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Review

Can Bioelectrical Impedance Analysis and BMI Be a Prognostic Tool in Head and Neck Cancer Patients? A Review of the Evidence

1
Department of Food Science and Nutrition, School of Environment, University of the Aegean, Myrina, 814 00 Lemnos, Greece
2
Radiation Oncology Department, University of Thessaly, School of Health Sciences, Faculty of Medicine, 413 34 Larissa, Greece
3
Department of Surgery, Medical School, University of Thessaly, 413 34 Larissa, Greece
4
Department of Nutritional Sciences and Dietetics, Hellenic International University, 570 01 Thessaloniki, Greece
5
Department of Health Sciences, CNHS, Zayed University, Abu Dhabi 144534, UAE
*
Author to whom correspondence should be addressed.
Cancers 2020, 12(3), 557; https://doi.org/10.3390/cancers12030557
Received: 13 January 2020 / Revised: 23 February 2020 / Accepted: 25 February 2020 / Published: 28 February 2020
(This article belongs to the Special Issue Head and Neck Cancers)
Background: Malnutrition can significantly affect disease progression and patient survival. The efficiency of weight loss and bioimpedance analysis (BIA)-derived measures in the evaluation of malnutrition, and disease progression and prognosis in patients with head and neck cancer (HNC) are an important area of research. Method: The PubMed database was thoroughly searched, using relative keywords in order to identify clinical trials that investigated the role of BIA-derived measures and weight loss on the disease progression and prognosis of patients with HNC. Twenty-seven studies met the criteria. More specifically, six studies examined the prognostic role of the tissue electrical properties in HNC patients; five examined the role of the tissue electrical properties on identifying malnutrition; four studies looked at the changes in the tissue electrical properties of HNC patients; and 12 examined the prognostic role of weight loss on survival and/or treatment outcomes. Results: Several studies have investigated the role of nutritional status tools on prognosis in HNC patients. Current studies investigating the potential of BIA-derived raw data have shown that phase angle (PA) and capacitance of the cell membrane may be considered prognostic factors of survival. Weight loss may be a prognostic factor for treatment toxicity and survival, despite some conflicting evidence. Conclusions: Further studies are recommended to clarify the role of BIA-derived measures on patients’ nutritional status and the impact of PA on clinical outcomes as well as the prognostic role of weight loss. View Full-Text
Keywords: head and neck cancer; bioelectrical impedance analysis; body mass index; weight loss; prognostic factor head and neck cancer; bioelectrical impedance analysis; body mass index; weight loss; prognostic factor
MDPI and ACS Style

Mantzorou, M.; Tolia, M.; Poultsidi, A.; Pavlidou, E.; Papadopoulou, S.K.; Papandreou, D.; Giaginis, C. Can Bioelectrical Impedance Analysis and BMI Be a Prognostic Tool in Head and Neck Cancer Patients? A Review of the Evidence. Cancers 2020, 12, 557. https://doi.org/10.3390/cancers12030557

AMA Style

Mantzorou M, Tolia M, Poultsidi A, Pavlidou E, Papadopoulou SK, Papandreou D, Giaginis C. Can Bioelectrical Impedance Analysis and BMI Be a Prognostic Tool in Head and Neck Cancer Patients? A Review of the Evidence. Cancers. 2020; 12(3):557. https://doi.org/10.3390/cancers12030557

Chicago/Turabian Style

Mantzorou, Maria, Maria Tolia, Antigoni Poultsidi, Eleni Pavlidou, Sousana K. Papadopoulou, Dimitrios Papandreou, and Constantinos Giaginis. 2020. "Can Bioelectrical Impedance Analysis and BMI Be a Prognostic Tool in Head and Neck Cancer Patients? A Review of the Evidence" Cancers 12, no. 3: 557. https://doi.org/10.3390/cancers12030557

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