3D Printing and Bioprinting Nerve Conduits for Neural Tissue Engineering
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School of Chemistry, Chemical Engineering and Life Science, Wuhan University of Technology, Wuhan 430070, China
2
State Key Laboratory of Silicate Materials for Architectures, Wuhan University of Technology, Wuhan 430070, China
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Authors to whom correspondence should be addressed.
Polymers 2020, 12(8), 1637; https://doi.org/10.3390/polym12081637
Received: 2 July 2020
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Revised: 17 July 2020
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Accepted: 21 July 2020
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Published: 23 July 2020
(This article belongs to the Special Issue 3D Printing Polyesters, Hydrogels and Composites for Medical Applications)
Fabrication of nerve conduits for perfectly repairing or replacing damaged peripheral nerve is an urgent demand worldwide, but it is also a formidable clinical challenge. In the last decade, with the rapid development of manufacture technologies, 3D printing and bioprinting have been becoming remarkable stars in the field of neural engineering. In this review, we explore that the biomaterial inks (hydrogels, thermoplastic, and thermoset polyesters and composite) and bioinks have been selected for 3D printing and bioprinting of peripheral nerve conduits. This review covers 3D manufacturing technologies, including extrusion printing, inkjet printing, stereolithography, and bioprinting with inclusion of cells, bioactive molecules, and drugs. Finally, an outlook on the future directions of 3D printing and 4D printing in customizable nerve therapies is presented.
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Keywords:
3D printing; bioprinting; hydrogel; polyester; peripheral nerve regeneration
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited
MDPI and ACS Style
Yu, X.; Zhang, T.; Li, Y. 3D Printing and Bioprinting Nerve Conduits for Neural Tissue Engineering. Polymers 2020, 12, 1637. https://doi.org/10.3390/polym12081637
AMA Style
Yu X, Zhang T, Li Y. 3D Printing and Bioprinting Nerve Conduits for Neural Tissue Engineering. Polymers. 2020; 12(8):1637. https://doi.org/10.3390/polym12081637
Chicago/Turabian StyleYu, Xiaoling, Tian Zhang, and Yuan Li. 2020. "3D Printing and Bioprinting Nerve Conduits for Neural Tissue Engineering" Polymers 12, no. 8: 1637. https://doi.org/10.3390/polym12081637
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