Next Article in Journal
The Rise and Demise of Integrated Pest Management in Rice in Indonesia
Next Article in Special Issue
Parasitic Manipulation of Host Behaviour: Baculovirus SeMNPV EGT Facilitates Tree-Top Disease in Spodoptera exigua Larvae by Extending the Time to Death
Previous Article in Journal
Insect Pathogenic Bacteria in Integrated Pest Management
Article Menu

Export Article

Open AccessArticle
Insects 2015, 6(2), 368-380;

Tissue-Specific Immune Gene Expression in the Migratory Locust, Locusta Migratoria

School of Biological Sciences, The University of Sydney, NSW 2006, Australia
Plant Functional Biology and Climate Change Cluster, University of Technology Sydney, New South Wales 2007, Australia
The Charles Perkins Centre, The University of Sydney, NSW 2006, Australia
Author to whom correspondence should be addressed.
Academic Editors: Kenneth Wilson and Sheena Cotter
Received: 3 March 2015 / Revised: 2 April 2015 / Accepted: 8 April 2015 / Published: 16 April 2015
(This article belongs to the Special Issue Parasite-Insect Interactions)
Full-Text   |   PDF [230 KB, uploaded 16 April 2015]   |  


The ability of hosts to respond to infection involves several complex immune recognition pathways. Broadly conserved pathogen-associated molecular patterns (PAMPs) allow individuals to target a range of invading microbes. Recently, studies on insect innate immunity have found evidence that a single pathogen can activate different immune pathways across species. In this study, expression changes in immune genes encoding peptidoglycan-recognition protein SA (PGRP-SA), gram-negative binding protein 1 (GNBP1) and prophenoloxidase (ProPO) were investigated in Locusta migratoria, following an immune challenge using injected lipopolysaccharide (LPS) solution from Escherichia coli. Since immune activation might also be tissue-specific, gene expression levels were followed across a range of tissue types. For PGRP-SA, expression increased in response to LPS within all seven of the tissue-types assayed and differed significantly between tissues. Expression of GNBP1 similarly varied across tissue types, yet showed no clear expression difference between LPS-injected and uninfected locusts. Increases in ProPO expression in response to LPS, however, could only be detected in the gut sections. This study has revealed tissue-specific immune response to add a new level of complexity to insect immune studies. In addition to variation in recognition pathways identified in previous works, tissue-specificity should be carefully considered in similar works. View Full-Text
Keywords: insect immunity; gene expression; tissue-specificity; locust insect immunity; gene expression; tissue-specificity; locust

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

Share & Cite This Article

MDPI and ACS Style

Pulpitel, T.; Pernice, M.; Simpson, S.J.; Ponton, F. Tissue-Specific Immune Gene Expression in the Migratory Locust, Locusta Migratoria. Insects 2015, 6, 368-380.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics



[Return to top]
Insects EISSN 2075-4450 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top