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Successive Paradigm Shifts in the Bacterial Cell Cycle and Related Subjects

Laboratory of Microbiology Signals and Microenvironment, University of Rouen, 76821 Mont Saint Aignan, France
Received: 6 August 2018 / Revised: 28 February 2019 / Accepted: 4 March 2019 / Published: 7 March 2019
(This article belongs to the Section Hypotheses in the Life Sciences)
A paradigm shift in one field can trigger paradigm shifts in other fields. This is illustrated by the paradigm shifts that have occurred in bacterial physiology following the discoveries that bacteria are not unstructured, that the bacterial cell cycle is not controlled by the dynamics of peptidoglycan, and that the growth rates of bacteria in the same steady-state population are not at all the same. These paradigm shifts are having an effect on longstanding hypotheses about the regulation of the bacterial cell cycle, which appear increasingly to be inadequate. I argue that, just as one earthquake can trigger others, an imminent paradigm shift in the regulation of the bacterial cell cycle will have repercussions or “paradigm quakes” on hypotheses about the origins of life and about the regulation of the eukaryotic cell cycle. View Full-Text
Keywords: philosophy of science; Kuhn; Fleck; DNA replication; cell division; hyperstructure; phenotypic diversity; heterogeneity; metabolon philosophy of science; Kuhn; Fleck; DNA replication; cell division; hyperstructure; phenotypic diversity; heterogeneity; metabolon
MDPI and ACS Style

Norris, V. Successive Paradigm Shifts in the Bacterial Cell Cycle and Related Subjects. Life 2019, 9, 27.

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