Follow-Up Infarct Volume Prediction by CTP-Based Hypoperfusion Index, and the Discrepancy between Small Follow-Up Infarct Volume and Poor Functional Outcome—A Multicenter Study
, Siyun Liu 2, Jincheng Wang 3, Lixiang Huang 4, Bin Song 5, Xiaoqiang Tang 6, Boyu Chen 7, Haiting Yang 8, Chengcheng Zhu 9, Ajay Malhotra 10 and Yuting Wang 1,*
Round 1
Reviewer 1 Report
I have already reviewed the article about infarct volume prediction by CTP-based hypoperfusion index and the discrepancy between small follow-up infarct volume and poor functional outcome. The article is well written and organized. The goals, introduction, methods, results are logical. The discussion corresponds with results. I have nothing to add and change. My take on this is that article has to be published in present form.
Reviewer 2 Report
Congratulations for your work
I think your paper is valuable because it helps to go deeper in the understanding of the pathophysiology of the disease and helps as well clinicians to better stratify stroke patients outcome.
The attempt to find an imaging biomarker of the clinical outcome is fascinating even if the sensitivity and specificity of the predictive model need to be improved, as you've clearly shown.
Please, for the sake of clarity, repeat the baseline overall number of patient you've collected (211) at the beginning of the "Results" paragraph.
