Green-Based Antimicrobial Hydrogels Prepared from Bagasse Cellulose as 3D-Scaffolds for Wound Dressing
Abstract
:1. Introduction
2. Materials and Methods
2.1. Materials
2.2. Synthesis of Cellulose Grafted with Polyhexamethylene Guanidine Hydrochloride
2.3. Hydrogel Preparation
2.4. Polymer and Hydrogel Characterization
2.5. Compression Test
2.6. Swelling Characterization
2.7. Testing of Antimicrobial Activity
2.8. Cell Viability
3. Results and Discussion
3.1. Hydrogel Characterizations
3.1.1. Antimicrobial Modification of Cellulose with PHGH
3.1.2. Chemical Interactions of Functional Groups in Hydrogel
3.1.3. FTIR of Cellulose and Hydrogel
3.1.4. SEM Analysis
3.2. Swelling Properties
3.3. Mechanical Properties
3.4. Antibacterial Activity of P-SBC and P-CH
3.5. Cytotoxic Characterization of P-CH Dressing
4. Conclusions
Author Contributions
Funding
Conflicts of Interest
References
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Samples | PHGH Contents (wt %) | Growth Inhibition of Cells After 24 h Incubation (%) |
---|---|---|
Control | 0.0 | - |
0.5 | >99.99 | |
P-SBC | 1.0 | >99.99 |
1.5 | >99.99 | |
P-CH | 1.0 | 97.60 |
1.5 | >99.99 |
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Pan, Y.; Zhao, X.; Li, X.; Cai, P. Green-Based Antimicrobial Hydrogels Prepared from Bagasse Cellulose as 3D-Scaffolds for Wound Dressing. Polymers 2019, 11, 1846. https://doi.org/10.3390/polym11111846
Pan Y, Zhao X, Li X, Cai P. Green-Based Antimicrobial Hydrogels Prepared from Bagasse Cellulose as 3D-Scaffolds for Wound Dressing. Polymers. 2019; 11(11):1846. https://doi.org/10.3390/polym11111846
Chicago/Turabian StylePan, Yuanfeng, Xiao Zhao, Xiaoning Li, and Pingxiong Cai. 2019. "Green-Based Antimicrobial Hydrogels Prepared from Bagasse Cellulose as 3D-Scaffolds for Wound Dressing" Polymers 11, no. 11: 1846. https://doi.org/10.3390/polym11111846