The Importance of Multimodality Imaging in the Diagnosis and Management of Patients with Infiltrative Cardiomyopathies: An Update

Sascău, Radu; Anghel, Larisa; Clement, Alexandra; Bostan, Mădălina; Radu, Rodica; Stătescu, Cristian

doi:10.3390/diagnostics11020256

Open AccessReview

The Importance of Multimodality Imaging in the Diagnosis and Management of Patients with Infiltrative Cardiomyopathies: An Update

by

Radu Sascău

^1,2,

Larisa Anghel

^1,2,*,

Alexandra Clement

^2,*,

Mădălina Bostan

^1,2,*

,

Rodica Radu

^1,2 and

Cristian Stătescu

^1,2

¹

Internal Medicine Department, “Grigore T. Popa” University of Medicine and Pharmacy, 700503 Iași, Romania

²

Cardiology Department, Cardiovascular Diseases Institute “Prof. Dr. George I.M.Georgescu”, 700503 Iași, Romania

^*

Authors to whom correspondence should be addressed.

Diagnostics 2021, 11(2), 256; https://doi.org/10.3390/diagnostics11020256

Submission received: 28 December 2020 / Revised: 2 February 2021 / Accepted: 4 February 2021 / Published: 7 February 2021

(This article belongs to the Special Issue Role of Imaging Modalities in the Evaluation of Nonischemic Cardiomyopathy)

Download

Browse Figures

Versions Notes

Abstract

Infiltrative cardiomyopathies (ICMs) comprise a broad spectrum of inherited and acquired conditions (mainly amyloidosis, sarcoidosis, and hemochromatosis), where the progressive buildup of abnormal substances within the myocardium results in left ventricular hypertrophy and manifests as restrictive physiology. Noninvasive multimodality imaging has gradually eliminated endomyocardial biopsy from the diagnostic workup of infiltrative cardiac deposition diseases. However, even with modern imaging techniques’ widespread availability, these pathologies persist in being largely under- or misdiagnosed. Considering the advent of novel, revolutionary pharmacotherapies for cardiac amyloidosis, the archetypal example of ICM, a standardized diagnostic approach is warranted. Therefore, this review aims to emphasize the importance of contemporary cardiac imaging in identifying specific ICM and improving outcomes via the prompt initiation of a targeted treatment.

Keywords: infiltrative cardiomyopathies; multimodality imaging; amyloidosis; sarcoidosis; hemochromatosis

Share and Cite

MDPI and ACS Style

Sascău, R.; Anghel, L.; Clement, A.; Bostan, M.; Radu, R.; Stătescu, C. The Importance of Multimodality Imaging in the Diagnosis and Management of Patients with Infiltrative Cardiomyopathies: An Update. Diagnostics 2021, 11, 256. https://doi.org/10.3390/diagnostics11020256

AMA Style

Sascău R, Anghel L, Clement A, Bostan M, Radu R, Stătescu C. The Importance of Multimodality Imaging in the Diagnosis and Management of Patients with Infiltrative Cardiomyopathies: An Update. Diagnostics. 2021; 11(2):256. https://doi.org/10.3390/diagnostics11020256

Chicago/Turabian Style

Sascău, Radu, Larisa Anghel, Alexandra Clement, Mădălina Bostan, Rodica Radu, and Cristian Stătescu. 2021. "The Importance of Multimodality Imaging in the Diagnosis and Management of Patients with Infiltrative Cardiomyopathies: An Update" Diagnostics 11, no. 2: 256. https://doi.org/10.3390/diagnostics11020256

APA Style

Sascău, R., Anghel, L., Clement, A., Bostan, M., Radu, R., & Stătescu, C. (2021). The Importance of Multimodality Imaging in the Diagnosis and Management of Patients with Infiltrative Cardiomyopathies: An Update. Diagnostics, 11(2), 256. https://doi.org/10.3390/diagnostics11020256

Note that from the first issue of 2016, this journal uses article numbers instead of page numbers. See further details here.

Article Menu

The Importance of Multimodality Imaging in the Diagnosis and Management of Patients with Infiltrative Cardiomyopathies: An Update

Abstract

Share and Cite

Article Metrics

Article Access Statistics

Further Information

Guidelines

MDPI Initiatives

Follow MDPI