Correction: Al-Qahtani et al. Self-Nanoemulsifying Drug Delivery System of 2-Methoxyestradiol Exhibits Enhanced Anti-Proliferative and Pro-Apoptotic Activities in MCF-7 Breast Cancer Cells. Life 2022, 12, 1369
by
, , , and
Salwa D. Al-Qahtani
1,2, 
Hawazen H. Bin-Melaih
3,
Eman M. Atiya
2,
Usama A. Fahmy
4,
Lenah S. Binmahfouz
5,
Thikryat Neamatallah
5,
Fahad A. Al-Abbasi
2 and
Ashraf B. Abdel-Naim
5,* 1
Department of Medical Laboratory Sciences, Faculty of Applied Medical Science, Majmaah University, Majmaah 11952, Saudi Arabia
2
Department of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah 21589, Saudi Arabia
3
Department of Biological Sciences, Faculty of Sciences, King Abdulaziz University, Jeddah 21589, Saudi Arabia
4
Department of Pharmaceutics, Faculty of Pharmacy, King Abdulaziz University, Jeddah 21589, Saudi Arabia
5
Department of Pharmacology and Toxicology, Faculty of Pharmacy, King Abdulaziz University, Jeddah 21589, Saudi Arabia
*
Author to whom correspondence should be addressed.
Life 2023, 13(6), 1343; https://doi.org/10.3390/life13061343
Submission received: 10 May 2023
/
Accepted: 24 May 2023
/
Published: 8 June 2023
(This article belongs to the Special Issue Pharmaceutical Biotechnology)
Error in Figure
In the original publication [1], there was a mistake in Figure 6A and Figure 7A as published. One sub-image in the replicates of negative control V1 was uploaded instead of V2. The corrected Figure 6 and Figure 7 appear below. The authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated.
Reference
- Al-Qahtani, S.D.; Bin-Melaih, H.H.; Atiya, E.M.; Fahmy, U.A.; Binmahfouz, L.S.; Neamatallah, T.; Al-Abbasi, F.A.; Abdel-Naim, A.B. Self-Nanoemulsifying Drug Delivery System of 2-Methoxyestradiol Exhibits Enhanced Anti-Proliferative and Pro-Apoptotic Activities in MCF-7 Breast Cancer Cells. Life 2022, 12, 1369. [Google Scholar] [CrossRef] [PubMed]
Figure 6.
Flow cytometric analysis of cell cycle distribution of PI-stained MCF-7 cells. (A) Representative flow cytometry histograms after treatment with V1, V2, raw 2ME, 2ME-SNEDDS, and DOX. (B) Cumulative bar chart showing the percentage of cells in the G0/G1, S, and G2/M phases of the cell cycle. (C) Graphic presentation of the percentages of cell cycle phases. Results are presented as mean ± SD (n = 6). * Significantly different from control at p < 0.05, # significantly different from V1 at p < 0.05, $ significantly different from V2 at p < 0.05, † significantly different from raw 2ME at p < 0.05, ‡ significantly different from 2ME-SNEDDS at p < 0.05.
Figure 6.
Flow cytometric analysis of cell cycle distribution of PI-stained MCF-7 cells. (A) Representative flow cytometry histograms after treatment with V1, V2, raw 2ME, 2ME-SNEDDS, and DOX. (B) Cumulative bar chart showing the percentage of cells in the G0/G1, S, and G2/M phases of the cell cycle. (C) Graphic presentation of the percentages of cell cycle phases. Results are presented as mean ± SD (n = 6). * Significantly different from control at p < 0.05, # significantly different from V1 at p < 0.05, $ significantly different from V2 at p < 0.05, † significantly different from raw 2ME at p < 0.05, ‡ significantly different from 2ME-SNEDDS at p < 0.05.
Figure 7.
Flow cytometric analysis of early (lower left quadrant) and late apoptosis (lower right quadrant) and necrosis (upper right quadrant) using annexin V-FITC/PI double staining in MCF-7 cells following challenge with V1, V2, raw 2ME, 2ME-SNEDDS, and DOX. (A) Representative flow cytometric dot plots, (B) graphic presentation of early apoptosis, late apoptosis, necrosis, and total MCF-7 cells death. Results are presented as mean ± SD (n = 6). * Significantly different from control at p < 0.05, # significantly different from V1 at p < 0.05, $ significantly different from V2 at p < 0.05, † significantly different from raw 2ME at p < 0.05, ‡ significantly different from 2ME-SNEDDS at p < 0.05.
Figure 7.
Flow cytometric analysis of early (lower left quadrant) and late apoptosis (lower right quadrant) and necrosis (upper right quadrant) using annexin V-FITC/PI double staining in MCF-7 cells following challenge with V1, V2, raw 2ME, 2ME-SNEDDS, and DOX. (A) Representative flow cytometric dot plots, (B) graphic presentation of early apoptosis, late apoptosis, necrosis, and total MCF-7 cells death. Results are presented as mean ± SD (n = 6). * Significantly different from control at p < 0.05, # significantly different from V1 at p < 0.05, $ significantly different from V2 at p < 0.05, † significantly different from raw 2ME at p < 0.05, ‡ significantly different from 2ME-SNEDDS at p < 0.05.
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MDPI and ACS Style
Al-Qahtani, S.D.; Bin-Melaih, H.H.; Atiya, E.M.; Fahmy, U.A.; Binmahfouz, L.S.; Neamatallah, T.; Al-Abbasi, F.A.; Abdel-Naim, A.B. Correction: Al-Qahtani et al. Self-Nanoemulsifying Drug Delivery System of 2-Methoxyestradiol Exhibits Enhanced Anti-Proliferative and Pro-Apoptotic Activities in MCF-7 Breast Cancer Cells. Life 2022, 12, 1369. Life 2023, 13, 1343. https://doi.org/10.3390/life13061343
AMA Style
Al-Qahtani SD, Bin-Melaih HH, Atiya EM, Fahmy UA, Binmahfouz LS, Neamatallah T, Al-Abbasi FA, Abdel-Naim AB. Correction: Al-Qahtani et al. Self-Nanoemulsifying Drug Delivery System of 2-Methoxyestradiol Exhibits Enhanced Anti-Proliferative and Pro-Apoptotic Activities in MCF-7 Breast Cancer Cells. Life 2022, 12, 1369. Life. 2023; 13(6):1343. https://doi.org/10.3390/life13061343
Chicago/Turabian StyleAl-Qahtani, Salwa D., Hawazen H. Bin-Melaih, Eman M. Atiya, Usama A. Fahmy, Lenah S. Binmahfouz, Thikryat Neamatallah, Fahad A. Al-Abbasi, and Ashraf B. Abdel-Naim. 2023. "Correction: Al-Qahtani et al. Self-Nanoemulsifying Drug Delivery System of 2-Methoxyestradiol Exhibits Enhanced Anti-Proliferative and Pro-Apoptotic Activities in MCF-7 Breast Cancer Cells. Life 2022, 12, 1369" Life 13, no. 6: 1343. https://doi.org/10.3390/life13061343
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