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Article
Peer-Review Record

Different Strategies for the Identification of SARS-CoV-2 Variants in the Laboratory Practice

Genes 2021, 12(9), 1428; https://doi.org/10.3390/genes12091428
by Federico Anaclerio 1,†, Rossella Ferrante 1,†, Domitilla Mandatori 1,2,*, Ivana Antonucci 1,3, Matteo Capanna 1, Verena Damiani 1,4, Pamela Di Tomo 1,2, Roberto Ferrante 1, Marianna Ranaudo 1, Vincenzo De Laurenzi 1,4, Liborio Stuppia 1,3 and Simone De Fabritiis 1,5
Reviewer 1: Anonymous
Reviewer 2: Anonymous
Genes 2021, 12(9), 1428; https://doi.org/10.3390/genes12091428
Submission received: 19 August 2021 / Accepted: 14 September 2021 / Published: 16 September 2021
(This article belongs to the Special Issue COVID-19 and Molecular Genetics)

Round 1

Reviewer 1 Report

The object of the study is relevant to date.

The paper as a significant content with a good quality of data presentation.

Great interests for reader.

The main question addressed SARS-CoV-2 VARIANTS IN LABORATORY PRACTICE by the research.  It is relevant and interesting. In addition,  it added TECHNOLOGICAL AND METHODOLOGICAL SUGGESTIONS, RESULTS OF A WIDE STUDY to the subject area compared with other published material. The text is clear and easy to read.

Reviewer 2 Report

In this paper, the authors report the experience as one of the Italian laboratories involved in SARS-CoV-2 variants tracing. We summarize the different approaches used and outline a potential model combining several techniques to increase tracing ability and at the same time minimize costs.

Moreover, this approach allows rapid tracing of known variants and the possibility of alerting local authorities of their spreading almost in real-time, thus providing better control of the pandemic.

the work is clear and well structured and the conclusions to which it comes are shareable

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