Next Article in Journal
Ozone Effectiveness on Wheat Weevil Suppression: Preliminary Research
Next Article in Special Issue
Reproduction of Distinct Varroa destructor Genotypes on Honey Bee Worker Brood
Previous Article in Journal
Lethal Effects of High Temperatures on Brown Marmorated Stink Bug Adults before and after Overwintering
Previous Article in Special Issue
Effect of Abscisic Acid (ABA) Combined with Two Different Beekeeping Nutritional Strategies to Confront Overwintering: Studies on Honey Bees’ Population Dynamics and Nosemosis
Open AccessReview

Natural Product Medicines for Honey Bees: Perspective and Protocols

1
USDA-ARS Bee Research Laboratory, BLDG. 306, RM. 315, BARC-EAST, Beltsville, MD 20705, USA
2
Department of Chemistry, Fort Lewis College, 1000 Rim Drive, Durango, CO 81301, USA
3
Department of Biological Sciences, Fort Lewis College, 1000 Rim Drive, Durango, CO 81301, USA
4
Honeybee Research Institute, Jiangxi Agricultural University, Zhimin Avenue 1101, Nanchang 330045, China
5
Granite Point Ventures LLC, 10 Lakeview Circle, Greenbelt, MD 20770, USA
*
Authors to whom correspondence should be addressed.
Insects 2019, 10(10), 356; https://doi.org/10.3390/insects10100356
Received: 23 August 2019 / Revised: 7 October 2019 / Accepted: 8 October 2019 / Published: 18 October 2019
(This article belongs to the Special Issue Biology of Social Insect Diseases)
The western honey bee remains the most important pollinator for agricultural crops. Disease and stressors threaten honey bee populations and productivity during winter- and summertime, creating costs for beekeepers and negative impacts on agriculture. To combat diseases and improve overall bee health, researchers are constantly developing honey bee medicines using the tools of microbiology, molecular biology and chemistry. Below, we present a manifesto alongside standardized protocols that outline the development and a systematic approach to test natural products as ‘bee medicines’. These will be accomplished in both artificial rearing conditions and in colonies situated in the field. Output will be scored by gene expression data of host immunity, bee survivorship, reduction in pathogen titers, and more subjective merits of the compound in question. Natural products, some of which are already encountered by bees in the form of plant resins and nectar compounds, provide promising low-cost candidates for safe prophylaxis or treatment of bee diseases. View Full-Text
Keywords: honey bees; bee disease; colony loss; natural product; traditional medicine; screening; virus honey bees; bee disease; colony loss; natural product; traditional medicine; screening; virus
Show Figures

Graphical abstract

MDPI and ACS Style

Tauber, J.P.; Collins, W.R.; Schwarz, R.S.; Chen, Y.; Grubbs, K.; Huang, Q.; Lopez, D.; Peterson, R.; Evans, J.D. Natural Product Medicines for Honey Bees: Perspective and Protocols. Insects 2019, 10, 356.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop