Next Article in Journal
Metabolic Syndrome and Hemorrhagic Stroke in Hispanic Elderly Patients with Cerebral Cavernous Malformations
Previous Article in Journal
Equation Built by Multiple Adaptive Regression Spline to Estimate Biological Age in Healthy Postmenopausal Women in Taiwan
 
 
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
Article

Relationships Between Functional Impairment, Depressive Symptoms, and Ageing Attitudes in Older Adults

1
Centre for Healthy Brain Ageing, Discipline of Psychiatry & Mental Health, Faculty of Medicine & Health, University of New South Wales (UNSW), Sydney 2052, Australia
2
School of Psychology and Public Health, La Trobe University, Melbourne 3086, Australia
*
Author to whom correspondence should be addressed.
Diagnostics 2025, 15(9), 1145; https://doi.org/10.3390/diagnostics15091145
Submission received: 26 March 2025 / Revised: 27 April 2025 / Accepted: 28 April 2025 / Published: 30 April 2025

Abstract

:
Background/Objectives: Negative attitudes towards ageing, depressive symptoms, and impairment in instrumental activities of daily living (IADL) are associated with worse health outcomes in older adults, including increased risk of dementia. Little is known about the longitudinal impact of depressive symptoms and functional impairment on ageing attitudes in older people. Identifying the relationships between these risk factors may help inform interventions targeting early dementia. The aim of this study was to determine whether depressive symptoms and functional impairment are associated with ageing attitudes over 6 years. Methods: Participants included 172 community-dwelling adults aged 76–96 years without dementia from the Sydney Memory and Ageing Study who were followed up over 6 years. Multiple linear regression models were used to examine prospective relationships between depressive symptoms, IADL (informant-reported or performance-based) and ageing attitudes. Results: After adjusting for potential confounding variables, more baseline depressive symptoms were associated with more negative ageing attitudes towards physical change (B = −0.10, 95%CI −0.18 to −0.02, p = 0.021) and psychological growth (B = −0.09, 95%CI −0.17 to −0.01, p = 0.037), and worse informant-reported IADL was associated with more negative ageing attitudes towards psychosocial change (B = −0.36, 95%CI −0.64 to −0.09, p = 0.010) over 6 years. Conclusions: The results highlight the importance of assessing and treating depressive symptoms and functional decline in older people, as they are significantly associated with negative attitudes about the ageing process, a known risk factor of worse health outcomes, including dementia.

1. Introduction

The global prevalence of dementia is projected to exceed 152 million by 2050 [1,2], making it the seventh leading cause of death across all age groups and the fourth leading cause for individuals aged 70 or older [3]. Approximately 40% of dementia cases are attributed to modifiable lifestyle factors, such as diet, physical activity, and mental health [4]. Consequently, understanding and mitigating these risk factors has become a global healthcare priority. However, while many studies focus on dementia-related risk factors, less attention has been paid to how psychological and functional factors are associated with attitudes toward ageing (ATA), which themselves are important predictors of health and well-being [5,6]. This is all the more important given the high prevalence of mental health conditions in an ageing population, with depression affecting approximately 35.1% of older adults worldwide [7] and the number of people aged over 60 expected to reach 2.1 billion by 2050 [8].
Attitudes toward ageing (ATAs) refer to an individual’s beliefs, perceptions, and experiences associated with the ageing process. These attitudes are multidimensional, encompassing both positive and negative dimensions [9], and are distinct from other constructs, such as depressive symptoms or overall well-being [10]. Positive ATA has been consistently linked with better physical health [2,5,6], cognitive performance, and longevity, as well as healthier behaviours, such as increased physical activity and adherence to medical advice [1]. Conversely, negative ATA is associated with poorer functional health, cognitive decline, and increased risk of mortality [11]. Importantly, research has shown that ATA not only predicts health outcomes but is also affected by psychological and functional factors over time [12,13,14].
Depressive symptoms are a significant psychological factor that may shape ATA [15,16,17,18,19]. Evidence suggests that depressive symptoms may affect ATA through mechanisms such as reduced self-efficacy, heightened perceptions of physical decline, and lower engagement in positive health behaviours [10]. These pathways highlight the complex interplay between mood and attitudes toward ageing, warranting further investigation. Depression is associated with a 50 per cent higher risk of developing dementia, and its severity has been shown to predict worse health outcomes [15]. Furthermore, there is evidence that depressive symptoms contribute to more negative ATA over time and that positive ATA may mitigate the progression of depressive symptoms [16,17]. However, the longitudinal interplay between depressive symptoms and ATA remains underexplored, particularly in older adults.
Functional impairment, particularly in instrumental activities of daily living (IADLs), is another factor that may affect ATA. IADLs encompass complex, everyday tasks such as managing finances, handling medications, and shopping, which require the integration of multiple cognitive and physical abilities [20]. Impairment in IADL has been identified as a key marker of early cognitive decline and a predictor of dementia risk [21,22,23]. IADLs are commonly assessed using informant-reported measures, such as the Bayer-Activities of Daily Living (B-ADL) scale [24], or performance-based tasks, such as the Sydney Test of Activities of Daily Living in Memory Disorders (STAM) [25]. Recent studies from McGarrigle et al. (2022) and Diehl et al. (2020) suggest that performance-based assessments may offer greater sensitivity in detecting early functional decline, while informant-reported measures can capture a broader context of daily challenges [6,26]. Both approaches underscore the relationship between functional capacity and ATA, providing complementary insights. While research indicates that positive ATA is associated with better future IADL [26,27] and negative ATA with greater IADL impairment [26], little is known about how different measures of IADL—such as informant-reported versus performance-based assessments—might differentially predict ATA over time. Given that performance-based IADL measures are less affected by biases such as mood or carer burden [25], they may offer unique insights into the relationship between functional decline and ATA.
Despite substantial research on ATA as predictors of health outcomes, fewer studies have examined the reverse relationship: how psychological and functional factors, such as depressive symptoms and IADL, are longitudinally associated with ATA. Understanding these relationships is critical, as ATAs are modifiable and have the potential to mediate health outcomes in older adults [1]. Interventions such as cognitive-behavioural therapy to improve ageing attitudes or programs targeting functional independence through physical rehabilitation and support with IADL have shown promise in promoting positive ATA [5,6]. These practical applications highlight the importance of addressing both psychological and functional domains to foster healthier ageing trajectories. Moreover, the distinction between informant-reported and performance-based IADL assessments may provide nuanced insights that are relevant for designing targeted interventions for improving ATA.
Furthermore, despite growing evidence linking depressive symptoms and functional impairment to more negative attitudes towards ageing (ATA), key gaps remain. Most prior research has relied on self-reported functional measures and examined global ATA rather than specific domains (e.g., psychosocial loss, physical change, psychological growth). Additionally, the relative contributions of performance-based versus informant-reported functional measures to the development of ageing attitudes have not been compared. This is particularly important in very old adults (aged 75 and over), a population at increased risk for functional decline, depressive symptoms, and internalised ageism [28,29] but often underrepresented in longitudinal research. The current study addresses these gaps by examining how depressive symptoms and both informant-reported and performance-based instrumental activities of daily living (IADLs) predict three distinct domains of ageing attitudes (physical change, psychosocial loss, and psychological growth) over a six-year period in a large cohort of community-dwelling older adults, aged 75 and above. Few studies have explored these relationships longitudinally or in very old adults—a group particularly vulnerable to both internalised stigma and adverse health outcomes. Drawing on stereotype embodiment theory [30], which posits that internalised ageing stereotypes impact health trajectories, we explored how psychological and functional experiences shape older adults’ perceptions of ageing. By examining these relationships, this research contributes to a growing body of literature on ageing attitudes and their role in promoting healthy ageing [5]. In doing so, the findings from this study can inform the development of interventions targeting depressive symptoms and functional impairments to improve attitudes toward ageing and, ultimately, health outcomes in older populations.

