

Exploring the Effects of Six Weeks of Resistance Training on the Fecal Microbiome of Older Adult Males: Secondary Analysis of a Peanut Protein Supplemented Randomized Controlled Trial

1
School of Kinesiology, Auburn University, Auburn, AL 36849, USA
2
Department of Nutrition, Dietetics and Hospitality Management, College of Human Sciences, Auburn University, Auburn, AL 36849, USA
3
Department of Cell, Developmental, and Integrative Biology, Division of Preventive Medicine, University of Alabama at Birmingham, Birmingham, AL 35294, USA
4
Department of Cell Biology and Physiology, Edward Via College of Osteopathic Medicine-Auburn Campus, Auburn, AL 36832, USA
*
Author to whom correspondence should be addressed.
Academic Editor: Richard B. Kreider
Sports 2022, 10(5), 65; https://doi.org/10.3390/sports10050065
Received: 2 March 2022 / Revised: 14 April 2022 / Accepted: 18 April 2022 / Published: 22 April 2022
The bacteria inhabiting the gastrointestinal tract contribute to numerous host functions and can be altered by lifestyle factors. We aimed to determine whether a 6-week training intervention altered fecal microbiome diversity and/or function in older males. Fecal samples were collected prior to and following a 6-week twice-weekly supervised resistance training intervention in 14 older Caucasian males (65 ± 10 years, 28.5 ± 3.2 kg/m2) with minimal prior training experience. Participants were randomized to receive a daily defatted peanut powder supplement providing 30 g protein (n = 8) or no supplement (n = 6) during the intervention. Bacterial DNA was isolated from pre-and post-training fecal samples, and taxa were identified using sequencing to amplify the variable region 4 (V4) of the 16S ribosomal RNA gene. Training significantly increased whole-body and lower-body lean mass (determined by dual energy X-ray absorptiometry) as well as leg extensor strength (p < 0.05) with no differences between intervention groups. Overall composition of the microbiome and a priori selected taxa were not significantly altered with training. However, MetaCYC pathway analysis indicated that metabolic capacity of the microbiome to produce mucin increased (p = 0.047); the tight junction protein, zonulin, was measured in serum and non-significantly decreased after training (p = 0.062). Our data suggest that resistance training may improve intestinal barrier integrity in older Caucasian males; further investigation is warranted. View Full-Text
Keywords: resistance training; gut microbiome; aging; intestinal barrier integrity resistance training; gut microbiome; aging; intestinal barrier integrity
Show Figures

Figure 1

MDPI and ACS Style

Moore, J.H.; Smith, K.S.; Chen, D.; Lamb, D.A.; Smith, M.A.; Osburn, S.C.; Ruple, B.A.; Morrow, C.D.; Huggins, K.W.; McDonald, J.R.; Brown, M.D.; Young, K.C.; Roberts, M.D.; Frugé, A.D. Exploring the Effects of Six Weeks of Resistance Training on the Fecal Microbiome of Older Adult Males: Secondary Analysis of a Peanut Protein Supplemented Randomized Controlled Trial. Sports 2022, 10, 65. https://doi.org/10.3390/sports10050065

AMA Style

Moore JH, Smith KS, Chen D, Lamb DA, Smith MA, Osburn SC, Ruple BA, Morrow CD, Huggins KW, McDonald JR, Brown MD, Young KC, Roberts MD, Frugé AD. Exploring the Effects of Six Weeks of Resistance Training on the Fecal Microbiome of Older Adult Males: Secondary Analysis of a Peanut Protein Supplemented Randomized Controlled Trial. Sports. 2022; 10(5):65. https://doi.org/10.3390/sports10050065

Chicago/Turabian Style

Moore, Johnathon H., Kristen S. Smith, Dongquan Chen, Donald A. Lamb, Morgan A. Smith, Shelby C. Osburn, Bradley A. Ruple, Casey D. Morrow, Kevin W. Huggins, James R. McDonald, Michael D. Brown, Kaelin C. Young, Michael D. Roberts, and Andrew D. Frugé. 2022. "Exploring the Effects of Six Weeks of Resistance Training on the Fecal Microbiome of Older Adult Males: Secondary Analysis of a Peanut Protein Supplemented Randomized Controlled Trial" Sports 10, no. 5: 65. https://doi.org/10.3390/sports10050065

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop