Well Defined Poly(Methyl Methacrylate)-Fe3O4/Poly(Vinyl Pivalate) Core–Shell Superparamagnetic Nanoparticles: Design and Evaluation of In Vitro Cytotoxicity Activity Against Cancer Cells
Abstract
:1. Introduction
2. Materials and Methods
2.1. Synthesis of Magnetic Nanoparticles (OM)
2.2. Coating of Magnetic Nanoparticles with Oleic Acid (OM-OA)
2.3. Synthesis of PMMA/OM-OA Magnetic Nanocomposite
2.4. Production of Poly(Vinyl Pivalate) Shell via Seeded Emulsion Polymerization
2.5. Sample Characterization
2.6. In Vitro Cytotoxicity Assays
3. Results and Discussion
4. Conclusions
Author Contributions
Funding
Acknowledgments
Conflicts of Interest
References
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Wavenumbers (cm−1) | Vibrational Assignments |
---|---|
2995–2852 | Asymmetrical and symmetrical stretch C-H sp3 |
1731 | Stretch C=O of ester |
1489 and 1446 | Angular deformation of methylene groups (–CH2) |
1381 and 1365 | Symmetrical angular deformation –CH3 of tert-butyl groups |
1272 and 1149 | Stretch C-O of ester |
985 | Out of plane angular deformation C-H |
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Resende, G.; Dutra, G.V.S.; Neta, M.S.B.; Araújo, O.A.; Chaves, S.B.; Machado, F. Well Defined Poly(Methyl Methacrylate)-Fe3O4/Poly(Vinyl Pivalate) Core–Shell Superparamagnetic Nanoparticles: Design and Evaluation of In Vitro Cytotoxicity Activity Against Cancer Cells. Polymers 2020, 12, 2868. https://doi.org/10.3390/polym12122868
Resende G, Dutra GVS, Neta MSB, Araújo OA, Chaves SB, Machado F. Well Defined Poly(Methyl Methacrylate)-Fe3O4/Poly(Vinyl Pivalate) Core–Shell Superparamagnetic Nanoparticles: Design and Evaluation of In Vitro Cytotoxicity Activity Against Cancer Cells. Polymers. 2020; 12(12):2868. https://doi.org/10.3390/polym12122868
Chicago/Turabian StyleResende, Graciane, Gabriel V. S. Dutra, Maria S. B. Neta, Olacir A. Araújo, Sacha B. Chaves, and Fabricio Machado. 2020. "Well Defined Poly(Methyl Methacrylate)-Fe3O4/Poly(Vinyl Pivalate) Core–Shell Superparamagnetic Nanoparticles: Design and Evaluation of In Vitro Cytotoxicity Activity Against Cancer Cells" Polymers 12, no. 12: 2868. https://doi.org/10.3390/polym12122868