Versatility of Synthetic tRNAs in Genetic Code Expansion
Abstract
1. Introduction
2. Aspects of Heterologous tRNA Expression
2.1. Identity Elements and Recognition
2.2. Heterologous tRNA Modification and Maturation
3. When Amino Acid Biosynthesis is o-tRNA-Dependent: Challenges in tRNASec Engineering
3.1. tRNASec Interactions
3.2. Converting tRNASec Recognition from SelB to EF-Tu
3.3. Improving Ser-to-Sec Conversion
3.4. Different tRNASec Structures for the Optimization of Selenoprotein Production
4. Absolutely Orthogonal? Unique Features of tRNAPyl
5. Conclusions/Outlook
Author Contributions
Funding
Acknowledgments
Conflicts of Interest
References
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Hoffman, K.S.; Crnković, A.; Söll, D. Versatility of Synthetic tRNAs in Genetic Code Expansion. Genes 2018, 9, 537. https://doi.org/10.3390/genes9110537
Hoffman KS, Crnković A, Söll D. Versatility of Synthetic tRNAs in Genetic Code Expansion. Genes. 2018; 9(11):537. https://doi.org/10.3390/genes9110537
Chicago/Turabian StyleHoffman, Kyle S., Ana Crnković, and Dieter Söll. 2018. "Versatility of Synthetic tRNAs in Genetic Code Expansion" Genes 9, no. 11: 537. https://doi.org/10.3390/genes9110537
APA StyleHoffman, K. S., Crnković, A., & Söll, D. (2018). Versatility of Synthetic tRNAs in Genetic Code Expansion. Genes, 9(11), 537. https://doi.org/10.3390/genes9110537