Dermoscopy of Cutaneous Melanoma Metastases: A Comprehensive Literature Review
Abstract
1. Introduction
2. Materials and Methods
3. Results
3.1. Literature Review
3.2. Global Dermoscopic Features and Pigmentation Patterns
3.3. Focal Dermoscopic Features
3.4. Dermoscopic Features of Vascular Structures
4. Discussion
5. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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| Global CMM Features | Focal CMM Features | |||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| N° of Lesions | Homogeneous Main Color Pigmentation | Amelanotic | Vascular | Saccular | Nevus Like Pattern * | Angioma-Like | Black Dots or Globules Irregular Distributed | Light Brown Halo | Peripheral Gray Dots | Crystalline Structures | Peripheral Erythema | Lacune Like Areas | ||||||
| Brown or Gray | Brown or Black | Whitish or Gray | Blue | Pink or Red | Two or More Colors | |||||||||||||
| Pizzichetta et al., [23] | 4 | - | - | - | - | - | 1 | - | - | - | 3 | - | - | - | - | - | - | - |
| Bono et al., [5] | 130 | 51 | 21 | - | 16 | 42 | 5 | 42 | - | - | - | - | - | 53 | 33 | - | 16 | - |
| Virgili et al., [14] | 1 | - | - | 1 | - | - | - | - | - | - | - | - | 1 | - | - | - | - | - |
| Minagawa et al., [15] | 1 | - | - | - | - | - | - | 1 | - | - | - | - | - | - | - | - | - | - |
| Contreras-Steyls et al., [16] | 1 | - | 1 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| Jaimes et al., [17] | 47 | - | - | - | - | - | - | 47 | - | - | - | - | - | - | - | - | - | - |
| Costa et al., [11] | 71 | - | 11 | - | 22 | - | - | - | 14 | - | - | 9 | 15 | - | - | - | - | 8 |
| Duman et al., [18] | 1 | - | - | - | - | - | 1 | - | - | - | - | - | - | - | - | - | - | - |
| Hoelt et al., [19] | 3 | 1 | - | - | 1 | - | 1 | - | - | - | - | - | - | - | - | - | - | - |
| Perrot et al., [20] | 1 | - | - | - | - | - | 1 | - | - | - | - | - | - | - | - | - | - | - |
| Ribero et al., [21] | 1 | - | - | - | 1 | - | - | - | - | - | - | - | - | - | 1 | 1 | - | |
| Pertusi et al., [25] | 8 | 2 | - | - | 2 | - | - | 2 | - | 1 | 5 | - | 2 | 1 | 1 | - | 1 | - |
| Álvarez-Chinchilla et al., [28] | 11 | - | - | - | - | - | 11 | - | - | - | - | - | - | - | - | - | - | - |
| Mazzella et al., [22] | 2 | - | 1 | - | - | - | - | - | - | - | - | - | 1 | - | - | - | - | - |
| Paganelli et al., [24] | 1 | - | 1 | - | - | - | - | - | - | - | - | - | 1 | - | - | - | - | - |
| Avilés-Izquierdo et al., [8] | 150 | - | 37 | - | 34 | 42 | 37 | - | - | - | - | - | 37 | 53 | 51 | 48 | 15 | 13 |
| Kostaki et al., [26] | 42 | - | - | - | - | - | 13 | 12 | - | 7 | - | - | - | - | - | - | - | - |
| Simionescu et al., [9] | 715 | 42 | 66 | 139 | 162 | 71 | - | - | - | - | 137 | - | 46 | - | - | - | - | - |
| Tiodorovic et al., [10] | 158 | - | - | 104 | - | - | - | - | - | - | - | - | - | - | - | - | - | 2 |
| Vessels Dermoscopic Structures | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Linear | Glomerular | Dotted | Serpentine | Milky Red Areas | Hairpin | Corkscrew-Winding | Arborizing | Curved | Two or More Vascular Patterns | |
| Bono et al., [5] | - | - | - | - | - | - | 34 | - | - | 25 |
| Virgili et al., [14] | 1 | - | - | - | - | - | - | - | - | - |
| Minagawa et al., [15] | - | - | - | - | - | - | - | - | - | 1 |
| Jaimes et al., [17] | - | 14 | 7 | 21 | 2 | 11 | 9 | 8 | - | 2 |
| Costa et al., [11] | - | - | - | - | - | - | 5 | 1 | - | 7 |
| Chernoff et al., [27] | - | - | - | - | - | - | - | - | - | 1 |
| Duman et al., [18] | 1 | - | - | - | - | 1 | - | 1 | - | |
| Hoelt et al., [19] | - | - | - | - | 1 | - | 1 | - | - | 1 |
| Pertusi et. al., [25] | 3 | - | 1 | - | - | - | - | 1 | - | 1 |
| Avilés-Izquierdo et al., [8] | 40 | 18 | 15 | 9 | 7 | 6 | 3 | 3 | - | 50 |
| Kostaki et al., [26] | - | - | - | - | - | - | 4 | - | - | 2 |
| Simionescu et al., [9] | 18 | - | 33 | 2 | 1 | 8 | 5 | 2 | 10 | - |
| Tiodorovic et al., [10] | - | - | - | 104 | - | - | - | - | - | - |
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D’Onghia, M.; Agueci, S.; Scotti, B.; Falcinelli, F.; Lo Conte, S.; Cartocci, A.; Cortez, C.D.; Dika, E.; Tognetti, L.; Rubegni, P.; et al. Dermoscopy of Cutaneous Melanoma Metastases: A Comprehensive Literature Review. Diagnostics 2026, 16, 738. https://doi.org/10.3390/diagnostics16050738
D’Onghia M, Agueci S, Scotti B, Falcinelli F, Lo Conte S, Cartocci A, Cortez CD, Dika E, Tognetti L, Rubegni P, et al. Dermoscopy of Cutaneous Melanoma Metastases: A Comprehensive Literature Review. Diagnostics. 2026; 16(5):738. https://doi.org/10.3390/diagnostics16050738
Chicago/Turabian StyleD’Onghia, Martina, Serena Agueci, Biagio Scotti, Francesca Falcinelli, Sofia Lo Conte, Alessandra Cartocci, Christian Dorado Cortez, Emi Dika, Linda Tognetti, Pietro Rubegni, and et al. 2026. "Dermoscopy of Cutaneous Melanoma Metastases: A Comprehensive Literature Review" Diagnostics 16, no. 5: 738. https://doi.org/10.3390/diagnostics16050738
APA StyleD’Onghia, M., Agueci, S., Scotti, B., Falcinelli, F., Lo Conte, S., Cartocci, A., Cortez, C. D., Dika, E., Tognetti, L., Rubegni, P., Perrot, J., & Cinotti, E. (2026). Dermoscopy of Cutaneous Melanoma Metastases: A Comprehensive Literature Review. Diagnostics, 16(5), 738. https://doi.org/10.3390/diagnostics16050738

