Next Article in Journal
Detecting Progression of Melanocytic Choroidal Tumors by Sequential Imaging: Is Ultrasonography Necessary?
Previous Article in Journal
Glutamic-Pyruvic Transaminase 1 Facilitates Alternative Fuels for Hepatocellular Carcinoma Growth—A Small Molecule Inhibitor, Berberine
 
 
Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
Journals
Cancers
Volume 12
Issue 7
10.3390/cancers12071855
cancers-logo
Submit to this Journal Review for this Journal Propose a Special Issue
► Article Menu

Article Menu

share Share announcement Help format_quote Cite question_answer Discuss in SciProfiles
first_page
settings
Order Article Reprints
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
Article

Precision Science on Incidence and Progression of Early-Detected Small Breast Invasive Cancers by Mammographic Features

by
Rene Wei-Jung Chang
1,
Shu-Lin Chuang
2,
Chen-Yang Hsu
1,
Amy Ming-Fang Yen
3,
Wendy Yi-Ying Wu
4,
Sam Li-Sheng Chen
3,
Jean Ching-Yuan Fann
5,
Laszlo Tabar
6,
Robert A. Smith
7,
Stephen W. Duffy
8,
Sherry Yueh-Hsia Chiu
9,10,* and
Hsiu-Hsi Chen
1,*
1
Institute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei City 100, Taiwan
2
Department of Medical Research, National Taiwan University Hospital, Taipei City 100, Taiwan
3
School of Oral Hygiene, College of Oral Medicine, Taipei Medical University, Taipei City 110, Taiwan
4
Department of Radiation Sciences, Oncology, Umeå University, 90187 Umeå, Sweden
5
Department of Health Industry Management, College of Healthcare Management, Kainan University, Taoyuan City 338, Taiwan
6
Department of Mammography, Falun Central Hospital, 791823 Falun, Sweden
7
Center for Cancer Screening, American Cancer Society, Atlanta, GA 30303, USA
8
Centre for Cancer Prevention, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, UK
9
Department of Health Care Management, College of Management, Chang Gung University, Taoyuan City 333, Taiwan
10
Division of Hepatogastroenterology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung City 833, Taiwan
*
Authors to whom correspondence should be addressed.
Cancers 2020, 12(7), 1855; https://doi.org/10.3390/cancers12071855
Submission received: 22 May 2020 / Revised: 25 June 2020 / Accepted: 6 July 2020 / Published: 10 July 2020
(This article belongs to the Section Cancer Causes, Screening and Diagnosis)
Browse Figures
Review Reports Versions Notes

Abstract

The aim was to evaluate how the inter-screening interval affected the performance of screening by mammographic appearances. This was a Swedish retrospective screening cohort study with information on screening history and mammography features in two periods (1977–1985 and 1996–2010). The pre-clinical incidence and the mean sojourn time (MST) for small breast cancer allowing for sensitivity by mammographic appearances were estimated. The percentage of interval cancer against background incidence (I/E ratio) was used to assess the performance of mammography screening by different inter-screening intervals. The sensitivity-adjusted MSTs (in years) were heterogeneous with mammographic features, being longer for powdery and crushed stone-like calcifications (4.26, (95% CI, 3.50–5.26)) and stellate masses (3.76, (95% CI, 3.15–4.53)) but shorter for circular masses (2.65, (95% CI, 2.06–3.55)) in 1996–2010. The similar trends, albeit longer MSTs, were also noted in 1977–1985. The I/E ratios for the stellate type were 23% and 32% for biennial and triennial screening, respectively. The corresponding figures were 32% and 43% for the circular type and 21% and 29% for powdery and crushed stone-like calcifications, respectively. Mammography-featured progressions of small invasive breast cancer provides a new insight into personalized quality assurance, surveillance, treatment and therapy of early-detected breast cancer.
Keywords: breast cancer; interval cancer; mammography; sensitivity; sojourn time breast cancer; interval cancer; mammography; sensitivity; sojourn time

Share and Cite

MDPI and ACS Style

Chang, R.W.-J.; Chuang, S.-L.; Hsu, C.-Y.; Yen, A.M.-F.; Wu, W.Y.-Y.; Chen, S.L.-S.; Fann, J.C.-Y.; Tabar, L.; Smith, R.A.; Duffy, S.W.; et al. Precision Science on Incidence and Progression of Early-Detected Small Breast Invasive Cancers by Mammographic Features. Cancers 2020, 12, 1855. https://doi.org/10.3390/cancers12071855

AMA Style

Chang RW-J, Chuang S-L, Hsu C-Y, Yen AM-F, Wu WY-Y, Chen SL-S, Fann JC-Y, Tabar L, Smith RA, Duffy SW, et al. Precision Science on Incidence and Progression of Early-Detected Small Breast Invasive Cancers by Mammographic Features. Cancers. 2020; 12(7):1855. https://doi.org/10.3390/cancers12071855

Chicago/Turabian Style

Chang, Rene Wei-Jung, Shu-Lin Chuang, Chen-Yang Hsu, Amy Ming-Fang Yen, Wendy Yi-Ying Wu, Sam Li-Sheng Chen, Jean Ching-Yuan Fann, Laszlo Tabar, Robert A. Smith, Stephen W. Duffy, and et al. 2020. "Precision Science on Incidence and Progression of Early-Detected Small Breast Invasive Cancers by Mammographic Features" Cancers 12, no. 7: 1855. https://doi.org/10.3390/cancers12071855

APA Style

Chang, R. W.-J., Chuang, S.-L., Hsu, C.-Y., Yen, A. M.-F., Wu, W. Y.-Y., Chen, S. L.-S., Fann, J. C.-Y., Tabar, L., Smith, R. A., Duffy, S. W., Chiu, S. Y.-H., & Chen, H.-H. (2020). Precision Science on Incidence and Progression of Early-Detected Small Breast Invasive Cancers by Mammographic Features. Cancers, 12(7), 1855. https://doi.org/10.3390/cancers12071855

Note that from the first issue of 2016, this journal uses article numbers instead of page numbers. See further details here.

Article Metrics

Back to TopTop