Next Article in Journal
Serum Levels of Cytokine-Induced Apoptosis Inhibitor 1 (CIAPIN1) as a Potential Prognostic Biomarker of Cholangiocarcinoma
Next Article in Special Issue
Validation and Optimization of Proximal Femurs Microstructure Analysis Using High Field and Ultra-High Field MRI
Previous Article in Journal
Deep Learning-Based Differentiation between Mucinous Cystic Neoplasm and Serous Cystic Neoplasm in the Pancreas Using Endoscopic Ultrasonography
Article

Diagnostic Value of Whole-Body MRI Short Protocols in Bone Lesion Detection in Multiple Myeloma Patients

1
Department of Diagnostic Radiology, “San Gerardo” Hospital, Via Pergolesi 33, 20900 Monza, MB, Italy
2
School of Medicine, University of Milano-Bicocca, Via Cadore 48, 20900 Monza, MB, Italy
3
Department of Diagnostic Radiology, H Papa Giovanni XXIII, Piazza OMS 1, 24127 Bergamo, BG, Italy
*
Author to whom correspondence should be addressed.
Academic Editors: Kyung Sung, Harrison Kim and Fatemeh Zabihollahy
Diagnostics 2021, 11(6), 1053; https://doi.org/10.3390/diagnostics11061053
Received: 13 May 2021 / Revised: 29 May 2021 / Accepted: 4 June 2021 / Published: 8 June 2021
(This article belongs to the Special Issue Advanced Techniques in Body Magnetic Resonance Imaging 2.0)
The aim of the study is to evaluate the effectiveness of short whole-body magnetic resonance imaging (WBMRI) protocols for the overall assessment of bone marrow involvement in patients with multiple myeloma (MM), in comparison with standard whole-body MRI protocol. Patients with biopsy-proven MM, who underwent a WBMRI with full-body coverage (from vertex to feet) were retrospectively enrolled. WBMRI images were independently evaluated by two expert radiologists, in terms of infiltration patterns (normal, focal, diffuse, and combined), according to location (the whole skeleton was divided into six anatomic districts: skull, spine, sternum and ribs, upper limbs, pelvis and proximal two-thirds of the femur, remaining parts of lower limbs) and lytic lesions number (<5, 5–20, and >20). The majority of patients showed focal and combined infiltration patterns with bone lesions predominantly distributed in the spine and pelvis. As skull and lower limbs are less frequently involved by focal bone lesions, excluding them from the standard MRI protocol allows to obtain a shorter protocol, maintaining a good diagnostic value. View Full-Text
Keywords: multiple myeloma; hematologic neoplasms; infiltration pattern; magnetic resonance imaging; diffusion-weighted imaging multiple myeloma; hematologic neoplasms; infiltration pattern; magnetic resonance imaging; diffusion-weighted imaging
Show Figures

Figure 1

MDPI and ACS Style

Ippolito, D.; Giandola, T.; Maino, C.; Gandola, D.; Ragusi, M.; Brambilla, P.; Bonaffini, P.A.; Sironi, S. Diagnostic Value of Whole-Body MRI Short Protocols in Bone Lesion Detection in Multiple Myeloma Patients. Diagnostics 2021, 11, 1053. https://doi.org/10.3390/diagnostics11061053

AMA Style

Ippolito D, Giandola T, Maino C, Gandola D, Ragusi M, Brambilla P, Bonaffini PA, Sironi S. Diagnostic Value of Whole-Body MRI Short Protocols in Bone Lesion Detection in Multiple Myeloma Patients. Diagnostics. 2021; 11(6):1053. https://doi.org/10.3390/diagnostics11061053

Chicago/Turabian Style

Ippolito, Davide, Teresa Giandola, Cesare Maino, Davide Gandola, Maria Ragusi, Paolo Brambilla, Pietro A. Bonaffini, and Sandro Sironi. 2021. "Diagnostic Value of Whole-Body MRI Short Protocols in Bone Lesion Detection in Multiple Myeloma Patients" Diagnostics 11, no. 6: 1053. https://doi.org/10.3390/diagnostics11061053

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop