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Cannabinoid Control of Olfactory Processes: The Where Matters

INSERM, U1215 NeuroCentre Magendie, 146 rue Léo Saignat, CEDEX, 33077 Bordeaux, France
University of Bordeaux, 146 rue Léo Saignat, 33000 Bordeaux, France
Interdisciplinary Institute for Neuroscience, CNRS, UMR 5297, 33000 Bordeaux, France
Department of Neurosciences, University of the Basque Country UPV/EHU, Barrio Sarriena s\n, 48940 Leioa, Spain
Achucarro Basque Center for Neuroscience, Science Park of the UPV/EHU, 48940 Leioa, Spain
IKERBASQUE, Basque Foundation for Science, Maria Diaz de Haro 3, 48013 Bilbao, Spain
Author to whom correspondence should be addressed.
Genes 2020, 11(4), 431;
Received: 25 February 2020 / Revised: 7 April 2020 / Accepted: 13 April 2020 / Published: 16 April 2020
(This article belongs to the Special Issue Olfaction: From Genes to Behavior)
Olfaction has a direct influence on behavior and cognitive processes. There are different neuromodulatory systems in olfactory circuits that control the sensory information flowing through the rest of the brain. The presence of the cannabinoid type-1 (CB1) receptor, (the main cannabinoid receptor in the brain), has been shown for more than 20 years in different brain olfactory areas. However, only over the last decade have we started to know the specific cellular mechanisms that link cannabinoid signaling to olfactory processing and the control of behavior. In this review, we aim to summarize and discuss our current knowledge about the presence of CB1 receptors, and the function of the endocannabinoid system in the regulation of different olfactory brain circuits and related behaviors. View Full-Text
Keywords: olfaction; endocannabinoids; olfactory epithelium; olfactory bulb; piriform cortex; CB1 receptor olfaction; endocannabinoids; olfactory epithelium; olfactory bulb; piriform cortex; CB1 receptor
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MDPI and ACS Style

Terral, G.; Marsicano, G.; Grandes, P.; Soria-Gómez, E. Cannabinoid Control of Olfactory Processes: The Where Matters. Genes 2020, 11, 431.

AMA Style

Terral G, Marsicano G, Grandes P, Soria-Gómez E. Cannabinoid Control of Olfactory Processes: The Where Matters. Genes. 2020; 11(4):431.

Chicago/Turabian Style

Terral, Geoffrey, Giovanni Marsicano, Pedro Grandes, and Edgar Soria-Gómez. 2020. "Cannabinoid Control of Olfactory Processes: The Where Matters" Genes 11, no. 4: 431.

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