The Two-Faced Role of crAssphage Subfamilies in Obesity and Metabolic Syndrome: Between Good and Evil
Abstract
:1. Introduction
2. Materials and Methods
2.1. Acquisition of Viral Data and Mapping to the crAssphage Genome Database
2.2. crAssphages α- and β-Diversities
2.3. Association of crAssphage Abundance with Metadata Variables and Microbiota
2.4. Correlation of crAssphage Abundance with Their Bacterial Host
3. Results
3.1. Decreased Abundance and Prevalence of crAssphages Were Detected in the O and OMS Groups
3.2. Changes in crAssphage Taxonomy Characterize the O and OMS Groups
3.3. Decreased Diversity and Richness of α crAssphages Are Associated with the O and OMS Groups
3.4. Host Bacteria of crAssphages Were Decreased in the O and OMS Groups
3.5. Increased Bacilli Were Associated with Decreased crAssphage Abundance in OMS
4. Discussion
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Cervantes-Echeverría, M.; Gallardo-Becerra, L.; Cornejo-Granados, F.; Ochoa-Leyva, A. The Two-Faced Role of crAssphage Subfamilies in Obesity and Metabolic Syndrome: Between Good and Evil. Genes 2023, 14, 139. https://doi.org/10.3390/genes14010139
Cervantes-Echeverría M, Gallardo-Becerra L, Cornejo-Granados F, Ochoa-Leyva A. The Two-Faced Role of crAssphage Subfamilies in Obesity and Metabolic Syndrome: Between Good and Evil. Genes. 2023; 14(1):139. https://doi.org/10.3390/genes14010139
Chicago/Turabian StyleCervantes-Echeverría, Melany, Luigui Gallardo-Becerra, Fernanda Cornejo-Granados, and Adrian Ochoa-Leyva. 2023. "The Two-Faced Role of crAssphage Subfamilies in Obesity and Metabolic Syndrome: Between Good and Evil" Genes 14, no. 1: 139. https://doi.org/10.3390/genes14010139
APA StyleCervantes-Echeverría, M., Gallardo-Becerra, L., Cornejo-Granados, F., & Ochoa-Leyva, A. (2023). The Two-Faced Role of crAssphage Subfamilies in Obesity and Metabolic Syndrome: Between Good and Evil. Genes, 14(1), 139. https://doi.org/10.3390/genes14010139