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State-of-the-Art: Inflammatory and Metabolic Markers in Mood Disorders

1
Dipartimento di Medicina Clinica e Sperimentale, Section of Psychiatry, University of Pisa, 56100 Pisa, Italy
2
Dipartimento di Biotecnologie, Chimica e Farmacia, University of Siena, 53100 Siena, Italy
3
Casa di Cura Morana, 91025 Marsala, Italy
*
Author to whom correspondence should be addressed.
Life 2020, 10(6), 82; https://doi.org/10.3390/life10060082
Received: 28 March 2020 / Revised: 10 May 2020 / Accepted: 15 May 2020 / Published: 6 June 2020
(This article belongs to the Section Medical Research)
Mounting evidence highlights the involvement of inflammatory/immune systems and their relationships with neurotransmitters and different metabolic processes in mood disorders. Nevertheless, there is a general agreement that available findings are still inconclusive. Therefore, further investigations are required, aimed at deepening the role of possible alterations of biomarkers in the pathophysiology of mood disorders that might lead to more focused and tailored treatments. The present study is a comprehensive review on these topics that seem to represent intriguing avenues for the development of real innovative therapeutic strategies of mood disorders. View Full-Text
Keywords: mood disorders; neurotransmitters/neuroreceptors; serotonin; immune system; neuro-inflammation; hypothalamus-pituitary-adrenal axis; neurotrophins; uric acid; oxidative stress mood disorders; neurotransmitters/neuroreceptors; serotonin; immune system; neuro-inflammation; hypothalamus-pituitary-adrenal axis; neurotrophins; uric acid; oxidative stress
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Mucci, F.; Marazziti, D.; Della Vecchia, A.; Baroni, S.; Morana, P.; Carpita, B.; Mangiapane, P.; Morana, F.; Morana, B.; Dell’Osso, L. State-of-the-Art: Inflammatory and Metabolic Markers in Mood Disorders. Life 2020, 10, 82.

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