2. Materials and Methods

2.1. Participants

This study employed a longitudinal observational design to examine predictors of ageing attitudes over a six-year period in a sample of 1037 community-dwelling individuals aged 70–90 years without dementia at baseline from the Sydney Memory and Ageing Study (MAS) [31]. Participants were randomly selected through the Electoral Roll in Sydney’s East and were required to be proficient enough in English to complete a psychometric assessment and consent to participate in this study. Participants with psychotic symptoms, schizophrenia or bipolar disorder, developmental disabilities, multiple sclerosis, or other conditions that potentially could have prevented them from completing assessments were excluded. Recruitment and initial assessment occurred between 2005 and 2007 [31]. Participant assessments were conducted every two years (called a ‘wave’) by trained research assistants at either a study centre or participants’ own homes. Assessments at each follow-up involved an interview, questionnaires, a medical examination, and a comprehensive neuropsychological assessment. Informants, who were close friends or family of participants who knew them well enough to report on their functional status and spent at least one hour per week with the participant, completed questionnaires and a phone interview about the participant.
For this study, the baseline was wave 4; as this was the first wave, the performance-based IADL measure was introduced, and participants were followed over 6 years until wave 7. Wave 4 included 708 participants. Participants with a previous or new diagnosis of dementia by wave 4 were excluded (n = 82). Further, participants were only included in the present study if they remained in the study at wave 7 and had complete ATA data. Thus, for the present study, 172 participants with complete wave 7 ATA data were included. Of these, the majority had a study informant at wave 4 (n = 149, 86.6%). Participants’ mean age was 81.2 years (SD = 3.6), 60.5% were women (n = 104), 98.8% were Caucasian (n = 170), and the mean years of education was 12.5 (SD = 3.4). Figure 1 presents a flowchart of the sample selection process for this study.
Participants and informants gave informed consent. This study was approved by the Human Research Ethics Committee of the University of New South Wales (HC: 05037, 09382, 14327, 190962).

2.2. Measures

Attitudes towards ageing (ATA) were measured using the self-rated 12-item Attitudes to Ageing Questionnaire, Short Form (AAQ-SF) [9,32], a psychometrically robust measure of ATA [9]. The AAQ-SF is comprised of 3 subscales with 4 items each. The Psychological Growth subscale assessed attitudes towards perceived gains associated with age; the Physical Change subscale focused on perceived health and vitality in relation to age; the Psychosocial Loss subscale reflected the apparent psychological and social losses experienced as participants age. Participants were asked to rate their feelings according to statements (e.g., “It is a privilege to grow old”, “My health is better than I expected for my age”) on a 5-point scale (1 “Strongly Disagree” to 5 “Strongly Agree”) [9]. The Psychosocial Loss subscale was reverse scored as it had negatively worded statements and thereafter labelled as Psychosocial Change. AAQ-SF subscale scores were averaged across their four items. For AAQ-SF scores, higher scores indicate more positive ATA. Imputation was used to impute missing item scores, and Confirmatory Factor Analysis (CFA) was conducted to examine the factor structure (see Statistical Analysis for details).
Depressive symptoms were assessed using the self-reported, 15-item Geriatric Depression Scale (GDS-15) [33,34], which has been shown to be a valid and reliable indicator of depressive symptoms in older adults [9]. Participants answered “yes” or “no” questions with total scores ranging from 0 to 15, where a higher score indicates more depressive symptoms. In the MAS study, the GDS-15 version with item 9, as described by Brink [35], was used. Scores were pro-rated to account for missing data.
IADL were assessed through two measures: the informant-reported Bayer-Activities of Daily Living (B-ADL) [24] scale and the performance-based Sydney Test of Activities of Daily Living in Memory Disorders (STAM) [25]. The B-ADL [24] is a 25-item questionnaire that has good validity and reliability in measuring IADL impairment [36]. The B-ADL was completed by the participant’s informant. Each question asked how often the participant has difficulties completing a specific activity (e.g., using a telephone, shopping, counting out money, etc.) and was scored on a 10-point scale, with 1 indicating “Never” and 10 indicating “Always”. Scores were pro-rated to account for missing data. Higher scores indicate greater IADL impairment. The Sydney Test of Activities of Daily Living in Memory Disorders (STAM) [25] is a performance-based measure of IADL that consists of 9 tasks covering the functional domains of communication, dressing, handling finances, managing everyday activities, time orientation, medication management, shopping, counting money, and memory. Each of these 9 tasks contains 4 items, resulting in a maximum total score of 36. Higher scores indicate better IADL function. STAM scores were adjusted in 3 ways: items were scored as missing if a physical disability prevented a participant from performing a task, scores were adjusted and penalised if the time taken to complete a task was over the time limit, and the total score was adjusted for the maximum possible score of valid items, which excluded missing items. The STAM has been shown to be a valid and reliable measure of IADL performance in those with normal cognition, MCI, and dementia [25].
Covariates included participants’ age, sex, and years of education, as well as global cognition, cardiovascular risk, vision impairment and arthritis. These covariates were included as they have been shown to impact IADL performance [25,37,38] and may have an effect on ATA. Global cognition was assessed through a comprehensive neuropsychological test battery measuring memory, attention, language, visuospatial ability, and executive function [31]. Global cognition composite scores (interpreted as z-scores) were computed by averaging the domain scores and standardising them against a baseline healthy subsample, with higher scores indicating better cognitive performance [39]. Cardiovascular risk (CVR) scores were calculated according to the Framingham Stroke Study [40], which incorporates diabetic status, total cholesterol level, high-density lipoprotein level, systolic blood pressure, anti-hypertensive treatment, and smoking status. Vision impairment and arthritis status were self-reported at baseline, and participants answered if, in the last two years, they had any visual impairment and if they were diagnosed with arthritis.

2.3. Statistical Analysis

Baseline demographics and other relevant covariates, including global cognition, CVR scores, arthritis, and vision impairment, were compared between the completers and non-completers of the AAQ-SF at wave 7. Demographics and covariates at baseline (wave 4) for the 172 participants included in the current study and the 537 excluded participants were compared to examine whether there were group-level differences at baseline between completers and non-completers. Baseline demographics and covariates were also compared between the AAQ-SF completers who were included and excluded from the multiple linear regressions.
Across the 12-item AAQ-SF, missing data were between 1.2–5.2%. Moreover, among the 26 participants with missing data, the majority (n = 23) had three or fewer items missing. Given that there were relatively few missing data points and that pro-rating across subscales was not appropriate, missing AAQ-SF item scores were imputed. Similar mean and distribution of AAQ-SF scores were obtained using the raw and imputed data.
CFA using the maximum likelihood estimation was conducted to examine the proposed three-factor structure. The model fitted the data adequately after specifying two additional residual covariances: χ2(49) = 100.084, p < 0.001, CFI = 0.914, RMSEA = 0.078, and SRMR = 0.066. All items significantly loaded onto their corresponding factors. Factor correlations ranged from 0.239 to 0.369. These results support the notion that the AAQ-SF subscales need to be examined separately [9].
The relationships between AAQ-SF, GDS-15, B-ADL, and STAM scores at wave 4 and wave 7 were investigated through Spearman’s rank order correlation, given that some of these variables were skewed.
Multiple linear regressions were conducted to assess the prospective relationships between the GDS-15, B-ADL, and STAM at wave 4 and AAQ-SF subscale scores at wave 7, controlling for age, sex, years of education, global cognition, CVR scores, arthritis, and vision impairment. Given that these analyses involving the three AAQ-SF subscales are exploratory in nature, p-value adjustment was not implemented. The level of significance was set to p < 0.05 (two-sided).
All analyses were conducted in IBM SPSS Statistics 28. Prior to regression modelling, assumptions for linear regression were evaluated, including normality of residuals, linearity, homoscedasticity, and multicollinearity. Variance Inflation Factors (VIFs) were computed for all predictors and found to be below 2.0.
Covariates were selected based on the prior literature and theoretical models indicating their influence on both ageing attitudes and functional ability, including age, sex, years of education, global cognition (ACE-III), cardiovascular disease burden, arthritis, and visual impairment [41].
This article was written using Microsoft Word Office 2024.

