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Article

Improving Linear Range Limitation of Non-Enzymatic Glucose Sensor by OH Concentration

Department of Materials Science and Engineering, McMaster University, 1280 Main St. W, Hamilton, ON L8S 4L8, Canada
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Crystals 2020, 10(3), 186; https://doi.org/10.3390/cryst10030186
Received: 16 February 2020 / Revised: 3 March 2020 / Accepted: 7 March 2020 / Published: 9 March 2020
(This article belongs to the Special Issue Organic Inorganic Hybrid Perovskite Solar Cells)
The linear range of the non-enzymatic glucose sensor is usually much smaller than the glucose level of diabetic patients, calling for an effective solution. Despite many previous attempts, none have solved the problem. Such a challenge has now been conquered by raising the NaOH concentration in the electrolyte, where amperometry, X-ray diffraction, Fourier-transform infrared spectroscopy, and Nuclear magnetic resonance measurements have been conducted. The linear range has been successfully enhanced to 40 mM in 1000 mM NaOH solution, and it was also found that NaOH affected the degree of glucose oxidation, which influenced the current response during sensing. It was expected that the alkaline concentration must be 25 times higher than the glucose concentration to enhance the linear range, much contrary to prior understanding. View Full-Text
Keywords: non-enzymatic glucose sensor; linear range; mechanism non-enzymatic glucose sensor; linear range; mechanism
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MDPI and ACS Style

Yang, L.W.; Liu, E.E.; Xu, A.F.; Chen, J.Y.; Wang, R.T.; Xu, G. Improving Linear Range Limitation of Non-Enzymatic Glucose Sensor by OH Concentration. Crystals 2020, 10, 186. https://doi.org/10.3390/cryst10030186

AMA Style

Yang LW, Liu EE, Xu AF, Chen JY, Wang RT, Xu G. Improving Linear Range Limitation of Non-Enzymatic Glucose Sensor by OH Concentration. Crystals. 2020; 10(3):186. https://doi.org/10.3390/cryst10030186

Chicago/Turabian Style

Yang, Lory W., Elton E. Liu, Alex F. Xu, Jason Y. Chen, Ryan T. Wang, and Gu Xu. 2020. "Improving Linear Range Limitation of Non-Enzymatic Glucose Sensor by OH Concentration" Crystals 10, no. 3: 186. https://doi.org/10.3390/cryst10030186

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