Associations of Epstein-Barr Virus-Positive Gastric Adenocarcinoma with Circulating Mediators of Inflammation and Immune Response
Abstract
1. Introduction
2. Results
3. Discussion
4. Patients and Methods
5. Conclusions
Author Contributions
Funding
Conflicts of Interest
References
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Protein (Other Names) | Marker Level Tertile | Age- and Sex-Adjusted OR (95% CI) |
---|---|---|
CCL20 (MIP-3A) | 1 | 1.0 |
2 | 2.33 (0.57–9.49) | |
3 | 12.30 (2.68–56.36) | |
p-trend | 0.001 | |
AUC | 0.76 | |
CXCL9 (MIG, EBV-induced molecule 1 ligand chemokine) | 1 | 1.0 |
2 | 2.17 (0.44–10.81) | |
3 | 11.49 (2.08–63.55) | |
p-trend | 0.003 | |
AUC | 0.74 | |
PD-L1 (CD274) | 1 | 1.0 |
2 | 5.80 (0.96–35.18) | |
3 | 13.73 (2.21–85.07) | |
p-trend | 0.004 | |
AUC | 0.73 | |
IL-10 | 1 | 1.0 |
2 | 2.91 (0.73–11.61) | |
3 | 5.72 (1.33–24.65) | |
p-trend | 0.019 | |
AUC | 0.67 | |
CCL19 (MIP-3B) | 1 | 1.0 |
2 | 1.12 (0.30–4.20) | |
3 | 5.03 (1.30–19.49) | |
p-trend | 0.019 | |
AUC | 0.67 | |
CCL11 (Eotaxin-1) | 1 | 1.0 |
2 | 1.57 (0.41–6.09) | |
3 | 4.74 (1.18–19.02) | |
p-trend | 0.026 | |
AUC | 0.70 | |
IL-17A | 1 | 1.0 |
2 | 4.29 (1.11–16.64) | |
3 | 4.28 (1.09–16.80) | |
p-trend | 0.038 | |
AUC | 0.67 | |
CCL8 (MCP-2) | 1 | 1.0 |
2 | 2.10 (0.56–7.88) | |
3 | 3.72 (1.01–13.75) | |
p-trend | 0.049 | |
AUC | 0.67 |
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Camargo, M.C.; Sivins, A.; Isajevs, S.; Folkmanis, V.; Rudzīte, D.; Gulley, M.L.; Offerhaus, G.J.; Leja, M.; Rabkin, C.S. Associations of Epstein-Barr Virus-Positive Gastric Adenocarcinoma with Circulating Mediators of Inflammation and Immune Response. Cancers 2018, 10, 284. https://doi.org/10.3390/cancers10090284
Camargo MC, Sivins A, Isajevs S, Folkmanis V, Rudzīte D, Gulley ML, Offerhaus GJ, Leja M, Rabkin CS. Associations of Epstein-Barr Virus-Positive Gastric Adenocarcinoma with Circulating Mediators of Inflammation and Immune Response. Cancers. 2018; 10(9):284. https://doi.org/10.3390/cancers10090284
Chicago/Turabian StyleCamargo, M. Constanza, Armands Sivins, Sergejs Isajevs, Valdis Folkmanis, Dace Rudzīte, Margaret L. Gulley, G. Johan Offerhaus, Marcis Leja, and Charles S. Rabkin. 2018. "Associations of Epstein-Barr Virus-Positive Gastric Adenocarcinoma with Circulating Mediators of Inflammation and Immune Response" Cancers 10, no. 9: 284. https://doi.org/10.3390/cancers10090284
APA StyleCamargo, M. C., Sivins, A., Isajevs, S., Folkmanis, V., Rudzīte, D., Gulley, M. L., Offerhaus, G. J., Leja, M., & Rabkin, C. S. (2018). Associations of Epstein-Barr Virus-Positive Gastric Adenocarcinoma with Circulating Mediators of Inflammation and Immune Response. Cancers, 10(9), 284. https://doi.org/10.3390/cancers10090284