3. Results

At wave 4 (baseline), there were 708 participants; 6 years later, at wave 7, 537 were lost to follow-up. Compared with the present study’s sample, participants lost to follow-up were older, had fewer years of education, worse cognition, greater incidence of visual impairment, more depressive symptoms, and worse IADL at baseline (see Appendix A Table A1). Of the 315 participants included in wave 7, 143 were not administered the AAQ-SF questionnaire. Compared with those who completed the AAQ-SF, participants who did not complete the AAQ-SF were older, had fewer years of education, worse cognition, more depressive symptoms, and more functional impairment at baseline (see Appendix A Table A2). Of the 172 participants who completed the AAQ-SF, 20 participants were not included in the GDS-15 linear regressions, 37 participants were not included in the B-ADL linear regressions, and 20 participants were not included in the STAM linear regressions. Compared to those included in the linear regressions, participants who were excluded from those analyses did not have any significant demographic differences at baseline (see Appendix A Table A3, Table A4 and Table A5).
For the Physical Change AAQ-SF subscale, participants had a mean score of 3.60, an SD of 0.81, and a range of 1.25–5.00. For the Psychosocial Change AAQ-SF subscale, participants had a mean score of 3.23, an SD of 1.00, and a range of 1.00–5.00. For the Psychological Growth AAQ-SF subscale, participants had a mean score of 4.00, an SD of 0.83, and a range of 1.00–5.00.
Table 1 displays Spearman correlations between AAQ-SF scores at wave 7 and GDS-15, B-ADL, and STAM scores at wave 4 and wave 7. Physical Change AAQ-SF subscale scores were significantly and negatively correlated with GDS-15 (ρ = −0.282, p < 0.001) at wave 4 and wave 7 (ρ = −0.155, p = 0.049), and significantly, positively correlated with the STAM (ρ = 0.229, p = 0.014) at wave 7. Psychosocial Change AAQ-SF subscale scores were significantly and negatively correlated with GDS-15 (ρ = −0.189, p = 0.014) at wave 4. Psychological Growth AAQ-SF subscale scores were significantly and negatively associated with GDS-15 (ρ = −0.152, p = 0.049) at wave 4.
Table 2 displays the regression results examining the relationship between baseline GDS-15 and wave 7 Physical Change AAQ-SF subscale scores, controlling for covariates in Step 1. After adjusting for all covariates, GDS-15 significantly predicted Physical Change AAQ-SF subscale scores (B = −0.10, 95%CI −0.18 to −0.02, p = 0.021), accounting for 3.3% of additional variance. Wave 7 Physical Change AAQ-SF subscale scores were not significantly associated with B-ADL (B = −0.19, 95%CI −0.42 to 0.03, p = 0.091) and STAM scores at baseline (B = 0.00, 95%CI −0.04 to 0.04, p = 0.946). Detailed results are summarised in the Appendix A Table A6 and Table A7.
Table 3 displays the regression results examining the relationship between baseline B-ADL and wave 7 Psychosocial Change AAQ-SF subscale scores, controlling for covariates at Step 1. After controlling for all covariates, B-ADL significantly predicted Psychosocial Change AAQ-SF subscale scores (B = −0.36, 95%CI −0.64 to −0.09, p = 0.010), accounting for 4.7% of the additional variance. Wave 7 Psychosocial Change AAQ-SF subscale scores were not significantly associated with GDS-15 (B = −0.10, 95%CI −0.21 to 0.01, p = 0.071) and STAM scores at baseline (B = −0.04, 95%CI −0.09 to 0.01, p = 0.139). Detailed results are summarised in the Appendix A Table A8 and Table A9.
Table 4 displays the regression results examining the relationship between baseline GDS-15 and wave 7 Psychological Growth AAQ-SF subscale scores, controlling for covariates at Step 1. After controlling for all covariates, GDS-15 significantly predicted Psychological Growth AAQ-SF subscale scores (B = −0.09, 95%CI −0.17 to −0.01, p = 0.037), accounting for 2.8% of additional variance. Wave 7 Psychological Growth AAQ-SF subscale scores were not significantly associated with B-ADL (B = −0.10, 95%CI −0.30 to 0.10, p = 0.340) and STAM scores at baseline (B = −0.03, 95%CI −0.07 to 0.01, p = 0.113). Detailed results are summarised in the Appendix A Table A10 and Table A11.

4. Discussion

This study aimed to examine the cross-sectional and prospective associations between depressive symptoms, informant-reported and performance-based IADL, and ATA 6 years later in a community-dwelling sample of older adults.
The correlations between AAQ-SF subscales, depressive symptoms, and IADL (informant-report and performance-based) showed that depressive symptoms were associated with worse attitudes towards physical change cross-sectionally. These results are in line with the literature, which has also demonstrated that attitudes towards physical change are associated with depressive symptoms [12,42] and diagnosed depression [43]. One interpretation of these results may be that the Physical Change subscales of the AAQ-SF assess concepts similar to those captured by the GDS-15, such as energy levels. In contrast to previous research [12,42,43], this study found that attitudes towards psychosocial change and psychological growth were not significantly associated with depressive symptoms cross-sectionally. However, the three studies that found this relationship to be significant used the full 24-item AAQ to measure ATA, meaning the Psychosocial Change (i.e., Psychosocial Loss) and Psychological Growth subscales contained four additional questions each compared with the AAQ-SF. The additional questions in the full AAQ may better capture attitudes in both the Psychosocial Change and Psychological Growth subscale, and excluding these may explain the lack of cross-sectional associations with depression found in this study. Other explanations may be that studies where a significant association between Psychosocial Change and Psychological Growth and depression were found to have larger [12,42,43] and younger samples [43] compared with the present study.
This study also found that more negative attitudes towards physical change were associated with worse performance-based IADL cross-sectionally. The Physical Change subscale asks about things that would be affected by functional difficulties, such as exercising, perceptions of health, energy, and feeling old. These functional difficulties may be more likely to be captured by a performance-based measure of IADL compared with the subjective informant-reported IADL measure. Finally, neither measure of IADL was associated with Psychosocial Change or Psychological Growth scores cross-sectionally. The lack of associations could be due to these subscales measuring concepts not directly affected by functional impairment. Previous research on the associations between IADL and AAQ scores did not examine AAQ subscales, nor did they examine the differences in these associations between performance-based and informant-reported IADL measures [11], meaning these results are novel and should be replicated in future studies with larger samples.
This study showed that more depressive symptoms at baseline were associated with more negative perceived physical change and less perceived psychological growth after 6 years. This finding is consistent with other studies that have shown associations between depression and negative ageing attitudes longitudinally [17,19]. Indeed, depressive symptoms may contribute to more negative perceptions of physical health and less positive perceptions of psychological growth, as well as ageing, as depression has been linked to worse quality of life both cross-sectionally and over time [44], and as an extension, depression could also affect perceptions of the ageing process. Baseline depressive symptoms were not significantly associated with more perceived psychosocial loss, which may have been due to the Psychosocial Change subscale containing items such as “I feel excluded from things because of my age”, which may be affected more by a person’s social climate and its inclusivity and attitudes towards older people, than a person’s depressive symptoms.
More informant-reported functional decline at baseline was associated with more negative self-perceptions of psychosocial change after 6 years. Interestingly, informant-reported functional decline was not significantly associated with self-perceptions of psychological growth. This suggests that psychosocial change and psychological growth, while theoretically related, may represent distinct concepts of ageing for older adults. Additionally, it was notable that informant-reported functional changes were not linked to self-reported physical changes despite many studies demonstrating a strong association between physical disability and poorer self-reported functional ability [45,46,47,48]. This discrepancy may be due to our control of key physical covariates (e.g., arthritis and vision impairment) known to impact IADL performance [37,38] in our analysis, or it may be due to using an informant-reported IADL measure, as informants may have less insight into subtle functional and physical changes that a self-reported measure may capture. While several studies have shown that IADL impairment is associated with negative ATA cross-sectionally [11,49], only one study by Kwak et al. [50] has investigated whether IADL is related to ATA longitudinally. Kwak et al. found that more hours of functional care, a proxy measure of IADL impairment, were related to more negative ATA over time. Further, our finding that informant-reported IADL was significantly predictive of psychosocial change, while depressive symptoms were not, is novel and suggests that while IADL and depression are related [51,52] and they predict each other over time [53,54], IADL impairment may be related to future ATA, or at least attitudes towards psychosocial change through a mechanism unrelated to mood.
A surprising finding from this study was that while self-reported GDS-15 and informant-reported IADL were related to the various AAQ-SF subscales, performance-based IADL scores were not. This could be because the AAQ-SF, the GDS-15, and the Bayer-IADL are all subjective measures, whereas the STAM is not. Further, studies have shown that informant-reported IADLs are known to be impacted by participants’ moods and personalities, while performance-based measures are not [55]. Another methodological explanation may be that at baseline, participants who completed the performance-based IADL were highly functioning and largely showed little to no objective functional impairment on the STAM. This is compared to a much larger range of scores reported by the informant on the B-ADL. As such, the non-significant result could be due to the limited variance of STAM scores at baseline.
These findings highlight the clinical and public health relevance of addressing ageing attitudes as modifiable risk factors in later life. Evidence suggests that negative attitudes toward ageing are linked to poorer psychological well-being, increased disability, and accelerated cognitive decline [1,11]. Our results indicate that depressive symptoms and informant-reported functional limitations—both potentially modifiable—are key predictors of less adaptive ageing attitudes. These findings support the value of early interventions targeting both psychological health and everyday function, using approaches such as cognitive behavioural therapy, social prescribing, or functional reablement to foster more positive self-perceptions of ageing [56,57].
Several limitations of the current study should be considered. Firstly, the original MAS sample is not representative of the general older Australian population. MAS participants were highly educated, community-dwelling, overwhelmingly Caucasian, and fluent in English. Secondly, the attrition during the present study’s 6-year follow-up was non-random. Participants lost to follow-up were older, had fewer years of education, and had worse psychological and physical functioning. Thirdly, ATA was the main outcome variable of this study but was only measured once, at wave 7, meaning that examining change in ATA over time was not possible. Further, the AAQ-SF was administered midway through wave 7 as an optional questionnaire sent to participants, meaning it is possible only the healthier participants completed it. Indeed, out of the already biased and healthier wave 7 participants, those who completed the AAQ-SF were younger, had more years of education, and were cognitively, psychologically, and physically healthier. Fourthly, depressive symptoms and ATA were assessed through self-reported measures and thus are susceptible to self-report bias; that is, participants may underreport or overreport depressive symptoms or ATA due to a range of factors, including cognitive decline [58]. Finally, the STAM tool—while a validated performance-based IADL assessment—may have been limited by ceiling effects in our high-functioning sample, potentially underestimating associations with ageing attitudes. This study also excluded participants who had dementia at baseline (wave 4), meaning they could not, by definition, have major impairments in IADL, which likely contributed further to the restricted range of STAM scores.
This study’s strengths include the relatively long follow-up period of 6 years. Other strengths include a well-characterised sample, comprehensive neuropsychological testing, medical history, questionnaires, and a medical exam, which were considered in consensus diagnoses made by a panel of experts. Further, this is the only study to examine the relationships between both a performance-based and informant-reported IADL measure, depression, and attitudes towards ageing. This study also included arthritis and vision impairment as potential confounding variables, which are not often controlled for, meaning that IADL function may be more representative of functional decline that is not due to physical disability.

