Functional and Anatomical Outcomes of Pars Plana Vitrectomy for Epiretinal Membrane in Patients with Uveitis
Abstract
:1. Introduction
2. Materials and Methods
2.1. Study Design, Participants and Ethics
2.2. Data Collection
2.3. Surgical Technique and Perioperative Treatment
2.4. Statistical Analysis
3. Results
3.1. Baseline Characteristics
3.2. Surgical Details
3.3. Visual Outcomes
3.4. Anatomical Outcomes and Treatment
3.5. Uveitis Status and Therapeutic Regimen
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Type, Aetiology | Baseline Tx | Preop Uveitis Status | Postop Active Uveitis | Preop CME | Postop CME | Tx at Final FU | Complications | Preop BCVA | 6-Month BCVA | Final BCVA |
---|---|---|---|---|---|---|---|---|---|---|
panuveitis, sclerouveitis, idiopathic | TS + OS | Inactive | Inactive | Yes | Yes | TS + OS | - | 0.90 | 0.40 | 0.10 |
anterior uveitis, idiopathic | TS + OS | Inactive | Inactive | Yes | Yes | TS | Unstable IOL, anterior capsule phimosis | 0.70 | 1.00 | 1.00 |
posterior uveitis, CMV immune recovery related uveitis | TS + OS | Mild AC inflammation | Mild AC inflammation | Yes | No | TS + OS + IVT ganciclovir | CMV retinitis | 1.50 | 0.70 | 0.80 |
posterior uveitis, CMV immune recovery related uveitis | TS | Mild AC inflammation | Mild AC inflammation | Yes | No | TS | - | 0.50 | 0.40 | 0.40 |
Panuveitis, toxoplasmosis | TS | Marked AC inflammation | Moderate AC inflammation | N/A | Yes | TS | cataract | 1.00 | 0.10 | 0.22 |
Anterior uveitis, idiopathic | TS | Mild AC inflammation | Inactive | Yes | No | TS | - | 0.50 | 0.50 | 0.20 |
Intermediate uveitis | TS | Vitritis | Inactive | Yes | Yes | TS | RD, hypotony | 0.90 | 0.94 | 0.96 |
sympathetic ophthalmia | TS + OS + IFX | Inactive | Inactive | Yes | Yes | TS + OS + IFX | - | 0.80 | 0.08 | 0.40 |
posterior uveitis, sarcoidosis | TS | Mild AC inflammation | Inactive | Yes | No | TS + OS | NVG, occlusive vasculitis | 1.00 | 0.80 | 0.60 |
panuveitis, idiopathic | TS | Moderate AC inflammation | Mild AC inflammation | n/a | No | TS | - | 1.04 | 0.40 | 0.50 |
chronic panuveitis, idiopathic | TS + OS + MTX | Vitritis | Mild AC inflammation | Yes | No | TS + AZT | - | 0.70 | 0.60 | 0.30 |
posterior uveitis, sarcoidosis | TS + OS + MTX | Vitritis | Mild AC inflammation | Yes | Yes | TS + OS + MTX | OHT | 0.50 | 0.40 | 0.30 |
Chronic anterior uveitis | TS | Mild AC inflammation | Inactive | Yes | No | TS | OHT | 0.40 | 0.30 | 0.50 |
Chronic anterior uveitis | TS | Inactive | Inactive | Yes | No | TS | OHT | 0.50 | 0.20 | 0.20 |
Anterior uveitis, HSV | TS | Inactive | Inactive | No | No | TS | - | 0.20 | −0.10 | −0.10 |
Intermediate uveitis, sarcoidosis | OS | Mild AC inflammation | Mild AC inflammation | Yes | Yes | TS + OS | - | 0.76 | 0.48 | 0.20 |
Intermediate uveitis, idiopathic | OS | Inactive | Inactive | Yes | No | OS | - | 0.80 | 0.18 | 0.20 |
Panuveitis, idiopathic | TS | Inactive | Mild AC inflammation | No | No | TS | glaucoma | 1.50 | 1.60 | NPL |
Posterior uveitis, idiopathic | TS | Inactive | Inactive | N/A | No | TS | BRAO | 0.48 | 0.18 | 0.20 |
Posterior uveitis, toxocariasis | - | Inactive | Inactive | Yes | Yes | - | - | 0.80 | 0.80 | 0.80 |
Chronic anterior uveitis, idiopathic | TS | Inactive | Inactive | No | Yes | TS | 0.40 | 0.30 | 0.20 | |
Intermediate uveitis, MS | - | Inactive | Inactive | Yes | Yes | - | - | 0.70 | 0.60 | 0.50 |
anterior uveitis, presumed sarcoidosis | TS | Inactive | Inactive | No | No | TS | glaucoma | 0.50 | 0.10 | 0.30 |
Panuveitis, toxoplasmosis | TS | Inactive | Inactive | No | Yes | TS | glaucoma, PCO | 0.60 | 0.18 | 0.30 |
anterior uveitis, sarcoidosis + TB | - | Inactive | Inactive | No | Yes | PF | 0.80 | 0.48 | 0.90 | |
anterior uveitis, idiopathic | - | Inactive | Inactive | Yes | No | - | - | 0.50 | 0.18 | 0.20 |
Intermediate uveitis, idiopathic | - | Inactive | Inactive | Yes | Yes | - | OHT, FTMH | 0.48 | 0.60 | 0.60 |
Intermediate uveitis, idiopathic | TS | Inactive | Inactive | Yes | No | - | cataract | 0.76 | 0.90 | 0.60 |
posterior uveitis, CMV | - | Inactive | Inactive | Yes | Yes | TS | - | 1.00 | 0.90 | 1.00 |
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Cristescu, I.-E.; Ivanova, T.; Moussa, G.; Ferrara, M.; Patton, N.; Dhawahir-Scala, F.; Ch’ng, S.W.; Mitra, A.; Tyagi, A.K.; Lett, K.S.; et al. Functional and Anatomical Outcomes of Pars Plana Vitrectomy for Epiretinal Membrane in Patients with Uveitis. Diagnostics 2022, 12, 3044. https://doi.org/10.3390/diagnostics12123044
Cristescu I-E, Ivanova T, Moussa G, Ferrara M, Patton N, Dhawahir-Scala F, Ch’ng SW, Mitra A, Tyagi AK, Lett KS, et al. Functional and Anatomical Outcomes of Pars Plana Vitrectomy for Epiretinal Membrane in Patients with Uveitis. Diagnostics. 2022; 12(12):3044. https://doi.org/10.3390/diagnostics12123044
Chicago/Turabian StyleCristescu, Irina-Elena, Tsveta Ivanova, George Moussa, Mariantonia Ferrara, Niall Patton, Felipe Dhawahir-Scala, Soon Wai Ch’ng, Arijit Mitra, Ajai K. Tyagi, Kim Son Lett, and et al. 2022. "Functional and Anatomical Outcomes of Pars Plana Vitrectomy for Epiretinal Membrane in Patients with Uveitis" Diagnostics 12, no. 12: 3044. https://doi.org/10.3390/diagnostics12123044