Center of Ophthalmology, University of Tuebingen, 72076 Tuebingen, Germany
Singapore National Eye Centre, 11 Third Hospital Avenue, Singapore 168751, Singapore
Singapore Eye Research Institute, 11 Third Hospital Avenue, Singapore 168751, Singapore
Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 168751, Singapore
Duke-NUS Medical School, Singapore 168751, Singapore
Department of Ophthalmology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
College of Medicine & Public Health, Flinders University, Adelaide 5042, Australia
Institute for Pathology and Neuropathology, University of Tuebingen, 72076 Tuebingen, Germany
Miyata Eye Hospital, Miyakonojo, Miyazaki 885-0051, Japan
Author to whom correspondence should be addressed.
Academic Editors: Nathalie Cassoux and Ryuya Yamanaka
Received: 10 June 2021
Revised: 16 July 2021
Accepted: 20 July 2021
Published: 4 August 2021
Vitreoretinal lymphoma is a variant of primary CNS lymphoma involving the retina and/or the vitreous. At the time of presentation, CNS involvement occurs in up to one-third of patients. However, 50–90% of patients develop a CNS and/or spinal cord disease within one year. Therefore, it is important to frequently examine and recognize the early symptoms of CNS involvement. This review summarizes the clinical signs, ocular diagnosis and treatment of vitreoretinal lymphoma.