AbstractThe tumor suppressor p53 as the “guardian of the genome” plays an essential role in numerous signaling pathways that control the cell cycle, cell death and in maintaining the integrity of the human genome. p53, depending on the intracellular localization, contributes to the regulation of various cell death pathways, including apoptosis, autophagy and necroptosis. Accumulated evidence suggests that this function of p53 is closely involved in the process of cancer development. Here, present knowledge concerning a p53-autophagy-metastasis link, as well as therapeutic approaches that influence this link, are discussed. View Full-Text
Share & Cite This Article
Denisenko, T.V.; Pivnyuk, A.D.; Zhivotovsky, B. p53-Autophagy-Metastasis Link. Cancers 2018, 10, 148.
Denisenko TV, Pivnyuk AD, Zhivotovsky B. p53-Autophagy-Metastasis Link. Cancers. 2018; 10(5):148.Chicago/Turabian Style
Denisenko, Tatiana V.; Pivnyuk, Anastasia D.; Zhivotovsky, Boris. 2018. "p53-Autophagy-Metastasis Link." Cancers 10, no. 5: 148.
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.