Next Article in Journal
Large and Giant Unilamellar Vesicle(s) Obtained by Self-Assembly of Poly(dimethylsiloxane)-b-poly(ethylene oxide) Diblock Copolymers, Membrane Properties and Preliminary Investigation of their Ability to Form Hybrid Polymer/Lipid Vesicles
Previous Article in Journal
Preparation of Boron Nitride-Coated Carbon Fibers and Synergistic Improvement of Thermal Conductivity in Their Polypropylene-Matrix Composites
Previous Article in Special Issue
Preparation and Characterization of Superabsorbent Polymers Based on Sawdust
Open AccessArticle

Impact of Crystalline Structural Differences Between α- and β-Chitosan on Their Nanoparticle Formation Via Ionic Gelation and Superoxide Radical Scavenging Activities

1
Department of Fishery Products, Faculty of Fisheries, Kasetsart University, Bangkok 10900, Thailand
2
Division of Biotechnology, School of Bioresources and Technology, King Mongkut′s University of Technology Thonburi, Bangkok 10150, Thailand
3
Center for Advanced Studies for Agriculture and Food (CASAF), Kasetsart University Institute for Advanced Studies, Kasetsart, University, Bangkok 10900, Thailand
*
Author to whom correspondence should be addressed.
Polymers 2019, 11(12), 2010; https://doi.org/10.3390/polym11122010
Received: 21 November 2019 / Revised: 30 November 2019 / Accepted: 2 December 2019 / Published: 4 December 2019
(This article belongs to the Collection Sustainable Polymeric Materials from Renewable Resources)
α- and β-Chitosan nanoparticles were obtained from shrimp shell and squid pen chitosan with different set of deacetylation degree (%DD) and molecular weight (MW) combinations. After nanoparticle formation via ionic gelation with sodium tripolyphosphate (TPP), the % crystallinity index (%CI) of the α- and β-chitosan nanoparticles were reduced to approximately 33% and 43% of the initial %CI of the corresponding α- and βchitosan raw samples, respectively. Both forms of chitosan and chitosan nanoparticles scavenged superoxide radicals in a dose-dependent manner. The %CI of α- and β-chitosan and chitosan nanoparticles was significantly negatively correlated with superoxide radical scavenging abilities over the range of concentration (0.5, 1, 2 and 3 mg/mL) studied. High %DD, and low MW β-chitosan exhibited the highest superoxide radical scavenging activity (p < 0.05). α- and β-Chitosan nanoparticles prepared from high %DD and low MW chitosan demonstrated the highest abilities to scavenge superoxide radicals at 2.0–3.0 mg/mL (p < 0.05), whereas α-chitosan nanoparticles, with the lowest %CI, and smallest particle size (p < 0.05), prepared from medium %DD, and medium MW chitosan showed the highest abilities to scavenge superoxide radicals at 0.5–1.0 mg/mL (p < 0.05). It could be concluded that α- and β-chitosan nanoparticles had superior superoxide radical scavenging abilities than raw chitosan samples.
Keywords: α- and β-chitosan; deacetylation degree; molecular weight; crystalline structure; chitosan nanoparticles; particle size; zeta potential; superoxide radical scavenging activity α- and β-chitosan; deacetylation degree; molecular weight; crystalline structure; chitosan nanoparticles; particle size; zeta potential; superoxide radical scavenging activity
Show Figures

Graphical abstract

MDPI and ACS Style

Jampafuang, Y.; Tongta, A.; Waiprib, Y. Impact of Crystalline Structural Differences Between α- and β-Chitosan on Their Nanoparticle Formation Via Ionic Gelation and Superoxide Radical Scavenging Activities. Polymers 2019, 11, 2010.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop