Toward Experimental Evolution with Giant Vesicles
AbstractExperimental evolution in chemical models of cells could reveal the fundamental mechanisms of cells today. Various chemical cell models, water-in-oil emulsions, oil-on-water droplets, and vesicles have been constructed in order to conduct research on experimental evolution. In this review, firstly, recent studies with these candidate models are introduced and discussed with regards to the two hierarchical directions of experimental evolution (chemical evolution and evolution of a molecular self-assembly). Secondly, we suggest giant vesicles (GVs), which have diameters larger than 1 µm, as promising chemical cell models for studying experimental evolution. Thirdly, since technical difficulties still exist in conventional GV experiments, recent developments of microfluidic devices to deal with GVs are reviewed with regards to the realization of open-ended evolution in GVs. Finally, as a future perspective, we link the concept of messy chemistry to the promising, unexplored direction of experimental evolution in GVs. View Full-Text
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Sugiyama, H.; Toyota, T. Toward Experimental Evolution with Giant Vesicles. Life 2018, 8, 53.
Sugiyama H, Toyota T. Toward Experimental Evolution with Giant Vesicles. Life. 2018; 8(4):53.Chicago/Turabian Style
Sugiyama, Hironori; Toyota, Taro. 2018. "Toward Experimental Evolution with Giant Vesicles." Life 8, no. 4: 53.
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