5. Conclusions

This study shows that depressive symptoms were associated with worse future ageing attitudes towards physical change and psychological growth, while informant-based IADL was associated with future attitudes towards psychosocial change. Given that IADL, depressive symptoms, and ATA are related to the progression to dementia and that each of these factors is also modifiable, there is great merit in understanding the complex and potentially bi-directional relationships between these variables. Together, these results highlight the importance of assessing depressive symptoms and capturing informant-reported functional decline, as these are significantly associated with worse attitudes about the ageing process, a known risk factor of worse health outcomes, including dementia. A life course approach of interventions targeting depression and functional decline early may improve ageing attitudes and thus the health of older adults, therefore reducing the lifetime risk of dementia.

Author Contributions

Conceptualisation, K.N. and S.R.; data curation, K.N. and B.C.P.L.; formal analysis, J.S. and B.C.P.L.; methodology, K.N., B.C.P.L. and S.R.; supervision, K.N., B.C.P.L. and S.R.; validation, J.S., K.N. and B.C.P.L.; visualization, J.S. and K.N.; writing—original draft, J.S.; Writing—review and editing, J.S., K.N., B.C.P.L. and S.R. All authors have read and agreed to the published version of the manuscript.

Funding

This work was supported by three successful National Health & Medical Research Council of Australia Program Grants, grant numbers ID350833, ID568969, and APP1093083, which funded the Sydney Memory and Ageing Study. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. The authors have had full control of all the primary data.

Institutional Review Board Statement

The study was conducted in accordance with the Declaration of Helsinki and approved by the Human Research Ethics Committee of the University of New South Wales (HC: 05037, 09382, 14327, 190962), approval dates: 20 January 2020 to 19 January 2025.

Informed Consent Statement

Informed consent was obtained from all subjects involved in the study.

Data Availability Statement

The datasets that support the findings of this study are not publicly available due to the terms of consent for research participation stipulating that an individual’s data can only be shared outside of the MAS investigators group if the group has reviewed and approved the proposed secondary use of the data. This consent applies regardless of whether data have been de-identified. Access to the datasets is mediated via a standardised request process managed by the CHeBA Research Bank, which can be contacted at ChebaData@unsw.edu.au.

Acknowledgments

The Sydney Memory and Ageing Study, conducted by the Centre for Healthy Brain Ageing (CHeBA), began in 2005. We gratefully acknowledge the participants and staff of the Sydney Memory and Ageing Study.

Conflicts of Interest

The authors declare no conflicts of interest. The funders had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript; or in the decision to publish the results.

Abbreviations

The following abbreviations are used in this manuscript:
AAQAttitudes to Ageing Questionnaire
AAQ-SFAttitudes to Ageing Questionnaire, Short Form
ADAlzheimer’s Disease
ATAAttitudes towards Ageing
BADLBasic Activities of Daily Living
B-ADLBayer’s Activities of Daily Living
CFAConfirmatory Factor Analysis
CNCognitively Normal
CVRCardiovascular Risk
DSM-IVDiagnostic and Statistical Manual of Mental Disorders, Fourth Edition
GDS-1515-item Geriatric Depression Scale
IADLInstrumental Activities of Daily Living
MASSydney Memory and Ageing Study
MCIMild Cognitive Impairment
STAMSydney Test of Activities of Daily Living in Memory Disorders

