Can Bioelectrical Impedance Analysis and BMI Be a Prognostic Tool in Head and Neck Cancer Patients? A Review of the Evidence

Mantzorou, Maria; Tolia, Maria; Poultsidi, Antigoni; Pavlidou, Eleni; Papadopoulou, Sousana K.; Papandreou, Dimitrios; Giaginis, Constantinos

doi:10.3390/cancers12030557

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Can Bioelectrical Impedance Analysis and BMI Be a Prognostic Tool in Head and Neck Cancer Patients? A Review of the Evidence

²,

³,

Sousana K. Papadopoulou

⁴

Dimitrios Papandreou

^5,*

and

Constantinos Giaginis

Department of Food Science and Nutrition, School of Environment, University of the Aegean, Myrina, 814 00 Lemnos, Greece

Radiation Oncology Department, University of Thessaly, School of Health Sciences, Faculty of Medicine, 413 34 Larissa, Greece

Department of Surgery, Medical School, University of Thessaly, 413 34 Larissa, Greece

⁴

Department of Nutritional Sciences and Dietetics, Hellenic International University, 570 01 Thessaloniki, Greece

⁵

Department of Health Sciences, CNHS, Zayed University, Abu Dhabi 144534, UAE

Author to whom correspondence should be addressed.

Cancers 2020, 12(3), 557; https://doi.org/10.3390/cancers12030557

Received: 13 January 2020 / Revised: 23 February 2020 / Accepted: 25 February 2020 / Published: 28 February 2020

(This article belongs to the Special Issue Head and Neck Cancers)

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Abstract

Background: Malnutrition can significantly affect disease progression and patient survival. The efficiency of weight loss and bioimpedance analysis (BIA)-derived measures in the evaluation of malnutrition, and disease progression and prognosis in patients with head and neck cancer (HNC) are an important area of research. Method: The PubMed database was thoroughly searched, using relative keywords in order to identify clinical trials that investigated the role of BIA-derived measures and weight loss on the disease progression and prognosis of patients with HNC. Twenty-seven studies met the criteria. More specifically, six studies examined the prognostic role of the tissue electrical properties in HNC patients; five examined the role of the tissue electrical properties on identifying malnutrition; four studies looked at the changes in the tissue electrical properties of HNC patients; and 12 examined the prognostic role of weight loss on survival and/or treatment outcomes. Results: Several studies have investigated the role of nutritional status tools on prognosis in HNC patients. Current studies investigating the potential of BIA-derived raw data have shown that phase angle (PA) and capacitance of the cell membrane may be considered prognostic factors of survival. Weight loss may be a prognostic factor for treatment toxicity and survival, despite some conflicting evidence. Conclusions: Further studies are recommended to clarify the role of BIA-derived measures on patients’ nutritional status and the impact of PA on clinical outcomes as well as the prognostic role of weight loss. View Full-Text

Keywords: head and neck cancer; bioelectrical impedance analysis; body mass index; weight loss; prognostic factor

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MDPI and ACS Style

Mantzorou, M.; Tolia, M.; Poultsidi, A.; Pavlidou, E.; Papadopoulou, S.K.; Papandreou, D.; Giaginis, C. Can Bioelectrical Impedance Analysis and BMI Be a Prognostic Tool in Head and Neck Cancer Patients? A Review of the Evidence. Cancers 2020, 12, 557. https://doi.org/10.3390/cancers12030557

AMA Style

Mantzorou M, Tolia M, Poultsidi A, Pavlidou E, Papadopoulou SK, Papandreou D, Giaginis C. Can Bioelectrical Impedance Analysis and BMI Be a Prognostic Tool in Head and Neck Cancer Patients? A Review of the Evidence. Cancers. 2020; 12(3):557. https://doi.org/10.3390/cancers12030557

Chicago/Turabian Style

Mantzorou, Maria, Maria Tolia, Antigoni Poultsidi, Eleni Pavlidou, Sousana K. Papadopoulou, Dimitrios Papandreou, and Constantinos Giaginis. 2020. "Can Bioelectrical Impedance Analysis and BMI Be a Prognostic Tool in Head and Neck Cancer Patients? A Review of the Evidence" Cancers 12, no. 3: 557. https://doi.org/10.3390/cancers12030557

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Can Bioelectrical Impedance Analysis and BMI Be a Prognostic Tool in Head and Neck Cancer Patients? A Review of the Evidence

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