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Natural Polymers for Organ 3D Bioprinting

Department of Tissue Engineering, Center of 3D Printing & Organ Manufacturing, School of Fundamental Sciences, China Medical University (CMU), No. 77 Puhe Road, Shenyang North New Area, Shenyang 110122, China
Department of Orthodontics, School of Stomatology, China Medical University, No.117 North Nanjing Street, Shenyang 110003, China
Center of Organ Manufacturing, Department of Mechanical Engineering, Tsinghua University, Beijing 100084, China
Author to whom correspondence should be addressed.
Polymers 2018, 10(11), 1278;
Received: 18 September 2018 / Revised: 17 October 2018 / Accepted: 19 October 2018 / Published: 16 November 2018
(This article belongs to the Special Issue Additive Manufacturing of Polymeric Materials)
PDF [4658 KB, uploaded 16 November 2018]


Three-dimensional (3D) bioprinting, known as a promising technology for bioartificial organ manufacturing, has provided unprecedented versatility to manipulate cells and other biomaterials with precise control their locations in space. Over the last decade, a number of 3D bioprinting technologies have been explored. Natural polymers have played a central role in supporting the cellular and biomolecular activities before, during and after the 3D bioprinting processes. These polymers have been widely used as effective cell-loading hydrogels for homogeneous/heterogeneous tissue/organ formation, hierarchical vascular/neural/lymphatic network construction, as well as multiple biological/biochemial/physiological/biomedical/pathological functionality realization. This review aims to cover recent progress in natural polymers for bioartificial organ 3D bioprinting. It is structured as introducing the important properties of 3D printable natural polymers, successful models of 3D tissue/organ construction and typical technologies for bioartificial organ 3D bioprinting. View Full-Text
Keywords: 3D bioprinting; natural polymers; rapid prototyping (RP); organ manufacturing; implantable bioartificial organs; regenerative medicine 3D bioprinting; natural polymers; rapid prototyping (RP); organ manufacturing; implantable bioartificial organs; regenerative medicine

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Liu, F.; Chen, Q.; Liu, C.; Ao, Q.; Tian, X.; Fan, J.; Tong, H.; Wang, X. Natural Polymers for Organ 3D Bioprinting. Polymers 2018, 10, 1278.

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