Predicting Loss of Efficacy after Non-Medical Switching: Correlation between Circulating TNF-α Levels and SB4 in Etanercept to SB4 Switchers and Naïve Patients with Rheumatic Disease
Round 1
Reviewer 1 Report
Authors presented their research on the effect of switching of biosimilar from its reference drug and the correlation of drug levels and TNF activity in evaluating responders and non responder patient population.
The study is well written with clear intro, methodology, results and discussion.
Needs minor English correction.
Author Response
We thank the reviewer for the positive feedback. In accordance with the suggestion of the reviewer, we uploaded a new version of the article with English corrections.Author Response File: Author Response.docx
Reviewer 2 Report
I congratulate the authors for considering that the purpose of this study is to be the first to investigate how NMS between Etanercept(ETN)/source and SB4/biosimilar in a multiple RD cohort affects the efficacy of treatment.
Author Response
We thank the reviewer for appreciating our study, we are really glad to have had its positive feedback .