Total Synthesis and Biological Evaluation of Phaeosphaerides
AbstractThis article reviews studies regarding the total synthesis of phaeosphaerides A and B, nitrogen-containing bicyclic natural products isolated from an endophytic fungus. Numerous synthetic efforts and an X-ray crystal structure analysis of phaeosphaeride A have enabled revision of its originally proposed structure. In addition, a successful protic acid-mediated transformation of phaeosphaeride A to phaeosphaeride B revealed the hypothetical biosynthesis of phaeosphaeride B from phaeosphaeride A. Structure–activity relationship studies of phaeosphaeride derivatives are also discussed. View Full-Text
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Kobayashi, K.; Tanaka, K., III; Kogen, H. Total Synthesis and Biological Evaluation of Phaeosphaerides. Catalysts 2018, 8, 206.
Kobayashi K, Tanaka K, III, Kogen H. Total Synthesis and Biological Evaluation of Phaeosphaerides. Catalysts. 2018; 8(5):206.Chicago/Turabian Style
Kobayashi, Kenichi; Tanaka, Kosaku, III; Kogen, Hiroshi. 2018. "Total Synthesis and Biological Evaluation of Phaeosphaerides." Catalysts 8, no. 5: 206.
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