Next Article in Journal
Biosynthesis and Characteristics of Aromatic Polyhydroxyalkanoates
Previous Article in Journal
Synergistic Effects of Bitumen Plasticization and Microwave Treatment on Short-Term Devulcanization of Ground Tire Rubber
Article Menu
Issue 11 (November) cover image

Export Article

Open AccessArticle
Polymers 2018, 10(11), 1266;

Enzymatic Degradation of Star Poly(ε-Caprolactone) with Different Central Units

Department of Chemistry, Durham University, Durham DH1 3LE, UK
Austrian Centre of Industrial Biotechnology GmbH, Konrad Lorenz Strasse 20, 3430 Tulln an der Donau, Austria
Institute for Environmental Biotechnology, University of Natural Resources and Life Sciences, Konrad Lorenz Strasse 20, 3430 Tulln an der Donau, Austria
Procter & Gamble, Cobalt 12A, Silver Fox Way, Cobalt Business Park, Newcastle upon Tyne NE27 0QW, UK
Author to whom correspondence should be addressed.
Received: 19 October 2018 / Revised: 9 November 2018 / Accepted: 11 November 2018 / Published: 14 November 2018
(This article belongs to the Special Issue Biocatalytic Functionalization and Degradation of Synthetic Polymers)
Full-Text   |   PDF [2832 KB, uploaded 14 November 2018]   |  


Four-arm star poly(ε-caprolactone) with a central poly(ethylene glycol) PEG unit bridged with 2,2-bis(methyl) propionic acid, (PCL)2-b-PEG-b-(PCL)2, and six-arm star PCL homopolymer with a central dipentaerythritol units were hydrolysed using a lipase from Pseudomonas cepacia and the Thermobifida cellulosilytica cutinase Thc_Cut1. For comparative analysis, Y-shaped copolymers containing methylated PEG bridged with bisMPA, MePEG-(PCL)2, and linear triblock copolymers PCL-b-PEG-b-PCL were also subjected to enzymatic hydrolysis. The hydrophilic nature of the polymers was determined using contact angle analysis, showing that a higher PEG content exhibited a lower contact angle and higher surface wettability. Enzymatic hydrolysis was monitored by % mass loss, scanning electron microscopy (SEM), and differential scanning calorimetry (DSC). A higher rate of mass loss was found for lipase catalysed hydrolysis of those polymers with the highest PEG content, leading to significant surface erosion and increase in crystallinity within the first two days. Liquid chromatography (LC) and size exclusion chromatography (SEC) of samples incubated with the cutinase showed a significant decrease in molecular weight, increase in dispersity, and release of ε-CL monomer units after 6 h of incubation. View Full-Text
Keywords: polycaprolactone; enzyme; biodegradation polycaprolactone; enzyme; biodegradation

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

Share & Cite This Article

MDPI and ACS Style

Blackwell, C.J.; Haernvall, K.; Guebitz, G.M.; Groombridge, M.; Gonzales, D.; Khosravi, E. Enzymatic Degradation of Star Poly(ε-Caprolactone) with Different Central Units. Polymers 2018, 10, 1266.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics



[Return to top]
Polymers EISSN 2073-4360 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top