Safety and Diagnostic Efficacy of Image-Guided Biopsy of Small Renal Masses
Abstract
:Simple Summary
Abstract
1. Introduction
2. Materials and Methods
2.1. Study Population
2.2. Biopsies
2.3. Post-Biopsy Renal Mass Management
2.4. Analysis
3. Results
3.1. Study Population and Mass Characteristics
3.2. Biopsies
3.3. Safety
3.4. Technical Success
3.5. Post-Biopsy Renal Mass Management
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Features | Number (%) |
---|---|
Number of patients included | 167 |
Median age (range) (years) | 65 (26–86) |
Gender | |
Male | 86 (51%) |
Female | 81 (49%) |
Median size (range) (cm) | 2.6 (1–4) |
Mass side | |
Left kidney | 95 (57%) |
Right kidney | 72 (43%) |
Mass location | |
Lower pole | 63 (38%) |
Interpolar | 55 (33%) |
Upper pole | 49 (29%) |
Patient position | |
Prone | 145 (87%) |
Supine | 22 (13%) |
Imaging technique used | |
US | 101 (60%) |
CT | 55 (33%) |
US/CT | 10 (6%) |
MRI | 1 (1%) |
Needle type | |
Temno | 102 (61%) |
BioPince | 31 (18%) |
Temno/BioPince | 11 (7%) |
Not documented | 23 (14%) |
Median number of specimens (range) | 4 (1–9) |
Complications | Number (%) |
---|---|
Perinephric hematoma (Grade A) | 6 (3%) |
Retroperitoneal hematoma (Grade A) | 1 (1%) |
Pain (Grade B) | 1 (1%) |
Pyelonephritis (Grade D) | 1 (1%) |
Features | Number (%) |
---|---|
Number of patients | 9 |
Median size (range) (cm) | 4 (1.6–4) |
Mass side | |
Left kidney | 5 (55%) |
Right kidney | 4 (45%) |
Mass location | |
Lower pole | 4 (44%) |
Interpolar | 3 (33%) |
Upper pole | 2 (23%) |
Patient position | |
Prone | 7 (78%) |
Supine | 2 (22%) |
Imaging technique used | |
US | 4 (44%) |
CT | 3 (33%) |
US/CT | 2 (23%) |
Needle type | |
Temno | 3 (33%) |
BioPince | 2 (23%) |
Temno/BioPince | 3 (33%) |
Not documented | 1 (11%) |
Median number of specimens (range) | 2.5 (1–5) |
Anticoagulation use | |
Heparin | 1 (11%) |
Apixaban | 1 (11%) |
None | 7 (78%) |
Stratification Criteria | Success | Chi-Square Test p-Value |
---|---|---|
Mass side (left/right) | 84 (88%)/67 (93%) | 0.3 |
Mass location (upper/interpolar/lower) | 47 (96%)/48 (87%)/56 (89%) | 0.2 |
Patient position (prone/supine) | 133 (95%)/18 (90%) | 0.2 |
Imaging modality (US/CT/US/CT) | 92 (93%)/49 (89%)/9 (82%) | 0.5 |
Needle size (18 G/20 G/18/20 G) | 76 (88%)/53 (95%)/14 (93%) | 0.5 |
Pathologic Diagnosis | Number (%) |
---|---|
RCC | 95 (65%) |
Clear cell (Low Fuhrman’s nuclear grade 74% (32/43 available grades); High Fuhrman’s nuclear grade 26% (11/43 available grades) | 52 (55%) |
Papillary (Low Fuhrman’s nuclear grade 65% (15/23 available grades; High Fuhrman’s nuclear grade 35% 8/23 available grade) | 35 (37%) |
Chromophobe | 8 (8%) |
Oncocytoma | 27 (18%) |
Clear cell papillary renal cell tumor | 14 (9%) |
Angiomyolipoma | 6 (4%) |
Xanthogranulomatous pyelonephritis | 1 (1%) |
Lymphoma | 2 (1%) |
High-grade papillary urothelial carcinoma | 1 (1%) |
Metanephric adenoma | 1 (1%) |
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Serhal, M.; Rangwani, S.; Seedial, S.M.; Thornburg, B.; Riaz, A.; Nemcek, A.A., Jr.; Sato, K.T.; Perry, K.T., Jr.; Choy, B.; Lewandowski, R.J.; et al. Safety and Diagnostic Efficacy of Image-Guided Biopsy of Small Renal Masses. Cancers 2024, 16, 835. https://doi.org/10.3390/cancers16040835
Serhal M, Rangwani S, Seedial SM, Thornburg B, Riaz A, Nemcek AA Jr., Sato KT, Perry KT Jr., Choy B, Lewandowski RJ, et al. Safety and Diagnostic Efficacy of Image-Guided Biopsy of Small Renal Masses. Cancers. 2024; 16(4):835. https://doi.org/10.3390/cancers16040835
Chicago/Turabian StyleSerhal, Muhamad, Sean Rangwani, Stephen M. Seedial, Bartley Thornburg, Ahsun Riaz, Albert A. Nemcek, Jr., Kent T. Sato, Kent T. Perry, Jr., Bonnie Choy, Robert J. Lewandowski, and et al. 2024. "Safety and Diagnostic Efficacy of Image-Guided Biopsy of Small Renal Masses" Cancers 16, no. 4: 835. https://doi.org/10.3390/cancers16040835
APA StyleSerhal, M., Rangwani, S., Seedial, S. M., Thornburg, B., Riaz, A., Nemcek, A. A., Jr., Sato, K. T., Perry, K. T., Jr., Choy, B., Lewandowski, R. J., & Gordon, A. C. (2024). Safety and Diagnostic Efficacy of Image-Guided Biopsy of Small Renal Masses. Cancers, 16(4), 835. https://doi.org/10.3390/cancers16040835