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Polymers 2011, 3(3), 1255-1267;

Spontaneous Vesicles Modulated by Polymers

Departamento de Química Física, Universidad de Salamanca, E-37008 Salamanca, Spain
Departamento de Química Física I, Facultad de Ciencias Químicas, Universidad Complutense de Madrid, E-28040 Madrid, Spain
Author to whom correspondence should be addressed.
Received: 7 June 2011 / Revised: 19 July 2011 / Accepted: 4 August 2011 / Published: 8 August 2011
(This article belongs to the Special Issue Water-Soluble Polymers)
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Vesicles are widely used in technological applications including cosmetic products, in microencapsulation for drug delivery, as anticancer agents and in the technology of adhesives, paints and inks. The vesicle size and the surface charge are very important properties from a technological point of view. Thus, the challenge in formulation is to find inexpensive stable vesicles with well-defined sizes and to modulate the surface charge of these aggregates. In this work we analyze the effect of different polymers on the structural properties of vesicles of the biodegradable surfactant sodium bis(2-ethyl-hexyl) sulfosuccinate, Aerosol OT. Using fluorescence, conductivity, electrophoretic mobility and dynamic light scattering measurements we study the effect of the polymer nature, molecular weight and polymer concentration on the stability and the vesicle size properties. Results demonstrate that it is possible to modulate both the size and the electric surface charge of spontaneous vesicles of Aerosol OT by the addition of very small percentages of poly(allylamine) and poly(maleic anhydride-alt-1-octadecen). View Full-Text
Keywords: Aerosol OT; light scattering measurements; ζ-potential; electrical conductivity; poly(maleic anhydride-alt-1-octadecen); poly(allylamine) Aerosol OT; light scattering measurements; ζ-potential; electrical conductivity; poly(maleic anhydride-alt-1-octadecen); poly(allylamine)
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Velázquez, M.M.; Valero, M.; Ortega, F. Spontaneous Vesicles Modulated by Polymers. Polymers 2011, 3, 1255-1267.

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