Next Article in Journal
Shelf Life of Fresh Sliced Sea Bream Pack in PET Nanocomposite Trays
Previous Article in Journal
Tuning the Adhesive Properties of Soy Protein Wood Adhesives with Different Coadjutant Polymers, Nanocellulose and Lignin
Previous Article in Special Issue
Electrospun Functional Nanofiber Membrane for Antibiotic Removal in Water: Review
Review

Non-Toxic Crosslinking of Electrospun Gelatin Nanofibers for Tissue Engineering and Biomedicine—A Review

Working Group Textile Technologies, Faculty of Engineering and Mathematics, Bielefeld University of Applied Sciences, 33619 Bielefeld, Germany
Academic Editor: Cesare Cametti
Polymers 2021, 13(12), 1973; https://doi.org/10.3390/polym13121973
Received: 31 May 2021 / Revised: 12 June 2021 / Accepted: 13 June 2021 / Published: 15 June 2021
(This article belongs to the Special Issue Electrospun Biomaterials)
Electrospinning can be used to prepare nanofiber mats from diverse polymers, polymer blends, or polymers doped with other materials. Amongst this broad range of usable materials, biopolymers play an important role in biotechnological, biomedical, and other applications. However, several of them are water-soluble, necessitating a crosslinking step after electrospinning. While crosslinking with glutaraldehyde or other toxic chemicals is regularly reported in the literature, here, we concentrate on methods applying non-toxic or low-toxic chemicals, and enzymatic as well as physical methods. Making gelatin nanofibers non-water soluble by electrospinning them from a blend with non-water soluble polymers is another method described here. These possibilities are described together with the resulting physical properties, such as swelling behavior, mechanical strength, nanofiber morphology, or cell growth and proliferation on the crosslinked nanofiber mats. For most of these non-toxic crosslinking methods, the degree of crosslinking was found to be lower than for crosslinking with glutaraldehyde and other common toxic chemicals. View Full-Text
Keywords: nanofiber blends; water-solubility; polymer complex; polymer blend; crosslinker; genipin; aldehydes; UV-crosslinking; electron beam; photo initiator nanofiber blends; water-solubility; polymer complex; polymer blend; crosslinker; genipin; aldehydes; UV-crosslinking; electron beam; photo initiator
Show Figures

Figure 1

MDPI and ACS Style

Ehrmann, A. Non-Toxic Crosslinking of Electrospun Gelatin Nanofibers for Tissue Engineering and Biomedicine—A Review. Polymers 2021, 13, 1973. https://doi.org/10.3390/polym13121973

AMA Style

Ehrmann A. Non-Toxic Crosslinking of Electrospun Gelatin Nanofibers for Tissue Engineering and Biomedicine—A Review. Polymers. 2021; 13(12):1973. https://doi.org/10.3390/polym13121973

Chicago/Turabian Style

Ehrmann, Andrea. 2021. "Non-Toxic Crosslinking of Electrospun Gelatin Nanofibers for Tissue Engineering and Biomedicine—A Review" Polymers 13, no. 12: 1973. https://doi.org/10.3390/polym13121973

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop