Next Article in Journal
BARHL1 Is Downregulated in Alzheimer’s Disease and May Regulate Cognitive Functions through ESR1 and Multiple Pathways
Next Article in Special Issue
Organ-on-Chip Technology: Current State and Future Developments
Previous Article in Journal
Genetic Association between Amyotrophic Lateral Sclerosis and Cancer
Previous Article in Special Issue
High-Throughput Study of the Effects of Celastrol on Activated Fibroblast-Like Synoviocytes from Patients with Rheumatoid Arthritis
Article Menu
Issue 10 (October) cover image

Export Article

Open AccessReview

Air Quality Effects on Human Health and Approaches for Its Assessment through Microfluidic Chips

German Federal Institute for Risk Assessment (BfR), German Centre for the Protection of Laboratory Animals (Bf3R), 10589 Berlin, Germany
iSmart, Materials Genome Institute, Shanghai University (SHU), Shanghai 201800, China
Department of Electrical Engineering, Kaunas University of Technology, 35212 Panevezys, Lithuania
Department of Biochemistry, King Abdulaziz University, Jeddah 80203, Saudi Arabia
Institute for Synthetic Bioarchitecture, Department of Nanobiotechnology, University of Natural Resources and Life Sciences, 1190 Vienna, Austria
Mathematics and Natural Sciences Department, The American University of Iraq, Sulaimani, Sulaymaniyah 46001, Iraq
Authors to whom correspondence should be addressed.
Genes 2017, 8(10), 244;
Received: 2 August 2017 / Revised: 11 September 2017 / Accepted: 20 September 2017 / Published: 27 September 2017
(This article belongs to the Special Issue From the Lab-on-a-Chip to the Organ-on-a-Chip)
PDF [2026 KB, uploaded 27 September 2017]


Air quality depends on the various gases and particles present in it. Both natural phenomena and human activities affect the cleanliness of air. In the last decade, many countries experienced an unprecedented industrial growth, resulting in changing air quality values, and correspondingly, affecting our life quality. Air quality can be accessed by employing microchips that qualitatively and quantitatively determine the present gases and dust particles. The so-called particular matter 2.5 (PM2.5) values are of high importance, as such small particles can penetrate the human lung barrier and enter the blood system. There are cancer cases related to many air pollutants, and especially to PM2.5, contributing to exploding costs within the healthcare system. We focus on various current and potential future air pollutants, and propose solutions on how to protect our health against such dangerous substances. Recent developments in the Organ-on-Chip (OoC) technology can be used to study air pollution as well. OoC allows determination of pollutant toxicity and speeds up the development of novel pharmaceutical drugs. View Full-Text
Keywords: air pollution; particulate matter (PM); PM2.5; microchip; organ-on-chip (OoC) air pollution; particulate matter (PM); PM2.5; microchip; organ-on-chip (OoC)

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

Share & Cite This Article

MDPI and ACS Style

Schulze, F.; Gao, X.; Virzonis, D.; Damiati, S.; Schneider, M.R.; Kodzius, R. Air Quality Effects on Human Health and Approaches for Its Assessment through Microfluidic Chips. Genes 2017, 8, 244.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics



[Return to top]
Genes EISSN 2073-4425 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top