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Polymers 2015, 7(9), 1837-1849;

Biocatalytic Self-Cleaning Polymer Membranes

Leibniz Institute of Surface Modification, Permoserstr. 15, Leipzig D-04318, Germany
Author to whom correspondence should be addressed.
Academic Editor: Scott M. Husson
Received: 25 June 2015 / Revised: 26 August 2015 / Accepted: 15 September 2015 / Published: 21 September 2015
(This article belongs to the Special Issue Polymer Thin Films and Membranes 2015)
PDF [1732 KB, uploaded 21 September 2015]


Polymer membrane surfaces have been equipped with the digestive enzyme trypsin. Enzyme immobilization was performed by electron beam irradiation in aqueous media within a one-step method. Using this method, trypsin was covalently and side-unspecific attached to the membrane surface. Thus, the use of preceding polymer functionalization and the use of toxic solvents or reagents can be avoided. The resulting membranes showed significantly improved antifouling properties as demonstrated by repeated filtration of protein solutions. Furthermore, the biocatalytic membrane can be simply “switched on” to actively degrade a fouling layer on the membrane surface and regain the initial permeability. The membrane pore structure (pore size and porosity) was neither damaged by the electron beam treatment nor blocked by the enzyme loading, ensuring a stable membrane performance. View Full-Text
Keywords: surface modification; enzyme immobilization; fouling reduction; self-cleaning surface modification; enzyme immobilization; fouling reduction; self-cleaning

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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MDPI and ACS Style

Schulze, A.; Stoelzer, A.; Striegler, K.; Starke, S.; Prager, A. Biocatalytic Self-Cleaning Polymer Membranes. Polymers 2015, 7, 1837-1849.

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