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Store-Independent Calcium Entry and Related Signaling Pathways in Breast Cancer

Laboratory of Cellular and Molecular Physiology, UR-UPJV 4667, University of Picardie Jules Verne, 80000 Amiens, France
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Academic Editors: Iman Azimi and Irmgard Irminger-Finger
Genes 2021, 12(7), 994; https://doi.org/10.3390/genes12070994
Received: 20 April 2021 / Revised: 12 June 2021 / Accepted: 25 June 2021 / Published: 29 June 2021
(This article belongs to the Special Issue Calcium Signalling in Cancer)
Known as a key effector in breast cancer (BC) progression, calcium (Ca2+) is tightly regulated to maintain the desired concentration to fine-tune cell functions. Ca2+ channels are the main actors among Ca2+ transporters that control the intracellular Ca2+ concentration in cells. It is well known that the basal Ca2+ concentration is regulated by both store-dependent and independent Ca2+ channels in BC development and progression. However, most of the literature has reported the role of store-dependent Ca2+ entry, and only a few studies are focusing on store-independent Ca2+ entry (SICE). In this review, we aim to summarize all findings on SICE in the BC progression field. View Full-Text
Keywords: calcium channels; basal calcium entry; Orai-K+ channel complex; transient receptor potential channels; voltage-gated calcium channels; breast cancer calcium channels; basal calcium entry; Orai-K+ channel complex; transient receptor potential channels; voltage-gated calcium channels; breast cancer
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MDPI and ACS Style

Chamlali, M.; Rodat-Despoix, L.; Ouadid-Ahidouch, H. Store-Independent Calcium Entry and Related Signaling Pathways in Breast Cancer. Genes 2021, 12, 994. https://doi.org/10.3390/genes12070994

AMA Style

Chamlali M, Rodat-Despoix L, Ouadid-Ahidouch H. Store-Independent Calcium Entry and Related Signaling Pathways in Breast Cancer. Genes. 2021; 12(7):994. https://doi.org/10.3390/genes12070994

Chicago/Turabian Style

Chamlali, Mohamed, Lise Rodat-Despoix, and Halima Ouadid-Ahidouch. 2021. "Store-Independent Calcium Entry and Related Signaling Pathways in Breast Cancer" Genes 12, no. 7: 994. https://doi.org/10.3390/genes12070994

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