Appendix A

Table A1. Comparison of analysis sample and excluded wave 4 sample, using wave 4 data.
Table A1. Comparison of analysis sample and excluded wave 4 sample, using wave 4 data.
VariablesAAQ-SF Completers at Wave 7
(n = 171 *)
Wave 4 Participants, Not Included in Wave 7
(n = 537)
t/χ2 ap-Value
Age, years, mean, (SD)81.23 (3.63)84.35 (4.65)t = 8.024<0.001
Sex χ2 = 2.2870.130
 Males, n (%)68 (39.8)249 (46.4)
 Females, n (%)103 (60.2)288 (53.6)
Education, years, mean (SD)12.56 (3.45)11.57 (3.52)t = −3.246<0.001
Global cognition, mean (SD)0.19 (1.02)−0.84 (1.39)t = −8.821<0.001
CVR score, mean (SD)2.75 (3.43)3.28 (3.18)t = 1.6810.094
Arthritis, n (%)94 (55.0)252 (46.9)χ2 = 1.7760.183
Visual impairment, n (%)15 (8.8)85 (15.8)χ2 = 6.2120.013
GDS score, mean (SD)2.02 (1.65)3.23 (2.58)t = 5.687<0.001
B-ADL score, mean (SD)1.52 (0.63)2.32 (1.63)t = 5.842<0.001
STAM score, mean (SD)31.95 (4.03)27.99 (6.30)t = −7.356<0.001
AAQ-SF, Attitudes towards Ageing Questionnaire (Short Form); SD, standard deviation; CVR, Cardiovascular Risk (Framingham); GDS, Geriatric Depression Scale (15-item version); B-ADL, Bayer-Activities of Daily Living Scale; STAM, Sydney Test of Activities of Daily Living in Memory Disorders. * 1 participant was assessed at wave 7 but not at wave 4, so information on their baseline (wave 4) variables is not available. a Independent-samples t tests for continuous variables, and χ2 tests for categorical variables.
Table A2. Comparison of completers and non-completers of AAQ-SF at wave 7, using wave 7 data.
Table A2. Comparison of completers and non-completers of AAQ-SF at wave 7, using wave 7 data.
VariablesAAQ-SF Completers at Wave 7
(n = 172)
AAQ-SF Non-Completers at Wave 7
(n = 143)
t/χ2 ap-Value
Age, years, mean, (SD)81.19 (3.6)82.88 (4.0)t = 3.847<0.001
Sex χ2 = 1.1960.274
 Males, n (%)68 (39.5)48 (33.6)
 Females, n (%)104 (60.5)95 (66.4)
Education, years, mean (SD)12.54 (3.5)11.45 (3.3)t = −2.8510.005
Global cognition, mean (SD)0.19 (1.0)−0.46 (1.1)t = −5.266<0.001
CVR score, mean (SD)2.75 (3.4)3.15 (3.4)t = 0.9670.334
Arthritis, n (%)94 (54.7)82 (57.3)χ2 = 0.3540.552
Visual impairment, n (%)15 (8.7)22 (15.4)χ2 = 3.3790.066
GDS score, mean (SD)2.67 (2.2)2.67 (2.2)t = 2.8120.005
B-ADL score, mean (SD)1.52 (0.6)2.06 (1.3)t = 4.333<0.001
STAM score, mean (SD)31.95 (4.0)29.68 (4.6)t = −4.361<0.001
AAQ-SF, Attitudes towards Ageing Questionnaire (Short Form); SD, standard deviation; CVR, Cardiovascular Risk (Framingham); GDS, Geriatric Depression Scale (15-item version); B-ADL, Bayer-Activities of Daily Living Scale; STAM, Sydney Test of Activities of Daily Living in Memory Disorders. a Independent-samples t tests for continuous variables, and χ2 tests for categorical variables.
Table A3. Comparison of AAQ-SF completer participants included and excluded for GDS-15 regressions, using wave 4 data.
Table A3. Comparison of AAQ-SF completer participants included and excluded for GDS-15 regressions, using wave 4 data.
VariablesAAQ-SF Completer Participants Included in GDS-15 Regressions
(n = 152)
AAQ-SF Completer Participants Not Included in GDS-15 Regressions
(n = 20)
t/χ2 ap-Value
Age, years, mean, (SD)80.99 (3.54)83.11 (3.89)t = 2.4260.566
Sex χ2 = 0.1950.659
 Males, n (%)61 (40.1)7 (35.0)
 Females, n (%)91 (59.9)13 (65.0)
Education, years, mean (SD)12.66 (3.52)11.61 (2.75)t = −1.2810.146
Global cognition, mean (SD)0.22 (1.02)−0.10 (0.95) bt = −1.1210.464
CVR score, mean (SD)2.77 (3.42)2.00 (4.32) ct = −0.4420.805
Arthritis, n (%)89 (58.6)5 (29.4) dχ2 = 5.2600.221
Visual impairment, n (%)12 (1.32)3 (16.7) eχ2 = 1.5390.215
GDS-15 score, mean (SD)1.95 (1.57)2.63 (2.25) ft = 1.5970.277
AAQ-SF, Attitudes towards Ageing Questionnaire (Short Form); SD, standard deviation; CVR, Cardiovascular Risk (Framingham); GDS, Geriatric Depression Scale (15-item version). a Independent-samples t tests for continuous variables, and χ2 tests for categorical variables. b 6 participants were missing data for Global cognition. c 16 participants were missing data for CVR score. d 3 participants were missing data for Arthritis status. e 2 participants were missing data for Visual impairment status. f 3 participants were missing data for GDS-15 score.
Table A4. Comparison of AAQ-SF completer participants included and excluded for B-ADL regressions, using wave 4 data.
Table A4. Comparison of AAQ-SF completer participants included and excluded for B-ADL regressions, using wave 4 data.
VariablesAAQ-SF Completer Participants Included in B-ADL Regressions
(n = 135)
AAQ-SF Completer Participants Not Included in B-ADL Regressions
(n = 37)
t/χ2 ap-Value
Age, years, mean, (SD)80.93 (3.58)82.36 (3.63)t = 2.1310.673
Sex χ2 = 0.8110.368
 Males, n (%)51 (37.8)17 (45.9)
 Females, n (%)84 (62.2)20 (54.1)
Education, years, mean (SD)12.74 (3.52)11.82 (3.11)t = −1.4420.262
Global cognition, mean (SD)0.21 (0.98)0.11 (1.18) bt = −0.4910.159
CVR score, mean (SD)2.79 (3.42)2.52 (3.57) ct = −0.3240.662
Arthritis, n (%)79 (58.5)15 (40.5) dχ2 = 2.2820.131
Visual impairment, n (%)11 (8.1)4 (10.8) eχ2 = 0.3720.542
B-ADL score, mean (SD)1.52 (0.64)1.52 (0.63) ft = 0.0220.391
AAQ-SF, Attitudes towards Ageing Questionnaire (Short Form); SD, standard deviation; CVR, Cardiovascular Risk (Framingham); B-ADL, Bayer-Activities of Daily Living Scale. a Independent-samples t tests for continuous variables, and χ2 tests for categorical variables. b 6 participants were missing data for Global cognition. c 16 participants were missing data for CVR score. d 3 participants were missing data for Arthritis status. e 2 participants were missing data for Visual impairment status. f 13 participants were missing data for B-ADL score.
Table A5. Comparison of AAQ-SF completer participants included and excluded for STAM regressions, using wave 4 data.
Table A5. Comparison of AAQ-SF completer participants included and excluded for STAM regressions, using wave 4 data.
VariablesAAQ-SF Completer Participants Included in STAM Regressions
(n = 152)
AAQ-SF Completer Participants Not Included in STAM Regressions
(n = 20)
t/χ2 ap-Value
Age, years, mean, (SD)80.95 (3.50)83.47 (3.91)t = 2.9240.540
Sex χ2 = 0.1950.659
 Males, n (%)61 (40.1)7 (35.0)
 Females, n (%)91 (59.9)13 (65.0)
Education, years, mean (SD)12.61 (3.47)12.01 (3.33)t = −0.7260.704
Global cognition, mean (SD)0.23 (1.02)−0.17 (0.99) bt = −1.3930.745
CVR score, mean (SD)2.80 (3.41)1.00 (4.16) ct = −1.0330.795
Arthritis, n (%)88 (57.9)6 (30.0) dχ2 = 3.1640.075
Visual impairment, n (%)12 (7.9)3 (15.0) eχ2 = 1.5390.215
STAM score, mean (SD)31.94 (4.10)32.14 (2.04) ft = 0.1290.821
AAQ-SF, Attitudes towards Ageing Questionnaire (Short Form); SD, standard deviation; CVR, Cardiovascular Risk (Framingham); STAM, Sydney Test of Activities of Daily Living in Memory Disorders. a Independent-samples t tests for continuous variables, and χ2 tests for categorical variables. b 6 participants were missing data for Global cognition. c 16 participants were missing data for CVR score. d 3 participants were missing data for Arthritis status. e 2 participants were missing data for Visual impairment status. f 13 participants were missing data for STAM score.
Table A6. Linear regression of B-ADL predicting Physical Change AAQ-SF subscale scores at wave 7 (n = 135).
Table A6. Linear regression of B-ADL predicting Physical Change AAQ-SF subscale scores at wave 7 (n = 135).
VariablesBS.E. B95% CI for BβpR2ΔR2
LowerUpper
Step 1 0.0420.110.11
Age−0.030.02−0.070.01−0.140.113
Sex−0.200.15−0.490.10−0.120.195
Education0.030.02−0.010.070.130.181
Global cognition0.050.08−0.100.210.060.506
CVR score−0.030.02−0.070.01−0.110.195
Arthritis−0.160.14−0.440.12−0.100.266
Vision impairment−0.060.26−0.570.44−0.020.808
Step 2 0.0910.130.02
B-ADL score−0.190.11−0.420.03−0.150.091
CVR, Cardiovascular Risk (Framingham); B-ADL, Bayer-Activities of Daily Living Scale.
Table A7. Linear regression of STAM predicting Physical Change AAQ-SF subscale at wave 7 (n = 152).
Table A7. Linear regression of STAM predicting Physical Change AAQ-SF subscale at wave 7 (n = 152).
VariablesBS.E. B95% CI for BβpR2ΔR2
LowerUpper
Step 1 0.0300.100.10
Age−0.030.02−0.070.01−0.150.087
Sex−0.220.14−0.490.06−0.130.119
Education0.040.02−0.000.080.160.075
Global cognition0.010.07−0.140.150.010.937
CVR score−0.030.02−0.070.01−0.120.133
Arthritis−0.080.13−0.340.19−0.050.567
Vision impairment−0.080.25−0.570.40−0.030.738
Step 2 0.9460.100.00
STAM score0.000.02−0.040.040.010.946
CVR, Cardiovascular risk (Framingham); STAM, Sydney Test of Activities of Daily Living in Memory Disorders.
Table A8. Linear regression of GDS-15 predicting Psychosocial Change AAQ-SF subscale scores at wave 7 (n = 152).
Table A8. Linear regression of GDS-15 predicting Psychosocial Change AAQ-SF subscale scores at wave 7 (n = 152).
VariablesBS.E. B95% CI for BβpR2ΔR2
LowerUpper
Step 1 0.0760.080.08
Age−0.010.02−0.060.04−0.020.809
Sex0.520.170.180.860.250.003
Education0.020.03−0.010.080.080.393
Global cognition0.050.09−0.130.220.050.589
CVR score−0.030.02−0.070.02−0.080.315
Arthritis−0.110.17−0.440.22−0.050.519
Vision impairment0.060.31−0.550.670.020.846
Step 2 0.0710.110.02
GDS-15 score−0.100.05−0.210.01−0.150.071
CVR, Cardiovascular Risk (Framingham); GDS-15, 15-item Geriatric Depression Scale.
Table A9. Linear regression of STAM predicting Psychosocial Change AAQ-SF subscale at wave 7 (n = 152).
Table A9. Linear regression of STAM predicting Psychosocial Change AAQ-SF subscale at wave 7 (n = 152).
VariablesBS.E. B95% CI for BβpR2ΔR2
LowerUpper
Step 1 0.1020.080.08
Age−0.010.03−0.060.04−0.030.770
Sex0.500.180.150.840.240.005
Education0.020.03−0.030.070.070.468
Global cognition0.050.09−0.130.230.050.586
CVR score−0.020.03−0.070.03−0.080.344
Arthritis−0.140.17−0.470.20−0.070.425
Vision impairment0.050.31−0.560.670.010.861
Step 2 0.1390.090.01
STAM score−0.040.03−0.090.01−0.150.139
CVR, Cardiovascular risk (Framingham); STAM, Sydney Test of Activities of Daily Living in Memory Disorders.
Table A10. Linear regression of B-ADL predicting Psychological Growth AAQ-SF subscale scores at wave 7 (n = 135).
Table A10. Linear regression of B-ADL predicting Psychological Growth AAQ-SF subscale scores at wave 7 (n = 135).
VariablesBS.E. B95% CI for BβpR2ΔR2
LowerUpper
Step 1 0.0380.110.11
Age−0.020.02−0.050.02−0.090.332
Sex−0.140.13−0.410.12−0.100.283
Education−0.050.02−0.09−0.01−0.250.007
Global cognition0.060.07−0.080.200.090.368
CVR score−0.040.02−0.08−0.00−0.190.034
Arthritis−0.150.13−0.400.10−0.100.240
Vision impairment0.250.23−0.200.690.090.283
Step 2 0.3400.120.01
B-ADL score−0.100.10−0.300.10−0.080.340
CVR, Cardiovascular risk (Framingham); B-ADL, Bayer-Activities of Daily Living Scale.
Table A11. Linear regression of STAM predicting Psychological Growth AAQ-SF subscale at wave 7 (n = 152).
Table A11. Linear regression of STAM predicting Psychological Growth AAQ-SF subscale at wave 7 (n = 152).
VariablesBS.E. B95% CI for BβpR2ΔR2
LowerUpper
Step 1 0.2190.060.06
Age−0.010.02−0.050.03−0.050.583
Sex−0.040.14−0.310.23−0.030.749
Education−0.040.02−0.080.01−0.150.090
Global cognition0.010.07−0.130.150.010.892
CVR score−0.040.02−0.08−0.01−0.200.023
Arthritis−0.040.13−0.300.22−0.030.765
Vision impairment0.330.24−0.140.810.110.170
Step 2 0.1130.080.02
STAM score−0.030.02−0.070.01−0.170.113
CVR, Cardiovascular risk (Framingham); STAM, Sydney Test of Activities of Daily Living in Memory Disorders.

