Fine-Needle Aspiration Cytology for Parotid Tumors
Abstract
:1. Introduction
2. History of Fine Needle Aspiration
3. Features of Parotid Gland Cytology
4. Specimen Collection and Processing Procedures
4.1. Fine Needle Aspiration Cytology
4.2. Core Needle Biopsy
4.3. Liquid-Based Cytology
5. Ancillary Diagnosis in Salivary Gland Cytology
6. Frozen Section Biopsy
7. Classification Systems
7.1. Milan System
7.1.1. I. Non-diagnostic (ROM 25%)
7.1.2. II. Non-neoplastic (ROM 10%)
7.1.3. III. AUS (ROM 20%)
7.1.4. IV. Neoplasm
IVA. Neoplasm—Benign (ROM ≤ 5%)
IVB. Neoplasm—SUMP (ROM 35%)
7.1.5. V. Suspicious for Malignancy (ROM 60%)
7.1.6. VI. Malignant (ROM 90%)
7.2. Osaka Medical College Classification
8. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Procedure | Advantages | Disadvantages |
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Fine needle aspiration |
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Core needle biopsy |
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Liquid-based cytology |
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Milan System | Osaka Medical College Classification | |
---|---|---|
I. Non-diagnostic | 1-1 Inadequate | |
1-2 Cyst contents | ||
II. Non-neoplastic | 2 Non-neoplastic | |
III. AUS | 3 AUS | |
IV. Neoplasm | 4-1 Benign tumor (histology confirmed) | |
IVA. Neoplasm—benign | 4-2 Benign tumor (histology unconfirmed) | |
IVB. Neoplasm—SUMP | 5 SUMP | |
V. Suspicious for malignancy | 6-1 Suspicious for malignancy | |
VI. Malignant | 6-2 Malignant (grade/histology unconfirmed) | |
6-3 Malignant (grade confirmed) | ||
6-4 Malignant (grade/histology confirmed) |
1-1 | 1-2 | 2 | 3 | 4-1 | 4-2 | 5 | 6-1 | 6-2 | 6-3 | 6-4 | |
---|---|---|---|---|---|---|---|---|---|---|---|
Malignant (n = 194) (113/81) | 26 (18/8) | 2 (2/0) | 5 (4/1) | 0 | 12 (9/3) | 13 (13/0) | 23 (15/8) | 13 (10/3) | 18 (7/11) | 21 (6/15) | 61 (29/3) |
Benign (n = 981) | 133 | 20 | 27 | 8 | 717 | 38 | 26 | 4 | 3 | 1 | 4 |
Total (%) | 13.5 | 1.9 | 2.7 | 0.7 | 62.0 | 4.3 | 4.2 | 1.4 | 1.8 | 1.9 | 5.5 |
ROM (%) | 16.4 | 9.1 | 15.6 | 0.0 | 1.6 | 25.5 | 46.9 | 76.5 | 85.7 | 95.5 | 93.8 |
1-1 | 1-2 | 2 | 3 | 4-1 | 4-2 | 5 | 6-1 | 6-2 | 6-3 | 6-4 | Total | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Malignant | ||||||||||||
MEC | 8 (6/2) | 1 (1/0) | 3 (2/1) | 0 | 2 (1/1) | 3 (3/0) | 7 (4/3) | 4 (3/1) | 3 (1/2) | 3 (1/2) | 17 (4/13) | 51 |
Ca ex pleo | 2 (1/1) | 4 (2/2) | 3 (3/0) | 3 (0/3) | 1 (0/1) | 6 (2/4) | 4 (1/3) | 6 (2/4) | 29 | |||
AdCC | 3 (2/1) | 1 (1/0) | 2 (2/0) | 3 (3/0) | 1 (1/0) | 3 (0/3) | 9 (8/1) | 22 | ||||
SDC | 1 | 1 | 1 | 8 | 7 | 18 | ||||||
Benign | ||||||||||||
Pleo | 40 | 3 | 7 | 3 | 515 | 16 | 12 | 2 | 3 | 1 | 3 | 605 |
Warthin | 39 | 2 | 10 | 3 | 166 | 6 | 3 | 1 | 225 | |||
BCA | 11 | 21 | 11 | 3 | 1 | 47 |
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Taniuchi, M.; Terada, T.; Kawata, R. Fine-Needle Aspiration Cytology for Parotid Tumors. Life 2022, 12, 1897. https://doi.org/10.3390/life12111897
Taniuchi M, Terada T, Kawata R. Fine-Needle Aspiration Cytology for Parotid Tumors. Life. 2022; 12(11):1897. https://doi.org/10.3390/life12111897
Chicago/Turabian StyleTaniuchi, Masataka, Tetsuya Terada, and Ryo Kawata. 2022. "Fine-Needle Aspiration Cytology for Parotid Tumors" Life 12, no. 11: 1897. https://doi.org/10.3390/life12111897