In the original publication [1], there was a mistake in Figure 7 as published. Figure 7 contained a duplication of the DAC GFP image (up), taken from the corresponding DAC GFP image published in ref. [1]. As two manuscripts were written with a short time between them, this is the result of an error while copying/pasting the individual pictures used to prepare Figure 7 in this paper. The erroneous picture did not affect the corresponding quantification and the interpretation of the results as this was performed with the correct picture set. The corrected Figure 7 appears below.
Figure 7.
Compounds 2a–c and 4a–c display DNA demethylating activity in human HCT116 colon cancer cells. DAPI (up, blue pictures), fluorescence imaging (up, green pictures) and FACS evaluation (down) of HCT116 cells transfected with methylated pUCHL1 vector and treated for five days with DMSO as a vehicle control (Ctr), with DAC (5 µM) and SGI-1027 (0.5 µM) as reference compounds, and with 2a,b and 4a–c used at 0.5 µM, and 2c used at 0.1 µM.
The authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated.
Reference
- Zwergel, C.; Fioravanti, R.; Stazi, G.; Sarno, F.; Battistelli, C.; Romanelli, A.; Nebbioso, A.; Mendes, E.; Paulo, A.; Strippoli, R.; et al. Novel Quinoline Compounds Active in Cancer Cells through Coupled DNA Methyltransferase Inhibition and Degradation. Cancers 2020, 12, 447. [Google Scholar] [CrossRef] [PubMed]
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