References

  1. Tully-Wilson, C.; Bojack, R.; Millear, P.M.; Stallman, H.M.; Allen, A.; Mason, J. Self-perceptions of ageing: A systematic review of longitudinal studies. Psychol. Aging 2021, 36, 773–789. [Google Scholar] [CrossRef] [PubMed]
  2. Westerhof, G.J.; Nehrkorn-Bailey, A.M.; Tseng, H.-Y.; Brothers, A.; Siebert, J.S.; Wurm, S.; Wahl, H.-W.; Diehl, M. Longitudinal effects of subjective aging on health and longevity: An updated meta-analysis. Psychol. Aging 2023, 38, 147. [Google Scholar] [CrossRef] [PubMed]
  3. Nichols, E.; Abd-Allah, F.; Abdoli, A.; Abosetugn, A.E.; Abrha, W.A.; Abualhasan, A.; Abu-Gharbieh, E.; Akinyemi, R.O.; Alahdab, F. Global mortality from dementia: Application of a new method and results from the Global Burden of Disease Study 2019. Alzheimer’s Dement. Transl. Res. Clin. Interv. 2021, 7, e12200. [Google Scholar]
  4. Livingston, G.; Huntley, J.; Sommerlad, A.; Ames, D.; Ballard, C.; Banerjee, S.; Brayne, C.; Burns, A.; Cohen-Mansfield, J.; Cooper, C. Dementia prevention, intervention, and care: 2020 report of the Lancet Commission. Lancet 2020, 396, 413–446. [Google Scholar] [CrossRef]
  5. Kornadt, A.E.; Kessler, E.-M.; Wurm, S.; Bowen, C.E.; Gabrian, M.; Klusmann, V. Views on Ageing-A Lifespan Approach. Eur. J. Ageing 2020, 17, 387–401. [Google Scholar] [CrossRef]
  6. Diehl, M.; Wahl, H.-W.; Brothers, A.; Miche, M. Subjective aging and awareness of aging: Toward a new understanding of the aging self. Annu. Rev. Gerontol. Geriatr. 2015, 35, 1–28. [Google Scholar] [CrossRef]
  7. Cai, H.; Jin, Y.; Liu, R.; Zhang, Q.; Su, Z.; Ungvari, G.S.; Tang, Y.-L.; Ng, C.H.; Li, X.-H.; Xiang, Y.-T. Global prevalence of depression in older adults: A systematic review and meta-analysis of epidemiological surveys. Asian J. Psychiatry 2023, 80, 103417. [Google Scholar] [CrossRef]
  8. World Health Organization. The Global Network for Age-Friendly Cities and Communities: Looking Back over the Last Decade, Looking Forward to the Next; World Health Organization: Geneva, Switzerland, 2018. [Google Scholar]
  9. Laidlaw, K.; Kishita, N.; Shenkin, S.D.; Power, M.J. Development of a short form of the Attitudes to Ageing Questionnaire (AAQ). Int. J. Geriatr. Psychiatry 2018, 33, 113–121. [Google Scholar] [CrossRef]
  10. Spuling, S.M.; Klusmann, V.; Bowen, C.E.; Kornadt, A.E.; Kessler, E.-M. The uniqueness of subjective ageing: Convergent and discriminant validity. Eur. J. Ageing 2020, 17, 445–455. [Google Scholar] [CrossRef]
  11. Warmoth, K.; Tarrant, M.; Abraham, C.; Lang, I.A. Older adults’ perceptions of ageing and their health and functioning: A systematic review of observational studies. Psychol. Health Med. 2016, 21, 531–550. [Google Scholar] [CrossRef]
  12. Kisvetrová, H.; Herzig, R.; Bretšnajdrová, M.; Tomanová, J.; Langová, K.; Školoudík, D. Predictors of quality of life and attitude to ageing in older adults with and without dementia. Aging Ment. Health 2021, 25, 535–542. [Google Scholar] [CrossRef]
  13. Bergland, A.; Nicolaisen, M.; Thorsen, K. Predictors of subjective age in people aged 40–79 years: A five-year follow-up study. The impact of mastery, mental and physical health. Aging Ment. Health 2014, 18, 653–661. [Google Scholar] [CrossRef] [PubMed]
  14. Hwang, Y.; Hong, G.-R.S. Predictors of subjective age in community-dwelling older adults in Korea. Geriatr. Nurs. 2019, 40, 314–319. [Google Scholar] [CrossRef] [PubMed]
  15. Chan, J.Y.; Yiu, K.K.; Kwok, T.C.; Wong, S.Y.; Tsoi, K.K. Depression and antidepressants as potential risk factors in dementia: A systematic review and meta-analysis of 18 longitudinal studies. J. Am. Med. Dir. Assoc. 2019, 20, 279–286.e271. [Google Scholar] [CrossRef]
  16. Freeman, A.T.; Santini, Z.I.; Tyrovolas, S.; Rummel-Kluge, C.; Haro, J.M.; Koyanagi, A. Negative perceptions of ageing predict the onset and persistence of depression and anxiety: Findings from a prospective analysis of the Irish Longitudinal Study on Ageing (TILDA). J. Affect. Disord. 2016, 199, 132–138. [Google Scholar] [CrossRef] [PubMed]
  17. Sabatini, S.; Siebert, J.S.; Diehl, M.; Brothers, A.; Wahl, H.-W. Identifying predictors of self-perceptions of aging based on a range of cognitive, physical, and mental health indicators: Twenty-year longitudinal findings from the ILSE study. Psychol. Aging 2021, 37, 486–502. [Google Scholar] [CrossRef]
  18. Segel-Karpas, D.; Cohn-Schwartz, E.; Ayalon, L. Self-perceptions of aging and depressive symptoms: The mediating role of loneliness. Aging Ment. Health 2021, 26, 1495–1501. [Google Scholar] [CrossRef]
  19. Schönstein, A.; Dallmeier, D.; Denkinger, M.; Rothenbacher, D.; Klenk, J.; Bahrmann, A.; Wahl, H.-W. Health and subjective views on aging: Longitudinal findings from the ActiFE Ulm Study. J. Gerontol. Ser. B Psychol. Sci. Soc. Sci. 2021, 76, 1349–1359. [Google Scholar] [CrossRef]
  20. Sikkes, S.A.; de Lange-de Klerk, E.S.; Pijnenburg, Y.A.; Gillissen, F.; Romkes, R.; Knol, D.L.; Uitdehaag, B.M.; Scheltens, P. A new informant-based questionnaire for instrumental activities of daily living in dementia. Alzheimer’s Dement. 2012, 8, 536–543. [Google Scholar] [CrossRef]
  21. Di Carlo, A.; Baldereschi, M.; Lamassa, M.; Bovis, F.; Inzitari, M.; Solfrizzi, V.; Panza, F.; Galluzzo, L.; Scafato, E.; Inzitari, D. Daily function as predictor of dementia in cognitive impairment, no dementia (CIND) and mild cognitive impairment (MCI): An 8-year follow-up in the ILSA study. J. Alzheimer’s Dis. 2016, 53, 505–515. [Google Scholar] [CrossRef]
  22. Cloutier, S.; Chertkow, H.; Kergoat, M.J.; Gélinas, I.; Gauthier, S.; Belleville, S. Trajectories of decline on instrumental activities of daily living prior to dementia in persons with mild cognitive impairment. Int. J. Geriatr. Psychiatry 2021, 36, 314–323. [Google Scholar] [CrossRef] [PubMed]
  23. Reppermund, S.; Brodaty, H.; Crawford, J.; Kochan, N.; Draper, B.; Slavin, M.; Trollor, J.; Sachdev, P. Impairment in instrumental activities of daily living with high cognitive demand is an early marker of mild cognitive impairment: The Sydney memory and ageing study. Psychol. Med. 2013, 43, 2437–2445. [Google Scholar] [CrossRef]
  24. Hindmarch, I.; Lehfeld, H.; de Jongh, P.; Erzigkeit, H. The Bayer activities of daily living scale (B-ADL). Dement. Geriatr. Cogn. Disord. 1998, 9 (Suppl. S2), 20–26. [Google Scholar] [CrossRef]
  25. Reppermund, S.; Birch, R.C.; Crawford, J.D.; Wesson, J.; Draper, B.; Kochan, N.A.; Trollor, J.N.; Luttenberger, K.; Brodaty, H.; Sachdev, P.S. Performance-based assessment of instrumental activities of daily living: Validation of the Sydney Test of Activities of Daily Living in Memory Disorders (STAM). J. Am. Med. Dir. Assoc. 2017, 18, 117–122. [Google Scholar] [CrossRef] [PubMed]
  26. McGarrigle, C.A.; Ward, M.; Kenny, R.A. Negative aging perceptions and cognitive and functional decline: Are you as old as you feel? J. Am. Geriatr. Soc. 2021, 70, 777–788. [Google Scholar] [CrossRef] [PubMed]
  27. Warmoth, K.; Tarrant, M.; Abraham, C.; Lang, I.A. Relationship between perceptions of ageing and frailty in English older adults. Psychol. Health Med. 2018, 23, 465–474. [Google Scholar] [CrossRef]
  28. Chatterji, S.; Byles, J.; Cutler, D.; Seeman, T.; Verdes, E. Health, functioning, and disability in older adults—Present status and future implications. Lancet 2015, 385, 563–575. [Google Scholar] [CrossRef]
  29. Zenebe, Y.; Akele, B.; W/Selassie, M.; Necho, M. Prevalence and determinants of depression among old age: A systematic review and meta-analysis. Ann. Gen. Psychiatry 2021, 20, 55. [Google Scholar] [CrossRef]
  30. Levy, B. Stereotype embodiment: A psychosocial approach to aging. Curr. Dir. Psychol. Sci. 2009, 18, 332–336. [Google Scholar] [CrossRef]
  31. Sachdev, P.S.; Brodaty, H.; Reppermund, S.; Kochan, N.A.; Trollor, J.N.; Draper, B.; Slavin, M.J.; Crawford, J.; Kang, K.; Broe, G.A. The Sydney Memory and Ageing Study (MAS): Methodology and baseline medical and neuropsychiatric characteristics of an elderly epidemiological non-demented cohort of Australians aged 70–90 years. Int. Psychogeriatr. 2010, 22, 1248–1264. [Google Scholar] [CrossRef]
  32. Laidlaw, K.; Power, M.; Schmidt, S. The attitudes to ageing questionnaire (AAQ): Development and psychometric properties. Int. J. Geriatr. Psychiatry 2007, 22, 367–379. [Google Scholar] [PubMed]
  33. Yesavage, J.A.; Brink, T.L.; Rose, T.L.; Lum, O.; Huang, V.; Adey, M.; Leirer, V.O. Development and validation of a geriatric depression screening scale: A preliminary report. J. Psychiatr. Res. 1982, 17, 37–49. [Google Scholar] [PubMed]
  34. Yesavage, J.A.; Sheikh, J.I. Geriatric depression scale (GDS) recent evidence and development of a shorter version. Clin. Gerontol. 1986, 5, 165–173. [Google Scholar] [CrossRef]
  35. Brink, T. Geriatric depression and hypochondriasis: Incidence, interaction, assessment and treatment. Psychother. Theory Res. Pract. 1982, 19, 506. [Google Scholar]
  36. Erzigkeit, H.; Lehfeld, H.; Peña-Casanova, J.; Bieber, F.; Yekrangi-Hartmann, C.; Rupp, M.; Rappard, F.; Arnold, K.; Hindmarch, I. The Bayer-Activities of Daily Living Scale (B-ADL): Results from a validation study in three European countries. Dement. Geriatr. Cogn. Disord. 2001, 12, 348–358. [Google Scholar]
