Loss of natural soil and vegetation within the urban environment can significantly affect the hydrologic cycle by increasing storm water runoff rates and volumes. In order to mitigate these modifications in urban areas engineered systems are developed, such as green roofs, to mimic and replace functions (evapo-transpiration, infiltration, percolation) which have been altered due to the impact of human development. Green roofs, also known as vegetated roof covers, eco-roofs or nature roofs, are composite complex layered structures with specific environmental benefits. They are increasingly being used as a source control measure for urban storm water management. Indeed, they are able to re-establish the natural water cycle processes and to operate hydrologic control over storm water runoff with a derived peak flow attenuation, runoff volume reduction and increase of the time of concentration. Furthermore green roofs exhibit the capacity to reduce storm water pollution; they generally act as a storage device, consequently pollutants are accumulated in the substrate layer and released when intensive rainwater washes them out. In order to investigate the hydrologic response of a green roof, the University of Genova recently developed a joint laboratory and full-scale monitoring programme by installing a “controlled” laboratory test-bed with known rainfall input and a companion green roof experimental site (40 cm depth) in the town of Genoa. In the paper, data collected during the monitoring programme are presented and compared with literature data.