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Open AccessArticle

The Ophthalmic Performance of Hydrogel Contact Lenses Loaded with Silicone Nanoparticles

Department of Materials Science and Engineering, National Taiwan University of Science and Technology, Taipei 10607, Taiwan
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Author to whom correspondence should be addressed.
Polymers 2020, 12(5), 1128; https://doi.org/10.3390/polym12051128
Received: 13 April 2020 / Revised: 6 May 2020 / Accepted: 11 May 2020 / Published: 14 May 2020
(This article belongs to the Special Issue Advanced Polymer Nanocomposites)
In this study, silicone nanoparticles (SiNPs) were prepared from polydimethylsiloxane (PDMS) and tetraethyl orthosilicate (TEOS) via the sol-gel process. The resultant SiNPs were characterized by dynamic light scattering (DLS), transmission electron microscope (TEM), and scanning electron microscope (SEM). These SiNPs were then blended with 2-hydroxyethylmethacrylate (HEMA) and 1-vinyl-2-pyrrolidinone (NVP) before polymerizing into hydrogel contact lenses. All hydrogels were subject to characterization, including equilibrium water content (EWC), contact angle, and oxygen permeability (Dk). The average diameter of SiNPs was 330 nm. The results indicated that, with the increase of SiNPs content, the oxygen permeability increased, while the EWC was affected insignificantly. The maximum oxygen permeability attained was 71 barrer for HEMA-NVP lens containing 1.2 wt% of SiNPs with an EWC of 73%. These results demonstrate that by loading a small amount of SiNPs, the Dk of conventional hydrogel lenses can be improved greatly. This approach would be a new method to produce oxygen-permeable contact lenses. View Full-Text
Keywords: silicone nanoparticles; PDMS; TEOS; hydrogels; soft contact lenses silicone nanoparticles; PDMS; TEOS; hydrogels; soft contact lenses
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MDPI and ACS Style

Tran, N.-P.-D.; Yang, M.-C. The Ophthalmic Performance of Hydrogel Contact Lenses Loaded with Silicone Nanoparticles. Polymers 2020, 12, 1128.

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