Next Article in Journal
Atg8-Family Proteins—Structural Features and Molecular Interactions in Autophagy and Beyond
Previous Article in Journal
Tributyrin Attenuates Metabolic and Inflammatory Changes Associated with Obesity through a GPR109A-Dependent Mechanism
Previous Article in Special Issue
Non-Muscle Myosin II in Axonal Cell Biology: From the Growth Cone to the Axon Initial Segment
Open AccessReview

Actomyosin Contractility in the Generation and Plasticity of Axons and Dendritic Spines

1
RG Optobiology, Institute of Biology, Humboldt Universität zu Berlin, 10115 Berlin, Germany
2
DFG Emmy Noether Group ‘Neuronal Protein Transport’, Center for Molecular Neurobiology, ZMNH, University Medical Center Hamburg-Eppendorf, 20251 Hamburg, Germany
3
Institut für Chemie und Biochemie, Freie Universität Berlin, 14195 Berlin, Germany
*
Authors to whom correspondence should be addressed.
Cells 2020, 9(9), 2006; https://doi.org/10.3390/cells9092006
Received: 17 July 2020 / Revised: 19 August 2020 / Accepted: 25 August 2020 / Published: 1 September 2020
(This article belongs to the Special Issue Actin-Myosin Cytoskeleton Regulation and Function)
Actin and non-muscle myosins have long been known to play important roles in growth cone steering and neurite outgrowth. More recently, novel functions for non-muscle myosin have been described in axons and dendritic spines. Consequently, possible roles of actomyosin contraction in organizing and maintaining structural properties of dendritic spines, the size and location of axon initial segment and axonal diameter are emerging research topics. In this review, we aim to summarize recent findings involving myosin localization and function in these compartments and to discuss possible roles for actomyosin in their function and the signaling pathways that control them. View Full-Text
Keywords: actin; myosin; spectrin; calpain; calcium signaling; AIS; dendritic spines actin; myosin; spectrin; calpain; calcium signaling; AIS; dendritic spines
Show Figures

Figure 1

MDPI and ACS Style

Mikhaylova, M.; Rentsch, J.; Ewers, H. Actomyosin Contractility in the Generation and Plasticity of Axons and Dendritic Spines. Cells 2020, 9, 2006.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Search more from Scilit
 
Search
Back to TopTop