  37. Christ, S.L.; Zheng, D.D.; Swenor, B.K.; Lam, B.L.; West, S.K.; Tannenbaum, S.L.; Muñoz, B.E.; Lee, D.J. Longitudinal relationships among visual acuity, daily functional status, and mortality: The Salisbury Eye Evaluation Study. JAMA Ophthalmol. 2014, 132, 1400–1406. [Google Scholar] [CrossRef]
  38. Stamm, T.A.; Pieber, K.; Crevenna, R.; Dorner, T.E. Impairment in the activities of daily living in older adults with and without osteoporosis, osteoarthritis and chronic back pain: A secondary analysis of population-based health survey data. BMC Musculoskelet. Disord. 2016, 17, 139. [Google Scholar]
  39. Numbers, K.; Lam, B.C.; Crawford, J.D.; Kochan, N.A.; Sachdev, P.S.; Brodaty, H. Increased reporting of subjective cognitive complaints over time predicts cognitive decline and incident dementia. Int. J. Geriatr. Psychiatry 2021, 36, 1739–1747. [Google Scholar] [CrossRef]
  40. D’Agostino Sr, R.B.; Vasan, R.S.; Pencina, M.J.; Wolf, P.A.; Cobain, M.; Massaro, J.M.; Kannel, W.B. General cardiovascular risk profile for use in primary care: The Framingham Heart Study. Circulation 2008, 117, 743–753. [Google Scholar]
  41. Jang, S.; Numbers, K.; Lam, B.C.P.; Sachdev, P.S.; Brodaty, H.; Reppermund, S. Performance-based vs informant-reported instrumental activities of daily living in predicting dementia. J. Am. Med. Dir. Assoc. 2022, 23, 1342–1347.e9. [Google Scholar] [CrossRef]
  42. Janecková, H.; Dragomirecká, E.; Holmerová, I.; Vanková, H. The attitudes of older adults living in institutions and their caregivers to ageing. Cent. Eur. J. Public Health 2013, 21, 63. [Google Scholar] [CrossRef] [PubMed]
  43. Thorpe, A.M.; Pearson, J.F.; Schluter, P.J.; Spittlehouse, J.K.; Joyce, P.R. Attitudes to aging in midlife are related to health conditions and mood. Int. Psychogeriatr. 2014, 26, 2061–2071. [Google Scholar] [CrossRef]
  44. Sivertsen, H.; Bjørkløf, G.H.; Engedal, K.; Selbæk, G.; Helvik, A.-S. Depression and quality of life in older persons: A review. Dement. Geriatr. Cogn. Disord. 2015, 40, 311–339. [Google Scholar] [CrossRef]
  45. Taş, Ü.; Verhagen, A.P.; Bierma-Zeinstra, S.M.; Hofman, A.; Odding, E.; Pols, H.A.; Koes, B.W. Incidence and risk factors of disability in the elderly: The Rotterdam Study. Prev. Med. 2007, 44, 272–278. [Google Scholar] [CrossRef] [PubMed]
  46. Connolly, D.; Garvey, J.; McKee, G. Factors associated with ADL/IADL disability in community dwelling older adults in the Irish longitudinal study on ageing (TILDA). Disabil. Rehabil. 2017, 39, 809–816. [Google Scholar] [PubMed]
  47. Stuck, A.E.; Walthert, J.M.; Nikolaus, T.; Büla, C.J.; Hohmann, C.; Beck, J.C. Risk factors for functional status decline in community-living elderly people: A systematic literature review. Soc. Sci. Med. 1999, 48, 445–469. [Google Scholar]
  48. van der Vorst, A.; Zijlstra, G.R.; Witte, N.D.; Duppen, D.; Stuck, A.E.; Kempen, G.I.; Schols, J.M.; Consortium, D.-S. Limitations in activities of daily living in community-dwelling people aged 75 and over: A systematic literature review of risk and protective factors. PLoS ONE 2016, 11, e0165127. [Google Scholar] [CrossRef]
  49. Wang, G.; Shi, J.; Yao, J.; Fu, H. Relationship between activities of daily living and attitude toward own aging among the elderly in China: A chain mediating model. Int. J. Aging Hum. Dev. 2020, 91, 581–598. [Google Scholar] [CrossRef]
  50. Kwak, M.; Ingersoll-Dayton, B.; Burgard, S. Receipt of care and depressive symptoms in later life: The importance of self-perceptions of aging. J. Gerontol. Ser. B Psychol. Sci. Soc. Sci. 2014, 69, 325–335. [Google Scholar]
  51. Simning, A.; Seplaki, C.L. Association of the cumulative burden of late-life anxiety and depressive symptoms with functional impairment. Int. J. Geriatr. Psychiatry 2020, 35, 80–90. [Google Scholar]
  52. Coventry, P.A.; McMillan, D.; Clegg, A.; Brown, L.; van der Feltz-Cornelis, C.; Gilbody, S.; Ali, S. Frailty and depression predict instrumental activities of daily living in older adults: A population-based longitudinal study using the CARE75+ cohort. PLoS ONE 2020, 15, e0243972. [Google Scholar] [CrossRef] [PubMed]
  53. Chen, C.-M.; Mullan, J.; Su, Y.-Y.; Griffiths, D.; Kreis, I.A.; Chiu, H.-C. The Longitudinal Relationship Between Depressive Symptoms and Disability for Older Adults: A Population-Based Study. J. Gerontol. Ser. A Biomed. Sci. Med. Sci. 2012, 67, 1059–1067. [Google Scholar] [CrossRef] [PubMed]
  54. Lin, I.-F.; Wu, H.-S. Does informal care attenuate the cycle of ADL/IADL disability and depressive symptoms in late life? J. Gerontol. Ser. B Psychol. Sci. Soc. Sci. 2011, 66, 585–594. [Google Scholar] [CrossRef] [PubMed]
  55. Numbers, K.; Jang, S.; Brodaty, H.; Sachdev, P.S.; Draper, B.; Reppermund, S. Instrumental activities of daily living by subjective and objective measures: The impact of depression and personality. Front. Aging Neurosci. 2022, 14, 829544. [Google Scholar] [CrossRef]
  56. Hughes, M.L.; Touron, D.R. Aging in context: Incorporating everyday experiences into the study of subjective age. Front. Psychiatry 2021, 12, 633234. [Google Scholar] [CrossRef]
  57. Westerhof, G.J.; Wurm, S. Subjective aging and health. In Oxford Research Encyclopedia of Psychology; Oxford University Press: Oxford, UK, 2018. [Google Scholar]
  58. Bauhoff, S. Systematic self-report bias in health data: Impact on estimating cross-sectional and treatment effects. Health Serv. Outcomes Res. Methodol. 2011, 11, 44–53. [Google Scholar] [CrossRef]
Figure 1. Flowchart of the inclusion and exclusion of participants in the present study. 1 This includes participants who were not assessed, had withdrawn, or were lost to follow-up.
Figure 1. Flowchart of the inclusion and exclusion of participants in the present study. 1 This includes participants who were not assessed, had withdrawn, or were lost to follow-up.
Diagnostics 15 01145 g001
Table 1. Spearman correlation between AAQ-SF, GDS, B-ADL, and STAM.
Table 1. Spearman correlation between AAQ-SF, GDS, B-ADL, and STAM.
Variablen123456789
1. Physical Change AAQ-SF subscale score at wave 7172-
2. Psychosocial Change AAQ-SF subscale score at wave 71720.205 **-
3. Psychological Growth AAQ-SF subscale Score at wave 71720.291 **0.056-
4. GDS-15 at wave 4169−0.282 **−0.189 *−0.152 *-
5. B-ADL score at wave 4149−0.160−0.147−0.0430.274 **-
6. STAM score at wave 41590.1080.032−0.158−0.051−0.235 **-
7. GDS-15 score at wave 7162−0.155 *−0.104−0.0580.249 **−0.001−0.132-
8. B-ADL score at wave 7142−0.119−0.065−0.0410.239 **0.639 **−0.182 *0.133-
9. STAM score at wave 71150.229 *0.0480.006−0.263 **−0.254 *0.440 **−0.347 **−0.370 **-
AAQ-SF, Attitudes towards Ageing Questionnaire (Short Form); GDS-15, 15-item Geriatric Depression Scale; B-ADL, Bayer-Activities of Daily Living Scale; STAM, Sydney Test of Activities of Daily Living in Memory Disorders. * p < 0.05. ** p < 0.01.
Table 2. Linear regression of GDS-15 predicting Physical Change AAQ-SF subscale scores at wave 7 (n = 152).
Table 2. Linear regression of GDS-15 predicting Physical Change AAQ-SF subscale scores at wave 7 (n = 152).
VariablesBSE95% CI for BβpR2ΔR2
LowerUpper
Step 1 0.0380.100.10
Age−0.040.02−0.070.00−0.150.075
Sex−0.200.14−0.470.07−0.120.152
Education0.040.02−0.010.080.150.087
Global cognition0.010.07−0.130.150.020.841
CVR score−0.030.02−0.070.01−0.120.142
Arthritis−0.070.13−0.340.19−0.040.592
Vision impairment−0.070.24−0.550.42−0.020.783
Step 2 0.0210.130.03
GDS-15 score−0.100.04−0.18−0.02−0.190.021
CVR, Cardiovascular Risk (Framingham); GDS-15, 15-item Geriatric Depression Scale.
Table 3. Linear regression of B-ADL predicting Psychosocial Change AAQ-SF subscale scores at wave 7 (n = 135).
Table 3. Linear regression of B-ADL predicting Psychosocial Change AAQ-SF subscale scores at wave 7 (n = 135).
VariablesBSE95% CI for BβpR2ΔR2
LowerUpper
Step 1 0.0810.090.09
Age−0.020.03−0.070.03−0.060.494
Sex0.600.190.230.970.290.002
Education0.010.03−0.040.060.040.703
Global cognition0.040.10−0.160.230.040.705
CVR score−0.010.03−0.060.04−0.030.770
Arthritis−0.160.18−0.520.19−0.080.362
Vision impairment0.210.32−0.420.850.060.505
Step 2 0.0100.140.05
B-ADL score−0.360.14−0.64−0.09−0.230.010
CVR, Cardiovascular Risk (Framingham); B-ADL, Bayer-Activities of Daily Living Scale.
Table 4. Linear regression of GDS-15 predicting Psychological Growth AAQ-SF subscale scores at wave 7 (n = 152).
Table 4. Linear regression of GDS-15 predicting Psychological Growth AAQ-SF subscale scores at wave 7 (n = 152).
VariablesBSE95% CI for BβpR2ΔR2
LowerUpper
Step 1 0.1380.070.07
Age−0.010.02−0.050.02−0.060.460
Sex−0.010.14−0.290.26−0.010.925
Education−0.040.02−0.08−0.00−0.190.039
Global cognition0.030.07−0.110.170.040.635
CVR score−0.040.02−0.08−0.00−0.180.035
Arthritis−0.040.13−0.310.22−0.030.741
Vision impairment0.370.24−0.110.850.120.132
Step 2 0.0370.100.03
GDS-15 score−0.090.04−0.17−0.01−0.180.037
CVR, Cardiovascular Risk (Framingham); GDS-15, 15-item Geriatric Depression Scale.
Disclaimer/Publisher’s Note: The statements, opinions and data contained in all publications are solely those of the individual author(s) and contributor(s) and not of MDPI and/or the editor(s). MDPI and/or the editor(s) disclaim responsibility for any injury to people or property resulting from any ideas, methods, instructions or products referred to in the content.

