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Peer-Review Record

Low Incidence of Acute Antibody-Mediated Rejection after HLA Desensitization in Living Donor Kidney Transplant Recipients

Life 2022, 12(12), 1993; https://doi.org/10.3390/life12121993
by Constantino Fernández Rivera *, Catuxa Rodríguez Magariños, María Calvo Rodríguez, Tamara Ferreiro Hermida, Marta Blanco Pardo, Andrés López Muñiz, Sara Erráez Guerrero, Leticia García Gago and Ángel Alonso Hernández
Reviewer 1: Anonymous
Reviewer 2:
Life 2022, 12(12), 1993; https://doi.org/10.3390/life12121993
Submission received: 17 October 2022 / Revised: 18 November 2022 / Accepted: 21 November 2022 / Published: 29 November 2022
(This article belongs to the Section Medical Research)

Round 1

Reviewer 1 Report

This is a fine manuscript, but it is disappointing not to have in the first paragraphs a simple, layman's terms, definition of what Desensitization is and what is its purpose (though the authors late define "effective desensitization" which is a related but separate term). So please provide a simple straightforward definition for Desensitization. Similarly in the introduction define, in very simple terms, what is meant by acute rejection. Any non-specialized reader sent to Google search these terms is a reader lost unnecessarily. Everything else looks fine

Minor point: in line 53 "...Hospital, Spain, has performed..." - delete the "has"

Author Response

Please see the attachment.

Author Response File: Author Response.docx

Reviewer 2 Report

Suggestions:

1. to change "HLA incompatible transplants." to crossmatch positive transplants. 

2. Figure 3 can be removed

3. Figure 4 can be removed

4. Table 6 can be removed

5. Typographical errors line 44, 135, 290, 323, 326

6. Sentence construction line 274

Author Response

Please see the attachment.

Author Response File: Author Response.docx

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