(1) Background: A disabled student or employee in a certain university faces a large number of obstacles in achieving his/her ordinary duties. An interactive smart search and communication application can support the people at the university campus and Science Park in a number of ways. Primarily, it can strengthen their professional network and establish a responsive eco-system. Therefore, the objective of this research work is to design and implement a unified flexible and adaptable interface. This interface supports an intensive search and communication tool across the university. It would benefit everybody on campus, especially the People with Disabilities (PWDs). (2) Methods: In this project, three main contributions are presented: (A) Assistive Technology (AT) software design and implementation (based on user- and technology-centered design); (B) A wireless sensor network employed to track and determine user’s location; and (C) A novel event behavior algorithm and movement direction algorithm used to monitor and predict users’ behavior and intervene with them and their caregivers when required. (3) Results: This work has developed a comprehensive and universal application with a unified, flexible, and adaptable interface to support the different conditions of PWDs. It has employed an interactive smart based-location service for establishing a smart university Geographic Information System (GIS) solution. This GIS solution has been based on tracking location service, mobility, and wireless sensor network technologies. (4) Conclusion: The proposed system empowered inter-disciplinary interaction between management, staff, researchers, and students, including the PWDs. Identifying the needs of the PWDs has led to the determination of the relevant requirements for designing and implementing a unified flexible and adaptable interface suitable for PWDs on the university campus.
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