Share and Cite

MDPI and ACS Style

Sawang, J.; Numbers, K.; Lam, B.C.P.; Reppermund, S. Relationships Between Functional Impairment, Depressive Symptoms, and Ageing Attitudes in Older Adults. Diagnostics 2025, 15, 1145. https://doi.org/10.3390/diagnostics15091145

AMA Style

Sawang J, Numbers K, Lam BCP, Reppermund S. Relationships Between Functional Impairment, Depressive Symptoms, and Ageing Attitudes in Older Adults. Diagnostics. 2025; 15(9):1145. https://doi.org/10.3390/diagnostics15091145

Chicago/Turabian Style

Sawang, Jessica, Katya Numbers, Ben C. P. Lam, and Simone Reppermund. 2025. "Relationships Between Functional Impairment, Depressive Symptoms, and Ageing Attitudes in Older Adults" Diagnostics 15, no. 9: 1145. https://doi.org/10.3390/diagnostics15091145

APA Style

Sawang, J., Numbers, K., Lam, B. C. P., & Reppermund, S. (2025). Relationships Between Functional Impairment, Depressive Symptoms, and Ageing Attitudes in Older Adults. Diagnostics, 15(9), 1145. https://doi.org/10.3390/diagnostics15091145

Note that from the first issue of 2016, this journal uses article numbers instead of page numbers. See further details here.

Article Metrics

Back to TopTop