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3D Bioprinted Nanocellulose-Based Hydrogels for Tissue Engineering Applications: A Brief Review

Chemical and Environmental Engineering, School of Engineering, RMIT University, Melbourne, Victoria 3000, Australia
Authors to whom correspondence should be addressed.
Polymers 2019, 11(5), 898;
Received: 29 March 2019 / Revised: 25 April 2019 / Accepted: 26 April 2019 / Published: 17 May 2019
PDF [3375 KB, uploaded 17 May 2019]


Nanocellulosic materials, such as cellulose nanocrystals, cellulose nanofibers, and bacterial nanocellulose, that display high surface area, mechanical strength, biodegradability, and tunable surface chemistry have attracted great attention over the last decade for biomedical applications. Simultaneously, 3D printing is revolutionizing the field of biomedical engineering, which enables the fast and on-demand printing of customizable scaffolds, tissues, and organs. Nanocellulosic materials hold tremendous potential for 3D bioprinting due to their printability, their shear thinning behavior, their ability to live cell support and owing to their excellent biocompatibility. The amalgamation of nanocellulose-based feedstocks and 3D bioprinting is therefore of critical interest for the development of advanced functional 3D hydrogels. In this context, this review briefly discusses the most recent key developments and challenges in 3D bioprinting nanocellulose-based hydrogel constructs that have been successfully tested for mammalian cell viability and used in tissue engineering applications. View Full-Text
Keywords: nanocellulose; 3D printing; hydrogels; biocompatibility; tissue engineering nanocellulose; 3D printing; hydrogels; biocompatibility; tissue engineering

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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Athukoralalage, S.S.; Balu, R.; Dutta, N.K.; Roy Choudhury, N. 3D Bioprinted Nanocellulose-Based Hydrogels for Tissue Engineering Applications: A Brief Review. Polymers 2019, 11, 898.

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